
Chinese General Practice ›› 2023, Vol. 26 ›› Issue (02): 154-159.DOI: 10.12114/j.issn.1007-9572.2022.0576
Special Issue: 高血压最新文章合辑; 脑健康最新研究合辑
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Received:2022-03-15
Revised:2022-08-15
Published:2023-01-15
Online:2022-08-31
Contact:
LI Qiujie
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通讯作者:
李秋洁
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URL: https://www.chinagp.net/EN/10.12114/j.issn.1007-9572.2022.0576
| 组别 | 例数 | 年龄( | 性别〔n(%)〕 | BMI( | 职业〔n(%)〕 | 婚姻状况〔n(%)〕 | ||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 男 | 女 | 轻体力劳动 | 中等体力劳动 | 重体力劳动 | 有配偶 | 无配偶(未婚、离异或丧偶) | ||||||
| N-MCI组 | 133 | 53.5±10.7 | 71(53.4) | 62(46.6) | 24.3±3.0 | 62(46.6) | 50(37.6) | 21(15.8) | 106(79.7) | 27(20.3) | ||
| MCI组 | 80 | 46.7±10.9 | 42(52.5) | 38(47.5) | 25.1±3.3 | 33(41.3) | 26(32.5) | 21(26.2) | 63(78.8) | 17(21.2) | ||
| 检验统计量值 | -4.471a | 0.016b | -1.999a | -2.502c | 0.027b | |||||||
| P值 | <0.001 | 0.900 | 0.047 | 0.012 | 0.868 | |||||||
| 组别 | 受教育程度〔n(%)〕 | 居住地〔n(%)〕 | 居住类型〔n(%)〕 | 家庭人均月收入〔n(%)〕 | ||||||||
| 初中及以下 | 高中 | 大专 | 本科及以上 | 农村 | 城市 | 独居 | 和家人 | <1 000元 | 1 001~3 000元 | 3 001~5 000元 | >5 000元 | |
| N-MCI组 | 24(18.0) | 47(35.3) | 36(27.1) | 26(19.6) | 87(65.4) | 46(34.6) | 38(28.6) | 95(71.4) | 5(3.8) | 54(40.6) | 57(42.9) | 17(12.7) |
| MCI组 | 34(42.5) | 32(40.0) | 10(12.5) | 4(5.0) | 39(48.8) | 41(51.2) | 31(38.7) | 49(61.3) | 8(10.0) | 45(56.2) | 26(32.5) | 1(1.3) |
| 检验统计量值 | -6.190c | 5.741b | 2.363b | -4.827c | ||||||||
| P值 | <0.001 | 0.017 | 0.124 | <0.001 | ||||||||
| 组别 | 吸烟史〔n(%)〕 | 饮酒史〔n(%)〕 | 高血压分级〔n(%)〕 | 合并糖尿病〔n(%)〕 | D型人格〔n(%)〕 | |||||||
| 是 | 否 | 是 | 否 | 1级 | 2级 | 3级 | 是 | 否 | 是 | 否 | ||
| N-MCI组 | 37(53.4) | 96(46.6) | 22(16.5) | 111(83.5) | 48(36.1) | 46(34.6) | 39(29.3) | 33(24.8) | 100(75.2) | 37(27.8) | 96(72.2) | |
| MCI组 | 44(55.0) | 36(45.0) | 22(27.5) | 58(72.5) | 11(13.7) | 24(30.0) | 45(56.3) | 28(35.0) | 52(65.0) | 43(53.7) | 37(46.3) | |
| 检验统计量值 | 15.659b | 3.660b | -4.751c | 2.537b | 14.322b | |||||||
| P值 | <0.001 | 0.056 | <0.001 | 0.111 | <0.001 | |||||||
| 组别 | 病程〔n(%)〕 | 空腹血糖( | TC( | TG( | HDL-C( | LDL-C( | WBC( | |||||
| 1~5年 | 6~10年 | >10年 | ||||||||||
| N-MCI组 | 75(67.6) | 34(48.6) | 24(75.0) | 5.92±1.69 | 4.28±1.01 | 1.64±0.80 | 1.19±0.34 | 2.59±0.85 | 6.77±1.76 | |||
| MCI组 | 36(32.4) | 36(51.4) | 8(25.0) | 6.20±1.83 | 4.31±0.97 | 2.27±1.77 | 0.97±0.28 | 2.51±0.83 | 7.04±1.76 | |||
| 检验统计量值 | -0.786c | -1.159a | 0.189a | -3.536a | 4.957a | 0.762a | -1.082a | |||||
| P值 | 0.432 | 0.248 | 0.851 | 0.001 | <0.001 | 0.447 | 0.281 | |||||
Table 1 Univariate analysis of influencing factors of mild cognitive impairment in young and middle-aged hospitalized patients with hypertension
| 组别 | 例数 | 年龄( | 性别〔n(%)〕 | BMI( | 职业〔n(%)〕 | 婚姻状况〔n(%)〕 | ||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 男 | 女 | 轻体力劳动 | 中等体力劳动 | 重体力劳动 | 有配偶 | 无配偶(未婚、离异或丧偶) | ||||||
| N-MCI组 | 133 | 53.5±10.7 | 71(53.4) | 62(46.6) | 24.3±3.0 | 62(46.6) | 50(37.6) | 21(15.8) | 106(79.7) | 27(20.3) | ||
| MCI组 | 80 | 46.7±10.9 | 42(52.5) | 38(47.5) | 25.1±3.3 | 33(41.3) | 26(32.5) | 21(26.2) | 63(78.8) | 17(21.2) | ||
| 检验统计量值 | -4.471a | 0.016b | -1.999a | -2.502c | 0.027b | |||||||
| P值 | <0.001 | 0.900 | 0.047 | 0.012 | 0.868 | |||||||
| 组别 | 受教育程度〔n(%)〕 | 居住地〔n(%)〕 | 居住类型〔n(%)〕 | 家庭人均月收入〔n(%)〕 | ||||||||
| 初中及以下 | 高中 | 大专 | 本科及以上 | 农村 | 城市 | 独居 | 和家人 | <1 000元 | 1 001~3 000元 | 3 001~5 000元 | >5 000元 | |
| N-MCI组 | 24(18.0) | 47(35.3) | 36(27.1) | 26(19.6) | 87(65.4) | 46(34.6) | 38(28.6) | 95(71.4) | 5(3.8) | 54(40.6) | 57(42.9) | 17(12.7) |
| MCI组 | 34(42.5) | 32(40.0) | 10(12.5) | 4(5.0) | 39(48.8) | 41(51.2) | 31(38.7) | 49(61.3) | 8(10.0) | 45(56.2) | 26(32.5) | 1(1.3) |
| 检验统计量值 | -6.190c | 5.741b | 2.363b | -4.827c | ||||||||
| P值 | <0.001 | 0.017 | 0.124 | <0.001 | ||||||||
| 组别 | 吸烟史〔n(%)〕 | 饮酒史〔n(%)〕 | 高血压分级〔n(%)〕 | 合并糖尿病〔n(%)〕 | D型人格〔n(%)〕 | |||||||
| 是 | 否 | 是 | 否 | 1级 | 2级 | 3级 | 是 | 否 | 是 | 否 | ||
| N-MCI组 | 37(53.4) | 96(46.6) | 22(16.5) | 111(83.5) | 48(36.1) | 46(34.6) | 39(29.3) | 33(24.8) | 100(75.2) | 37(27.8) | 96(72.2) | |
| MCI组 | 44(55.0) | 36(45.0) | 22(27.5) | 58(72.5) | 11(13.7) | 24(30.0) | 45(56.3) | 28(35.0) | 52(65.0) | 43(53.7) | 37(46.3) | |
| 检验统计量值 | 15.659b | 3.660b | -4.751c | 2.537b | 14.322b | |||||||
| P值 | <0.001 | 0.056 | <0.001 | 0.111 | <0.001 | |||||||
| 组别 | 病程〔n(%)〕 | 空腹血糖( | TC( | TG( | HDL-C( | LDL-C( | WBC( | |||||
| 1~5年 | 6~10年 | >10年 | ||||||||||
| N-MCI组 | 75(67.6) | 34(48.6) | 24(75.0) | 5.92±1.69 | 4.28±1.01 | 1.64±0.80 | 1.19±0.34 | 2.59±0.85 | 6.77±1.76 | |||
| MCI组 | 36(32.4) | 36(51.4) | 8(25.0) | 6.20±1.83 | 4.31±0.97 | 2.27±1.77 | 0.97±0.28 | 2.51±0.83 | 7.04±1.76 | |||
| 检验统计量值 | -0.786c | -1.159a | 0.189a | -3.536a | 4.957a | 0.762a | -1.082a | |||||
| P值 | 0.432 | 0.248 | 0.851 | 0.001 | <0.001 | 0.447 | 0.281 | |||||
| 自变量 | 赋值 |
|---|---|
| 职业 | 轻体力劳动=1,中等体力劳动=2,重体力劳动=3 |
| 受教育程度 | 初中及以下=1,高中=2,大专=3,本科及以上=4 |
| 居住地 | 城市=0,农村=1 |
| 家庭人均月收入 | <1 000元=1,1 001~3 000元=2,3 001~5 000元=3,>5 000元=4 |
| 吸烟史 | 无=0,有=1 |
| 高血压分级 | 1级=1,2级=2,3级=3 |
| D型人格 | 否=0,是=1 |
Table 2 Assignment for influencing factors of mild cognitive impairment in young and middle-aged hospitalized patients with hypertension analyzed using multiple Logistic regression analysis
| 自变量 | 赋值 |
|---|---|
| 职业 | 轻体力劳动=1,中等体力劳动=2,重体力劳动=3 |
| 受教育程度 | 初中及以下=1,高中=2,大专=3,本科及以上=4 |
| 居住地 | 城市=0,农村=1 |
| 家庭人均月收入 | <1 000元=1,1 001~3 000元=2,3 001~5 000元=3,>5 000元=4 |
| 吸烟史 | 无=0,有=1 |
| 高血压分级 | 1级=1,2级=2,3级=3 |
| D型人格 | 否=0,是=1 |
| 自变量 | 偏回归系数 | 标准误差 | Wald χ2值 | P值 | OR值 | 95%CI | |
|---|---|---|---|---|---|---|---|
| 年龄 | 0.069 | 0.020 | 12.342 | <0.001 | 1.073 | (1.033,1.115) | |
| BMI | 0.030 | 0.065 | 0.218 | 0.640 | 1.031 | (0.908,1.170) | |
| 职业(以轻体力劳动为参照) | |||||||
| 中等体力劳动 | -0.348 | 0.443 | 0.618 | 0.432 | 0.706 | (0.296,1.681) | |
| 重体力劳动 | 0.291 | 0.544 | 0.287 | 0.592 | 1.338 | (0.461,3.885) | |
| 受教育程度(以初中及以下为参照) | |||||||
| 高中 | -0.401 | 0.467 | 0.738 | 0.390 | 0.669 | (0.268,1.672) | |
| 大专 | -1.281 | 0.611 | 4.397 | 0.036 | 0.278 | (0.084,0.920) | |
| 本科及以上 | -1.210 | 0.829 | 2.134 | 0.144 | 0.298 | (0.059,1.512) | |
| 居住地(以城市为参照) | |||||||
| 农村 | 0.263 | 0.439 | 0.359 | 0.549 | 1.301 | (0.550,3.073) | |
| 家庭人均月收入(以<1 000元为参照) | |||||||
| 1 001~3 000元 | -0.715 | 0.813 | 0.773 | 0.379 | 0.489 | (0.099,2408) | |
| 3 001~5 000元 | -0.356 | 0.863 | 0.170 | 0.680 | 0.701 | (0.129,3.802) | |
| >5 000元 | -1.790 | 1.442 | 1.542 | 0.214 | 0.167 | (0.010,2.817) | |
| 吸烟史(以无为参照) | |||||||
| 有 | 0.914 | 0.397 | 5.306 | 0.021 | 2.494 | (1.146,5.426) | |
| 高血压分级(以1级为参照) | |||||||
| 2级 | 1.236 | 0.516 | 5.734 | 0.017 | 3.442 | (1.252,9.468) | |
| 3级 | 1.370 | 0.486 | 7.947 | 0.005 | 3.934 | (1.518,10.193) | |
| D型人格(以否为参照) | |||||||
| 是 | 0.770 | 0.385 | 3.995 | 0.046 | 2.160 | (1.015,4.598) | |
| TG | 0.468 | 0.178 | 6.869 | 0.009 | 1.596 | (1.125,2.265) | |
| HDL-C | -1.685 | 0.683 | 6.093 | 0.014 | 0.185 | (0.049,0.707) | |
Table 3 Multiple Logistic regression analysis of influencing factors of mild cognitive impairment in young and middle-aged hospitalized patients with hypertension
| 自变量 | 偏回归系数 | 标准误差 | Wald χ2值 | P值 | OR值 | 95%CI | |
|---|---|---|---|---|---|---|---|
| 年龄 | 0.069 | 0.020 | 12.342 | <0.001 | 1.073 | (1.033,1.115) | |
| BMI | 0.030 | 0.065 | 0.218 | 0.640 | 1.031 | (0.908,1.170) | |
| 职业(以轻体力劳动为参照) | |||||||
| 中等体力劳动 | -0.348 | 0.443 | 0.618 | 0.432 | 0.706 | (0.296,1.681) | |
| 重体力劳动 | 0.291 | 0.544 | 0.287 | 0.592 | 1.338 | (0.461,3.885) | |
| 受教育程度(以初中及以下为参照) | |||||||
| 高中 | -0.401 | 0.467 | 0.738 | 0.390 | 0.669 | (0.268,1.672) | |
| 大专 | -1.281 | 0.611 | 4.397 | 0.036 | 0.278 | (0.084,0.920) | |
| 本科及以上 | -1.210 | 0.829 | 2.134 | 0.144 | 0.298 | (0.059,1.512) | |
| 居住地(以城市为参照) | |||||||
| 农村 | 0.263 | 0.439 | 0.359 | 0.549 | 1.301 | (0.550,3.073) | |
| 家庭人均月收入(以<1 000元为参照) | |||||||
| 1 001~3 000元 | -0.715 | 0.813 | 0.773 | 0.379 | 0.489 | (0.099,2408) | |
| 3 001~5 000元 | -0.356 | 0.863 | 0.170 | 0.680 | 0.701 | (0.129,3.802) | |
| >5 000元 | -1.790 | 1.442 | 1.542 | 0.214 | 0.167 | (0.010,2.817) | |
| 吸烟史(以无为参照) | |||||||
| 有 | 0.914 | 0.397 | 5.306 | 0.021 | 2.494 | (1.146,5.426) | |
| 高血压分级(以1级为参照) | |||||||
| 2级 | 1.236 | 0.516 | 5.734 | 0.017 | 3.442 | (1.252,9.468) | |
| 3级 | 1.370 | 0.486 | 7.947 | 0.005 | 3.934 | (1.518,10.193) | |
| D型人格(以否为参照) | |||||||
| 是 | 0.770 | 0.385 | 3.995 | 0.046 | 2.160 | (1.015,4.598) | |
| TG | 0.468 | 0.178 | 6.869 | 0.009 | 1.596 | (1.125,2.265) | |
| HDL-C | -1.685 | 0.683 | 6.093 | 0.014 | 0.185 | (0.049,0.707) | |
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Abstract |
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