Chronic non-specific low back pain (CNLBP) is a highly prevalent musculoskeletal disease worldwide, which severely impairs patients' quality of life. Most existing studies primarily focus on biomechanical improvements while neglecting the modulatory role of the central nervous system in pain perception. From three perspectives-neurophysiology, biomechanics, and integrated traditional Chinese and Western medicine-this study aims to explore novel strategies for the prevention and treatment of CNLBP.

To compare the clinical efficacy of manual therapy (tendon-regulating and bone-setting ) combined with dynamic neuromuscular stabilization (DNS) for patients with chronic non-specific low back pain.

A total of 72 chronic non-specific low back pain (CNLBP) patients admitted to the Tendon Injury Outpatient Department of the First Clinical Medical College, Anhui University of Chinese Medicine from August 2024 to August 2025 were randomly divided into two groups (1∶1) via a computer-generated random number table, with 36 cases each. Three patients withdrew due to personal reasons (1 in the experimental group, 2 in the control group). The control group received sham manipulation plus DNS training (3 times/week for 4 weeks), while the experimental group received tendon-regulating and bone-setting manipulation plus DNS training (2 times/week for 4 weeks). Visual Analogue Scale (VAS), Roland-Morris Disability Questionnaire (RMQ), Pain Catastrophizing Scale (PCS) scores, and surface electromyography (sEMG) co-contraction ratio (CCR) of lumbar and abdominal muscles were compared before and after treatment, with adverse events monitored.

Before treatment, there were no significant differences in the baseline data between the two groups (P>0.05). After treatment, the VAS score, RMQ score, PCS and its subscale scores, as well as the surface electromyography CCR of the lumbocrural and abdominal muscles in both groups were significantly improved compared with those before treatment (P<0.05); moreover, the degree of improvement in the experimental group was significantly superior to that in the control group (P<0.05).

Tendon-regulating and bone-setting manipulation combined with DNS can effectively alleviate pain, improve functional impairment and pain catastrophizing thinking, enhance muscle co-contraction function, and show good safety. Its clinical efficacy is superior to that of DNS monotherapy.

慢性非特异性腰痛（CNLBP）是全球高发的肌肉骨骼系统疾病，严重影响患者的生活质量。现有研究多聚焦生物力学改善，而忽视了中枢神经的疼痛调控作用。本研究从神经生理、生物力学、中西医结合三维视角切入，探索CNLBP的防治新思路。

比较理筋正骨手法联合动态神经肌肉稳定技术（DNS）治疗CNLBP的临床疗效。

选取2024年8月—2025年8月来自安徽中医药大学第一临床医学院筋伤门诊收治的CNLBP患者72例，按照计算机随机数字表法进行1∶1分组，分为试验组（n=36）和对照组（n=36），其中3例因个人原因放弃参与研究（试验组1例，对照组2例）。对照组接受假手法+DNS训练，3次/周，共治疗4周，试验组接受理筋正骨手法治疗+DNS训练，2次/周，共治疗4周。比较两组患者治疗前后疼痛视觉模拟量表（VAS）评分、Roland-Morris功能障碍问卷（RMQ）评分、疼痛灾难化量表（PCS）评分及腰腹部肌肉表面肌电（sEMG）协同收缩率（CCR），并监测不良事件。

治疗前，两组患者基线资料比较差异无统计学意义（P>0.05）；治疗后两组患者VAS评分、RMQ评分、PCS及各分量表评分和sEMG的CCR均较治疗前显著改善（P<0.05），且试验组改善程度均显著优于对照组（P<0.05）。

理筋正骨手法联合DNS治疗CNLBP可有效缓解疼痛，改善功能障碍及疼痛灾难化思维，并提升肌肉协同收缩功能，且安全性良好，疗效优于单纯DNS治疗。