Chronic obstructive pulmonary disease (COPD) is associated with a substantial disease burden. The attributes of different treatment options vary, which can affect patient adherence and, consequently, treatment outcomes. Discrete choice experiment (DCE) can identify the key factors (attributes) influencing patient choices, determine the most valued attributes, and quantify the trade-offs between attributes. DCEs have been widely applied in the healthcare field.

To review and evaluate the literature on DCE regarding treatment and device preferences among patients with COPD, with the aim of providing a reference for conducting health preference-related research on COPD patients in China.

Literature utilizing DCEs to measure health preferences among patients with COPD was retrieved from the Web of Science Core Collection, PubMed, CNKI, Wanfang Data, CBM, and VIP Database. The PREFS checklist was employed for quality evaluation. The attributes in the studies and their corresponding dimensions were analyzed and discussed.

A total of 11 studies were included, all from developed countries. Significant differences were observed in the attributes due to variations in research objectives and subjects. Regarding treatment preferences, the proportions of attributes related to efficacy, convenience, treatment burden, risk, and patient characteristics were 29%, 29%, 20%, 11%, and 11%, respectively. Patients with COPD particularly preferred attributes related to efficacy and risk dimensions, followed by treatment burden and patient characteristics, with less emphasis on convenience. For device preferences, the proportions of attributes related to feature design, device usage, and drug-related features were 36%, 32%, and 32%. COPD patients showed a strong preference for attributes related to device design and drug related features, followed by device use. The overall quality of the literature was not relatively high.

There is a discrepancy between the frequency of attributes included in each dimension and the dimensions preferred by patients, particularly with the convenience dimension being the least preferred in treatments. To date, there is no application of DCEs among COPD patients in China. In the future, more relevant research should be carried out based on the actual situation in China to provide evidence for the improvement of COPD treatment.

慢性阻塞性肺疾病（COPD）疾病负担沉重，不同治疗方案的属性不同，影响患者的依从性，进而影响治疗效果，离散选择试验既能确定影响患者选择的重要因素（属性），又能确定患者最为看重的属性，以及各属性间的权衡程度，已广泛应用于医药卫生领域。

回顾与评估离散选择试验在COPD患者对治疗与装置偏好研究文献，以期为国内开展COPD患者健康偏好相关研究提供参考。

在Web of Science、PubMed、中国知网、维普网、中国生物医学文献数据库、万方数据知识服务平台检索利用离散选择试验测量COPD患者健康偏好的文献，使用PREFS评估清单进行文献质量评估，对研究中出现属性及所属维度进行分析讨论。

最终纳入11篇文献，均来自欧美发达国家，属性的设定因研究目的及对象的不同而存在显著差异。针对治疗偏好，疗效、便利性、治疗负担、风险和患者特征包含属性的数量分别占29%、29%、20%、11%和11%，COPD患者尤为偏好疗效和风险维度的属性，其次是治疗负担和患者特征，便利性维度关注度较低；针对吸入装置偏好，特征设计、装置使用和药物搭配包含属性的数量分别占36%、32%和32%，COPD患者尤为偏好特征设计与药物搭配维度的属性，其次是装置使用，文献质量相对一般。

各维度的纳入属性频率与患者最为偏好的维度之间不呈正比，尤其是治疗方案中对便利性维度的偏好最低；目前我国仍未有离散选择试验在COPD中的应用研究，今后应立足我国实际开展更多相关研究，为COPD治疗的改善提供依据。