关键词: 卒中, 缺血性卒中, 生活质量, 康复, 危险因素

Abstract: Background　Patients are showing increasing care about quality of life as healthcare advances. Improving quality of life is a means for addressing the contradiction between increasing needs for a better life and imbalanced or inadequate socioeconomic development. Objective　To investigate the status of quality of life and associated factors in patients with ischemic stroke at different periods，providing a basis for improving quality of life of this population. Methods　One hundred and twenty patients with ischemic stroke were recruited from Department of Rehabilitation Medicine and Department of Neurology，First Affiliated Hospital，School of Medicine，Shihezi University from June 2017 to September 2019. Risk factors of stroke，quality of life assessed using the Stroke-specific Quality of Life Scale （SS-QOL） within three to five days of admission，one and three months after onset were collected. Univariate analysis and multiple linear regression analysis were used to investigate the factors influencing quality of life at the above-mentioned three periods. Results　Multiple linear regression analysis revealed that older age，having no health insurance，higher body mass index （BMI），smoking/drinking history，diabetes，hyperlipidemia，higher Modified Rankin Scale score and conservative treatment were independent risk factors of poor quality of life within three to five days of admission （P<0.05）；older age，having no health insurance，higher BMI，smoking/drinking history，hypertension，diabetes，and hyperhomocysteinemia were independent risk factors for poor quality of life at one month after admission （P<0.05）；older age，lower education level，having no health insurance，higher BMI，smoking/drinking history，hypertension，diabetes，hyperhomocysteinemia and conservative treatment were independent risk factors of poor quality of life at three months after admission （P<0.05）. Conclusion　The factors affecting the quality of life of stroke survivors in different periods are different. Only by paying attention to different influencing factors in different periods can stroke patients be better managed in the whole course of disease.

Key words: Stroke, Ischemic stroke, Quality of life, Rehabilitation, Risk factors