China has a large baseline number of patients with hepatitis B virus (HBV) -related chronic liver disease, and it is urgently to contain HBV infection prevalence. To do this, the issue that needs to be addressed quickly is transforming the hospital-based management into community-, hospital-, patient- and society-based management.

To quantify preferences of health management in patients with HBV-related chronic liver disease from Hubei Province, providing a basis for the development of strategies for containing chronic hepatitis disease and for managing such patients.

From July 2018 to July 2019, a discrete choice experiment survey was carried out with a multistage random sample of 180 patients with HBV-related chronic liver disease recruited from three cities (Wuhan, Shiyan, and Xiangyang) of Hubei Province using a questionnaire for collecting their general information, and preferences related to health management (choice sets in the discrete choice experiment consist of place for regular health checkups, average monthly expense for health management of HBV-related chronic liver disease, followed health management, and ways of accessing health management information of HBV-related chronic liver disease with different options) . The mixed Logit model developed in 15.0 was used for data analysis.

The response rate of the survey was 89.4% (161/180) . Patients were more tended to choose a management pattern with lower average monthly expense, a hospital as the place for regular medical examinations, self-management or accessing health management information using offline approaches (P<0.05) . The amount of an additional monthly expense that the patients were willing to pay was 256.75 yuan if the place for regular health checkups was changed to a hospital from a community, 96.87 yuan if the management pattern was changed to self-management from a patient support group-based management, and 52.94 yuan if the approaches for accessing health management information were changed to offline from online. Compared with other choices, the change in the place for regular health checkups from a community to a hospital was the most popular in the patients (willingness increased by 87.29%) .

Patients with HBV-related chronic liver disease preferred to undergo regular health checkups and access health management information in hospitals, but were less likely to contract a family doctor or invest in health. To improve the containment of chronic liver disease, we put forward the following recommendations: strengthening hospitals' capabilities in treating HBV-related chronic liver disease, and their services delivered by a family doctor team, guiding patients to change the idea of "focusing on treatment rather than prevention", and delivering integrated online and offline services.

我国慢性乙型肝炎（简称慢性乙肝）及相关疾病患者基数较大，遏制乙型肝炎病毒（HBV）继续流行迫在眉睫。如何将慢性乙型的管理模式从单纯医疗机构治疗转变为社区、医疗机构、患者、社会相关组织等共同参与，成为慢性乙肝健康管理亟待解决的问题。

通过量化湖北省慢性乙肝及相关疾病患者的健康管理选择偏好，为慢性乙型防控策略和患者健康管理提供依据。

2018年7月至2019年7月，基于离散选择实验设计，采用多阶段随机抽样方法，抽取湖北省武汉市、十堰市、襄阳市的180例慢性乙肝及相关疾病患者进行问卷调查，问卷包括调查对象基本信息、离散选择实验选择集（共包括定期检查地点、月均支付费用、依从性管理模式、信息获取渠道4个属性，每个属性又包括若干水平）。运用Stata 15.0构建混合Logit模型进行数据分析。

回收有效问卷161份，问卷有效回收率为89.4%。湖北省慢性乙肝及相关疾病患者更倾向选择定期检查地点为医院、月均支付费用低、自我管理及线下获取信息的健康管理模式（P<0.05）。当定期检查地点从社区转变为医院时，慢性乙肝及相关疾病患者愿意支付的费用增加256.75元；当依从性管理模式从自我管理转变为病友互助小组、信息获取渠道从线下转变为线上时，患者愿意支付的费用分别减少96.87、52.94元。在不同政策干预下，当定期检查地点从社区转变为医院时，乙肝及相关疾病患者的选择意愿最强（意愿提高87.29%）。

慢性乙肝及相关疾病患者更偏好在医院定期检查和获取相关信息，签约家庭医生团队及投资健康的意愿均不强。建议在加强医院慢性乙肝疾病救治服务能力的同时，通过做实家庭医生团队服务，引导患者改变"重治轻防"观念，采取线上、线下融合服务措施，提升慢性乙肝及相关疾病防控成效。