Chinese General Practice ›› 2025, Vol. 28 ›› Issue (18): 2247-2252.DOI: 10.12114/j.issn.1007-9572.2024.0119

• Article • Previous Articles     Next Articles

Carotid Artery Calcification Features in Plaque Stability and Clinical Events

  

  1. Department of Radiology, Lianyungang Clinical Medical College of Nanjing Medical University, Lianyungang 222004, China
  • Received:2024-04-03 Revised:2024-06-25 Published:2025-06-20 Online:2025-04-25
  • Contact: GU Yan

颈动脉钙化特征在评估斑块稳定性及临床事件中的作用

  

  1. 222004 江苏省连云港市,南京医科大学连云港临床医学院放射科
  • 通讯作者: 顾艳
  • 作者简介:

    作者贡献:

    褚田雨负责构思与设计、研究资料的收集与整理、论文撰写;顾艳负责论文修订、文章的质量控制及审校,对文章整体负责,监督管理。

Abstract:

Carotid atherosclerosis is a degenerative disease that is a hemodynamic change caused by endothelial dysfunction and is an important cause of stroke, and the assessment of plaque stability plays an important role in predicting future clinical events. However, there is controversy in studies on the impact of calcification features on plaque stability. Previous studies have mostly categorized calcifications by their size, number, location, or shape, and explored their role in assessing plaque stability and clinical events. Based on a review of the previous literature, this article explores the correlation between calcification research and plaque stability and its value in predicting clinical events, and puts forward the existing problems and thoughts on future research directions, aiming to provide reference for research in this field.

Key words: Stroke, Atherosclerosis, Vascular calcification, Review

摘要:

颈动脉粥样硬化是一种退行性疾病,是由内皮功能障碍引起的血流动力学改变,是引发脑卒中的重要原因,斑块稳定性的评估在预测未来临床事件中发挥重要作用。然而,在关于钙化特征对斑块稳定性影响的研究中仍存在争议。既往研究大多通过钙化的大小、数量、位置或形状等特征进行分类,并探讨其在评估斑块稳定性及临床事件中的作用。本文通过对既往文献的回顾,从钙化研究的不同分类方法入手,探究其与斑块稳定性的相关性,以及对临床事件的预测价值,同时提出了存在的问题及对未来研究方向的思考,旨在为该领域的研究提供参考。

关键词: 卒中, 动脉粥样硬化, 血管钙化, 综述