
Chinese General Practice ›› 2022, Vol. 25 ›› Issue (36): 4522-4527.DOI: 10.12114/j.issn.1007-9572.2022.0402
Special Issue: 心血管最新文章合辑
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Received:2022-03-06
Revised:2022-08-15
Published:2022-12-20
Online:2022-09-15
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WU Xinhua
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通讯作者:
吴新华
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URL: https://www.chinagp.net/EN/10.12114/j.issn.1007-9572.2022.0402
| 海拔 | 例数 | 年龄(岁) | SBP (mm Hg) | DBP (mm Hg) | FPG (mmol/L) | TG〔M(P25,P75),mmol/L〕 | TC (mmol/L) | LDL-C〔M(P25,P75),mmol/L〕 | HDL-C (mmol/L) | BMI (kg/m2) |
|---|---|---|---|---|---|---|---|---|---|---|
| 中等海拔高原地区 | 189 | 53.9±9.3 | 136±26 | 82±15 | 5.30±1.26 | 1.15(0.88,1.54) | 5.43±1.12 | 3.11(2.59,3.66) | 1.57±0.50 | 22.7±3.5 |
| 高海拔高原地区 | 192 | 53.5±9.0 | 142±22 | 84±13 | 5.01±0.90 | 1.41(1.07,1.82) | 5.19±1.17 | 2.78(2.29,3.57) | 1.54±0.41 | 22.6±3.4 |
| t(Z)值 | -0.48 | 2.71 | 1.56 | -2.62 | -3.81a | -2.06 | -3.24a | -0.62 | -0.14 | |
| P值 | 0.630 | 0.007 | 0.120 | 0.009 | <0.001 | 0.041 | 0.001 | 0.534 | 0.887 |
Table 1 Comparison of baseline data of rural Naxi population in low-to-high altitudes
| 海拔 | 例数 | 年龄(岁) | SBP (mm Hg) | DBP (mm Hg) | FPG (mmol/L) | TG〔M(P25,P75),mmol/L〕 | TC (mmol/L) | LDL-C〔M(P25,P75),mmol/L〕 | HDL-C (mmol/L) | BMI (kg/m2) |
|---|---|---|---|---|---|---|---|---|---|---|
| 中等海拔高原地区 | 189 | 53.9±9.3 | 136±26 | 82±15 | 5.30±1.26 | 1.15(0.88,1.54) | 5.43±1.12 | 3.11(2.59,3.66) | 1.57±0.50 | 22.7±3.5 |
| 高海拔高原地区 | 192 | 53.5±9.0 | 142±22 | 84±13 | 5.01±0.90 | 1.41(1.07,1.82) | 5.19±1.17 | 2.78(2.29,3.57) | 1.54±0.41 | 22.6±3.4 |
| t(Z)值 | -0.48 | 2.71 | 1.56 | -2.62 | -3.81a | -2.06 | -3.24a | -0.62 | -0.14 | |
| P值 | 0.630 | 0.007 | 0.120 | 0.009 | <0.001 | 0.041 | 0.001 | 0.534 | 0.887 |
| 性别 | 例数 | 高血压 | 糖尿病 | 吸烟 | 血脂异常 | 体质量异常 |
|---|---|---|---|---|---|---|
| 男 | 147 | 69(46.9) | 9(6.1) | 89(60.5) | 91(61.9) | 45(30.6) |
| 女 | 234 | 117(50.0) | 9(3.8) | 5(2.1) | 129(55.1) | 66(28.2) |
| χ2值 | 0.34 | 1.04 | 165.72 | 1.70 | 0.25 | |
| P值 | 0.561 | 0.308 | <0.001 | 0.192 | 0.615 |
Table 2 Exposure to major ICVD risk factors of diferent gender in rural Naxi population
| 性别 | 例数 | 高血压 | 糖尿病 | 吸烟 | 血脂异常 | 体质量异常 |
|---|---|---|---|---|---|---|
| 男 | 147 | 69(46.9) | 9(6.1) | 89(60.5) | 91(61.9) | 45(30.6) |
| 女 | 234 | 117(50.0) | 9(3.8) | 5(2.1) | 129(55.1) | 66(28.2) |
| χ2值 | 0.34 | 1.04 | 165.72 | 1.70 | 0.25 | |
| P值 | 0.561 | 0.308 | <0.001 | 0.192 | 0.615 |
| 年龄(岁) | 例数 | 高血压 | 糖尿病 | 吸烟 | 血脂异常 | 体质量异常 |
|---|---|---|---|---|---|---|
| 35~ | 11 | 3(27.3) | 0 | 3(27.3) | 4(36.4) | 4(36.4) |
| 40~ | 51 | 15(29.4) | 1(2.0) | 10(19.6) | 24(47.1) | 21(41.2) |
| 45~ | 79 | 26(32.9) | 2(2.5) | 22(27.8) | 46(58.2) | 24(30.4) |
| 50~ | 81 | 40(49.4) | 6(7.4) | 17(21.0) | 50(61.7) | 26(32.1) |
| 55~ | 61 | 36(59.0) | 3(4.9) | 16(26.2) | 33(54.1) | 20(32.6) |
| 60~ | 30 | 22(73.3) | 2(6.7) | 7(23.3) | 22(73.3) | 6(20.0) |
| 65~ | 44 | 28(63.6) | 1(2.3) | 13(29.5) | 26(59.1) | 5(11.4) |
| 70~75 | 24 | 16(66.7) | 3(12.5) | 6(25.0) | 15(62.5) | 5(20.8) |
| χ2趋势值 | 29.06 | 2.31 | 0.31 | 3.04 | 9.45 | |
| P值 | <0.001 | 0.130 | 0.580 | 0.080 | <0.001 |
Table 3 Exposure to major ICVD risk factors of diferent age in rural Naxi population
| 年龄(岁) | 例数 | 高血压 | 糖尿病 | 吸烟 | 血脂异常 | 体质量异常 |
|---|---|---|---|---|---|---|
| 35~ | 11 | 3(27.3) | 0 | 3(27.3) | 4(36.4) | 4(36.4) |
| 40~ | 51 | 15(29.4) | 1(2.0) | 10(19.6) | 24(47.1) | 21(41.2) |
| 45~ | 79 | 26(32.9) | 2(2.5) | 22(27.8) | 46(58.2) | 24(30.4) |
| 50~ | 81 | 40(49.4) | 6(7.4) | 17(21.0) | 50(61.7) | 26(32.1) |
| 55~ | 61 | 36(59.0) | 3(4.9) | 16(26.2) | 33(54.1) | 20(32.6) |
| 60~ | 30 | 22(73.3) | 2(6.7) | 7(23.3) | 22(73.3) | 6(20.0) |
| 65~ | 44 | 28(63.6) | 1(2.3) | 13(29.5) | 26(59.1) | 5(11.4) |
| 70~75 | 24 | 16(66.7) | 3(12.5) | 6(25.0) | 15(62.5) | 5(20.8) |
| χ2趋势值 | 29.06 | 2.31 | 0.31 | 3.04 | 9.45 | |
| P值 | <0.001 | 0.130 | 0.580 | 0.080 | <0.001 |
| 海拔 | 例数 | 高血压 | 糖尿病 | 吸烟 | 血脂异常 | 体质量异常 |
|---|---|---|---|---|---|---|
| 中等海拔高原地区 | 189 | 80(42.3) | 13(6.9) | 50(26.5) | 106(56.1) | 50(26.5) |
| 高海拔高原地区 | 192 | 106(55.2) | 5(2.6) | 44(22.9) | 114(59.4) | 61(31.8) |
| χ2值 | 6.32 | 3.87 | 0.64 | 0.42 | 1.30 | |
| P值 | 0.012 | 0.049 | 0.423 | 0.516 | 0.254 |
Table 4 Exposure to major ICVD risk factors of rural Naxi population in low-to-high altitudes
| 海拔 | 例数 | 高血压 | 糖尿病 | 吸烟 | 血脂异常 | 体质量异常 |
|---|---|---|---|---|---|---|
| 中等海拔高原地区 | 189 | 80(42.3) | 13(6.9) | 50(26.5) | 106(56.1) | 50(26.5) |
| 高海拔高原地区 | 192 | 106(55.2) | 5(2.6) | 44(22.9) | 114(59.4) | 61(31.8) |
| χ2值 | 6.32 | 3.87 | 0.64 | 0.42 | 1.30 | |
| P值 | 0.012 | 0.049 | 0.423 | 0.516 | 0.254 |
| 项目 | 例数 | 0个主要危险因素 | 1个主要危险因素 | 2个主要危险因素 | ≥3个主要危险因素 | χ2值 | P值 | |
|---|---|---|---|---|---|---|---|---|
| 性别 | 31.84 | <0.001 | ||||||
| 男 | 147 | 11(7.5) | 33(22.4) | 53(36.1) | 50(34.0) | |||
| 女 | 234 | 49(20.9) | 78(33.3) | 75(32.1) | 32(13.7) | |||
| 年龄(岁) | 5.69 | 0.017 | ||||||
| 35~ | 62 | 13(21.0) | 25(40.3) | 14(22.6) | 10(16.1) | |||
| 45~ | 160 | 24(15.0) | 50(31.3) | 55(34.4) | 31(19.4) | |||
| 55~ | 91 | 15(16.5) | 17(18.7) | 33(36.3) | 26(28.6) | |||
| 65~75 | 68 | 8(11.8) | 19(27.9) | 26(38.2) | 15(22.1) | |||
| 海拔 | 4.71 | 0.194 | ||||||
| 中等海拔 | 189 | 32(16.9) | 63(33.3) | 56(29.8) | 38(20.1) | |||
| 高海拔 | 192 | 28(14.6) | 48(25.0) | 72(37.5) | 44(22.9) | |||
Table 5 Distribution of main ICVD risk factors in rural Naxi population
| 项目 | 例数 | 0个主要危险因素 | 1个主要危险因素 | 2个主要危险因素 | ≥3个主要危险因素 | χ2值 | P值 | |
|---|---|---|---|---|---|---|---|---|
| 性别 | 31.84 | <0.001 | ||||||
| 男 | 147 | 11(7.5) | 33(22.4) | 53(36.1) | 50(34.0) | |||
| 女 | 234 | 49(20.9) | 78(33.3) | 75(32.1) | 32(13.7) | |||
| 年龄(岁) | 5.69 | 0.017 | ||||||
| 35~ | 62 | 13(21.0) | 25(40.3) | 14(22.6) | 10(16.1) | |||
| 45~ | 160 | 24(15.0) | 50(31.3) | 55(34.4) | 31(19.4) | |||
| 55~ | 91 | 15(16.5) | 17(18.7) | 33(36.3) | 26(28.6) | |||
| 65~75 | 68 | 8(11.8) | 19(27.9) | 26(38.2) | 15(22.1) | |||
| 海拔 | 4.71 | 0.194 | ||||||
| 中等海拔 | 189 | 32(16.9) | 63(33.3) | 56(29.8) | 38(20.1) | |||
| 高海拔 | 192 | 28(14.6) | 48(25.0) | 72(37.5) | 44(22.9) | |||
| 年龄(岁) | 例数(男/女) | 男性 | 女性 | Z值 | P值 |
|---|---|---|---|---|---|
| 35~ | 4/7 | 1.2(0.6,5.9) | 0.2(0.2,0.5) | 1.5 | 0.015 |
| 40~ | 19/32 | 1.5(0.6,2.1) | 0.5(0.3,1.1) | 138.0 | 0.001 |
| 45~ | 26/53 | 2.1(1.1,2.9) | 1.2(0.5,1.8) | 326.0 | <0.001 |
| 50~ | 33/48 | 2.1(2.1,5.4) | 1.8(1.2,4.4) | 567.0 | 0.030 |
| 55~ | 30/31 | 3.9(2.7,7.9) | 4.4(1.8,6.8) | 406.0 | 0.393 |
| 60~ | 7/23 | 7.3(3.9,19.5) | 6.8(4.4,15.6) | 72.0 | 0.675 |
| 65~ | 20/24 | 8.5(3.9,19.5) | 8.55(4.4,15.6) | 236.0 | 0.925 |
| 70~75 | 8/16 | 12.8(7.3,19.5) | 12.95(2.8,23.0) | 60.0 | 0.805 |
| 合计 | 147/234 | 2.9(2.1,7.3) | 1.8(0.8,6.8) | 13 132.0 | <0.001 |
Table 6 The absolute 10-year risk of ICVD assessed using Modified 10-year ICVD Risk Scale in Chinese Adults in rural Naxi population by sex and age
| 年龄(岁) | 例数(男/女) | 男性 | 女性 | Z值 | P值 |
|---|---|---|---|---|---|
| 35~ | 4/7 | 1.2(0.6,5.9) | 0.2(0.2,0.5) | 1.5 | 0.015 |
| 40~ | 19/32 | 1.5(0.6,2.1) | 0.5(0.3,1.1) | 138.0 | 0.001 |
| 45~ | 26/53 | 2.1(1.1,2.9) | 1.2(0.5,1.8) | 326.0 | <0.001 |
| 50~ | 33/48 | 2.1(2.1,5.4) | 1.8(1.2,4.4) | 567.0 | 0.030 |
| 55~ | 30/31 | 3.9(2.7,7.9) | 4.4(1.8,6.8) | 406.0 | 0.393 |
| 60~ | 7/23 | 7.3(3.9,19.5) | 6.8(4.4,15.6) | 72.0 | 0.675 |
| 65~ | 20/24 | 8.5(3.9,19.5) | 8.55(4.4,15.6) | 236.0 | 0.925 |
| 70~75 | 8/16 | 12.8(7.3,19.5) | 12.95(2.8,23.0) | 60.0 | 0.805 |
| 合计 | 147/234 | 2.9(2.1,7.3) | 1.8(0.8,6.8) | 13 132.0 | <0.001 |
| [1] |
|
| [2] |
中国心血管健康与疾病报告编写组. 中国心血管健康与疾病报告2019概要[J]. 中国循环杂志,2020,35(9):833-854. DOI:10.3969/j.issn.1000-3614.2020.09.001.
|
| [3] |
吴新华,陈章荣,刘宏,等. 跨高原心血管疾病研究进展[J]. 大理大学学报,2019,4(10):71-74.
|
| [4] |
国家"十五"攻关"冠心病、脑卒中综合危险度评估及干预方案的研究"课题组. 国人缺血性心血管病发病危险的评估方法及简易评估工具的开发研究[J]. 中华心血管病杂志,2003,31(12):893-901. DOI:10.3760/j:issn:0253-3758.2003.12.005.
|
| [5] |
|
| [6] | |
| [7] |
中华医学会糖尿病学分会. 中国2型糖尿病防治指南(2017年版)[J]. 中华糖尿病杂志,2018,10 (1):4-67. DOI:10.3760/cma.j.issn.1674-5809.2018.01.003.
|
| [8] |
中国成人血脂异常防治指南制订联合委员会. 中国成人血脂异常防治指南[J]. 中华心血管病杂志,2007,35(5):390-419. DOI:10.3760/j.issn:0253-3758.2007.05.003.
|
| [9] |
严青华,张夏芸,徐继英,等. 上海市35~59岁人群缺血性心血管病10年发病风险评估[J]. 中国公共卫生,2019,35(9):1183-1186. DOI:10.11847/zgggws1122521.
|
| [10] |
刘览,刘华章,冯颖青,等. 广州市35~75岁社区居民心血管病主要危险因素聚集情况分析[J]. 现代预防医学,2020,47(4):635-639,647.
|
| [11] |
|
| [12] |
|
| [13] |
|
| [14] |
|
| [15] |
|
| [16] |
|
| [17] |
赵菁华,刘琳,周瑶,等. 不同海拔地区藏族就诊人群血脂、血液黏度、HCY水平与心血管疾病的相关性研究[J]. 现代生物医学进展,2019,19(12):2311-2315. DOI:10.13241/j.cnki.pmb.2019.12.024.
|
| [18] |
|
| [19] |
|
| [20] |
|
| [21] |
|
| [22] |
马爱娟,董忠. 北京市35~59岁人群缺血性心血管病10年发病危险预测[J]. 中国慢性病预防与控制,2018,26(8):593-597. DOI:10.16386/j.cjpccd.issn.1004-6194.2018.08.008.
|
| [23] |
黄山,张秋,钟鑫,等. 广西壮族农村成年人群缺血性心血管病10年发病风险调查及危险因素分析[J]. 广西医科大学学报,2021,38(4):821-827. DOI:10.16190/j.cnki.45-1211/r.2021.04.033.
|
| [24] |
|
| [25] |
|
| [26] |
赵莹颖,何朝,张艳艳,等. 北京市顺义区35~59岁社区居民缺血性心血管病发病危险评估[J]. 中国慢性病预防与控制,2016,24(5):356-358. DOI:10.16386/j.cjpccd.issn.1004-6194.2016.05.011.
|
| [27] |
张梅,黄正京,李镒冲,等. 中国35岁及以上人群缺血性心血管病10年发病风险预测[J]. 中华流行病学杂志,2016,37(5):689-693.
|
| [28] |
|
| [29] |
|
| [30] |
|
| [31] |
|
| [32] |
|
| [33] |
|
| [34] |
|
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