关键词: 静脉, 药物疗法管理, 给药系统, 医院, 信息化, 静脉安全用药管理模式, 近似错误, 全程追溯

Abstract: Background　Intravenous medication has become an important administration means because of its clear and rapid effect.A small mistake in the process of intravenous administration may lead to serious consequences.So ensuring the safety of medication is the basis of today's medical safety.Objective　To develop a management model for intravenous medication safety using information technology，safeguarding the medication safety of patients.Methods　This study was carried out in Shaoxing People's Hospital during March to September 2019.Participants were randomly recruited from 3 clinical departments（No.2 Hepatobiliopancreatology，Hematology and Cardiothoracic Surgery ）using the original intravenous medication management model during March to May（control group，consisting of 41 537 subgroups），and from other clinical departments（No.1 Hepatobiliopancreatology，No.1 Respiratory Medicine and GI Medicine）using the new management model for intravenous medication safety（developed using the information technology，namely，adding a warning module in the computerized physician order entry system，limiting or reminding the amount of glucose to be used in diabetic patients or allergic drugs to be used in patients，and adding a scanning segment at the end of infusion，realizing the traceability of the whole process of infusion）during July to September（observation group，consisting of 39 132 subgroups）.The overall incidence of the possibilities of making intravenous medication errors（approximate errors in glucose use and drug allergy intervention）and the completion rates of intravenous infusion process based on traceability were compared between the two groups.Results　The overall incidence of approximate errors in glucose use and drug allergy intervention in the observation group was lower than that in the control group（0.02% vs 0.56%，0.03% vs 0.32%，respectively，P<0.05）.The completion rates of intravenous infusion process based on traceability in the control group and observation group were 0 and 97.34%，respectively.Conclusion　Our management model for intravenous medication safety developed based on informatization may reduce the potential unsafe risk factors of intravenous medication，and the possibilities of making intravenous medication errors.Moreover，the traceability of whole process of intravenous infusion may be realized，by which individual responsibility for errors may be distinguished.Furthermore，the application of the model is conducive to enhancing scientific and rational drug use，ensuring the safety of patients，and improving the medical quality continuously.

Key words: Veins；Medication therapy management；Medication systems, hospital；Informatization；Management model for intravenous medication safety；Approximate error；Whole course tracing