Recent Advances in Clinical Management of Takayasu's Arteritis in Pregnancy

doi:10.12114/j.issn.1007-9572.2022.0665

Abstract

Abstract:

Takayasu's arteritis (TA) is a chronic granulomatous vasculitis mainly affecting the aorta and its major branches, which can cause stenosis, occlusion and aneurysm formation, severely influencing the affected women of childbearing age. TA has been extensively studied to be stable during pregnancy, but it may lead to pregnancy complications such as gestational hypertension, pre-eclampsia, preterm delivery, and intrauterine growth restriction. To reduce the adverse effects of TA on the mother and fetus, it is essential to control the disease activity during pregnancy. This article details the effects of TA on the reproductive system, its interaction with pregnancy and effects on the fetus, discusses the management measures during pregnancy and the perinatal period in patients of childbearing age with TA, providing guidance for improving multidisciplinary management and clinical outcomes in these patients.

Key words: Takayasu arteritis, Pregnancy complications, Pregnancy, Hypertension, pregnancy-induced, Clinical governance, Review

摘要：

Takayasu动脉炎是一种慢性肉芽肿性血管炎，主要累及主动脉及其主要分支，引起血管狭窄、闭塞和动脉瘤形成，对育龄期妇女有重要影响。大多数研究表明Takayasu动脉炎患者在妊娠期间病情较为稳定，但其仍有可能导致妊娠并发症，如妊娠期高血压、先兆子痫、早产及胎儿宫内生长受限等。为了降低Takayasu动脉炎对孕产妇和胎儿的不利影响，在妊娠期间控制疾病活动是非常有意义的。本文就Takayasu动脉炎对生殖系统的影响、与妊娠的相互作用以及对胎儿的影响进行详细阐述，同时对妊娠期及围生期的管理措施进行探讨，为今后Takayasu动脉炎妊娠期患者改善临床结局、提供多学科管理措施提供一定的参考。

关键词: Takayasu动脉炎, 妊娠并发症, 妊娠, 高血压, 妊娠性, 临床管理, 综述

LIU Yinghong,YANG Xiaojuan. Recent Advances in Clinical Management of Takayasu's Arteritis in Pregnancy[J]. Chinese General Practice, 2023, 26(35): 4483-4486. DOI: 10.12114/j.issn.1007-9572.2022.0665.
刘颖宏,杨晓娟. Takayasu动脉炎妊娠期间临床管理的研究进展[J]. 中国全科医学, 2023, 26(35): 4483-4486. DOI: 10.12114/j.issn.1007-9572.2022.0665.

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