Recent Developments in Oral Frailty in the Elderly

doi:10.12114/j.issn.1007-9572.2022.0268

Chinese General Practice ›› 2022, Vol. 25 ›› Issue (36): 4582-4587.DOI: 10.12114/j.issn.1007-9572.2022.0268

• Review • Previous Articles Next Articles

Recent Developments in Oral Frailty in the Elderly

1.School of Nursing and Health, Zhengzhou University, Zhengzhou 450000, China
2.Education and Training Department, Henan Provincial People's Hospital, Zhengzhou 450000, China
3.Orthopedic Department, Henan Provincial People's Hospital, Zhengzhou 450000, China
4.School of Nursing and Health, Henan University, Kaifeng 475000, China

Received:2022-03-10 Revised:2022-05-06 Published:2022-12-20 Online:2022-06-02
Contact: DAI Fumin
About author:
PAN Q, DAI F M, PAN W Y, et al. Recent developments in oral frailty in the elderly [J] . Chinese General Practice, 2022, 25 (36) : 4582-4587.

老年人口腔衰弱的研究进展

1.450000　河南省郑州市，郑州大学护理与健康学院
2.450000　河南省郑州市，河南省人民医院教育培训处
3.450000　河南省郑州市，河南省人民医院骨科
4.475000　河南省开封市，河南大学护理与健康学院

通讯作者: 戴付敏
作者简介:
潘琦，戴付敏，潘卫宇，等.老年人口腔衰弱的研究进展[J].中国全科医学，2022，25（36）：4582-4587.[www.chinagp.net] 作者贡献：潘琦负责文章的构思和设计，文献资料收集及整理，撰写论文；戴付敏负责文章的可行性分析及质量控制，对文章整体负责，监督管理；潘卫宇负责文章的可行性分析及论文修订；刘佳敏、陈若娟进行文献收集，中英文论文修订。
基金资助:
河南省医学科技攻关计划省部共建项目(SB201901069)

Abstract

Abstract:

Oral frailty has been recently suggested as a novel construct defined as a decrease in oral function with a coexisting decline in cognitive and physical functions, which is associated with many adverse events in older adults, such as frailty, sarcopenia, disability, and mortality. We reviewed the definition, symptoms, diagnosis criteria, assessment tools of oral frailty in older people, and summarized its recent research status as well as possible influencing factors, then suggested that future research on oral frailty in older Chinese adults could be carried out in aspects involving developing oral frailty assessment tools appropriate for older Chinese people, implementing survey studies on oral frailty, enriching study designs and contents and enhancing oral frailty intervention studies.

Key words: Frailty, Aged, Oral frailty, Oral health, Oral and Maxillofacial Frailty Index, Root cause analysis, Review

摘要：

口腔衰弱作为一个新概念在衰弱领域被提出，指伴随认知及身体功能衰退的口腔功能低下，与衰弱、肌少症、残疾及死亡等诸多老年人不良事件有关。本文回顾分析了口腔衰弱的定义、临床特征及诊断标准，对口腔衰弱的研究现状、评估工具及相关影响因素进行归纳总结，提出老年人口腔衰弱未来的研究方向可结合我国实际情况从开发适合我国老年人口腔衰弱的评估工具、开展口腔衰弱的调查性研究、丰富研究设计内容和方法以及加强干预研究四方面开展。

关键词: 衰弱, 老年人, 口腔衰弱, 口腔保健, 口腔颌面衰弱指数, 影响因素分析, 综述

PAN Qi,DAI Fumin,PAN Weiyu, et al. Recent Developments in Oral Frailty in the Elderly[J]. Chinese General Practice, 2022, 25(36): 4582-4587. DOI: 10.12114/j.issn.1007-9572.2022.0268.
潘琦,戴付敏,潘卫宇等. 老年人口腔衰弱的研究进展[J]. 中国全科医学, 2022, 25(36): 4582-4587. DOI: 10.12114/j.issn.1007-9572.2022.0268.

References 41

[1]	国家统计局. 第七次全国人口普查[EB/OL]. （2021-09-07）[2021.10.22].
[2]	陈艳玫，刘子锋，李贤德，等. 2015—2050年中国人口老龄化趋势与老年人口预测[J]. 中国社会医学杂志，2018，35(5):480-483. DOI：10.3969/j.issn.1673-5625.2018.05.013.
[3]	王湾湾，李园园，石小天，等. 营养对衰弱影响的研究进展[J]. 中国全科医学，2021，24(6):673-677. DOI：10.12114/j.issn.1007-9572.2020.00.627.
[4]	HE B, MA Y, WANG C, et al. Prevalence and risk factors for frailty among community-dwelling older people in China：a systematic review and meta-analysis[J]. J Nutr Health Aging，2019，23(5):442-450. DOI：10.1007/s12603-019-1179-9.
[5]	HAKEEM F F, BERNABÉ E, SABBAH W. Association between oral health and frailty：a systematic review of longitudinal studies[J]. Gerodontology，2019，36(3):205-215. DOI：10.1111/ger.12406.
[6]	SLASHCHEVA L D, KARJALAHTI E, HASSETT L C, et al. A systematic review and gap analysis of frailty and oral health characteristics in older adults：a call for clinical translation[J]. Gerodontology，2021，38(4):338-350. DOI：10.1111/ger.12577.
[7]	SHIRAISHI A, WAKABAYASHI H, YOSHIMURA Y. Oral management in rehabilitation medicine：oral frailty，oral sarcopenia，and hospital-associated oral problems[J]. J Nutr Health Aging，2020，24(10):1094-1099. DOI：10.1007/s12603-020-1439-8.
[8]	MORLEY J E. ORAL FRAILTY[J]. J Nutr Health Aging，2020，24(7):683-684. DOI：10.1007/s12603-020-1438-9.
[9]	SEMBA R D, BLAUM C S, BARTALI B, et al. Denture use，malnutrition，frailty，and mortality among older women living in the community[J]. J Nutr Health Aging，2006，10(2):161-167.
[10]	TANAKA T, TAKAHASHI K, HIRANO H, et al. Oral frailty as a risk factor for physical frailty and mortality in community-dwelling elderly[J]. J Gerontol A Biol Sci Med Sci，2018，73(12):1661-1667. DOI：10.1093/gerona/glx225.
[11]	TAKEUCHI N, SAWADA N, EKUNI D, et al. Oral diadochokinesis is related to decline in swallowing function among community-dwelling Japanese elderly：a cross-sectional study[J]. Aging Clin Exp Res，2021，33(2):399-405. DOI：10.1007/s40520-020-01547-7.
[12]	SHIMAZAKI Y, NONOYAMA T, TSUSHITA K, et al. Oral hypofunction and its association with frailty in community-dwelling older people[J]. Geriatr Gerontol Int，2020，20(10):917-926. DOI：10.1111/ggi.14015.
[13]	WATANABE Y, OKADA K, KONDO M, et al. Oral health for achieving longevity[J]. Geriatr Gerontol Int，2020，20(6):526-538. DOI：10.1111/ggi.13921.
[14]	PARISIUS K G H, WARTEWIG E, SCHOONMADE L J, et al. Oral frailty dissected and conceptualized：a scoping review[J]. Arch Gerontol Geriatr，2022，100:104653. DOI：10.1016/j.archger.2022.104653.
[15]	IWASAKI M, WATANABE Y, MOTOKAWA K, et al. Oral frailty and gait performance in community-dwelling older adults：findings from the Takashimadaira study[J]. J Prosthodont Res，2021，65(4):467-473. DOI：10.2186/jpr.JPR_D_20_00129.
[16]	HILTUNEN K, SAARELA R K T, KAUTIAINEN H, et al. Relationship between Fried's frailty phenotype and oral frailty in long-term care residents[J]. Age Ageing，2021，50(6):2133-2139. DOI：10.1093/ageing/afab177.
[17]	CHOI J H, KANG J H, KOH S B, et al. Development of an Oral and Maxillofacial Frailty Index：a preliminary study[J]. J Oral Rehabil，2020，47(2):187-195. DOI：10.1111/joor.12890.
[18]	TANAKA T, HIRANO H, OHARA Y, et al. Oral Frailty Index-8 in the risk assessment of new-onset oral frailty and functional disability among community-dwelling older adults[J]. Arch Gerontol Geriatr，2021，94:104340. DOI：10.1016/j.archger.2021.104340.
[19]	NOMURA Y, ISHII Y, CHIBA Y, et al. Structure and validity of questionnaire for oral frail screening[J]. Healthcare （Basel），2021，9(1):45. DOI：10.3390/healthcare9010045.
[20]	BELAFSKY P C, MOUADEB D A, REES C J, et al. Validity and reliability of the eating assessment tool （EAT-10）[J]. Ann Otol Rhinol Laryngol，2008，117(12):919-924. DOI：10.1177/000348940811701210.
[21]	NISHIDA T, YAMABE K, IDE Y, et al. Utility of the eating assessment tool-10 （EAT-10） in evaluating self-reported dysphagia associated with oral frailty in Japanese community-dwelling older people[J]. J Nutr Health Aging，2020，24(1):3-8. DOI：10.1007/s12603-019-1256-0.
[22]	BUSH L A, HORENKAMP N, MORLEY J E, et al. D-E-N-T-A-L：a rapid self-administered screening instrument to promote referrals for further evaluation in older adults[J]. J Am Geriatr Soc，1996，44(8):979-981. DOI：10.1111/j.1532-5415.1996.tb01872.x.
[23]	王志燕，高欢玲，张红梅，等. Kihon老年衰弱筛查量表的汉化及信效度检验[J]. 护理学杂志，2021，36(3):10-13. DOI：10.3870/j.issn.1001-4152.2021.03.010.
[24]	KUGIMIYA Y, WATANABE Y, UEDA T, et al. Rate of oral frailty and oral hypofunction in rural community-dwelling older Japanese individuals[J]. Gerodontology，2020，37(4):342-352. DOI：10.1111/ger.12468.
[25]	KOMATSU R, NAGAI K, HASEGAWA Y, et al. Association between physical frailty subdomains and oral frailty in community-dwelling older adults[J]. Int J Environ Res Public Health，2021，18(6):2931. DOI：10.3390/ijerph18062931.
[26]	HOSHINO D, HIRANO H, EDAHIRO A, et al. Association between oral frailty and dietary variety among community-dwelling older persons：a cross-sectional study[J]. J Nutr Health Aging，2021，25(3):361-368. DOI：10.1007/s12603-020-1538-6.
[27]	SUZUKI F, OKAMOTO S, MIYAGI S, et al. Relationship between decreased mineral intake due to oral frailty and bone mineral density：findings from shika study[J]. Nutrients，2021，13(4):1193. DOI：10.3390/nu13041193.
[28]	NISHIDA T, YAMABE K, HONDA S. Dysphagia is associated with oral，physical，cognitive and psychological frailty in Japanese community-dwelling elderly persons[J]. Gerodontology，2020，37(2):185-190. DOI：10.1111/ger.12455.
[29]	IWASAKI M, MOTOKAWA K, WATANABE Y, et al. Association between oral frailty and nutritional status among community-dwelling older adults：the takashimadaira study[J]. J Nutr Health Aging，2020，24(9):1003-1010. DOI：10.1007/s12603-020-1433-1.
[30]	IWASAKI M, MOTOKAWA K, WATANABE Y, et al. A two-year longitudinal study of the association between oral frailty and deteriorating nutritional status among community-dwelling older adults[J]. Int J Environ Res Public Health，2020，18(1):E213. DOI：10.3390/ijerph18010213.
[31]	HASEGAWA Y, SAKURAMOTO-SADAKANE A, NAGAI K, et al. Does oral hypofunction promote social withdrawal in the older adults? A longitudinal survey of elderly subjects in rural Japan[J]. Int J Environ Res Public Health，2020，17(23):E8904. DOI：10.3390/ijerph17238904.
[32]	SHIROBE M, WATANABE Y, TANAKA T, et al. Effect of an oral frailty measures program on community-dwelling elderly people：a cluster-randomized controlled trial[J]. Gerontology，2021:1-10. DOI：10.1159/000516968.
[33]	MATSUO K, KITO N, OGAWA K, et al. Improvement of oral hypofunction by a comprehensive oral and physical exercise programme including textured lunch gatherings[J]. J Oral Rehabil，2021，48(4):411-421. DOI：10.1111/joor.13122.
[34]	NOMURA Y, ISHII Y, SUZUKI S, et al. Nutritional status and oral frailty：a community based study[J]. Nutrients，2020，12(9):E2886. DOI：10.3390/nu12092886.
[35]	DIBELLO V, LOZUPONE M, MANFREDINI D, et al. Oral frailty and neurodegeneration in Alzheimer's disease[J]. Neural Regen Res，2021，16(11):2149-2153. DOI：10.4103/1673-5374.310672.
[36]	HIRONAKA S, KUGIMIYA Y, WATANABE Y, et al. Association between oral，social，and physical frailty in community-dwelling older adults[J]. Arch Gerontol Geriatr，2020，89:104105. DOI：10.1016/j.archger.2020.104105.
[37]	BABA H, WATANABE Y, MIURA K, et al. Oral frailty and carriage of oral Candida in community-dwelling older adults （Check-up to discover Health with Energy for senior Residents in Iwamizawa；CHEER Iwamizawa）[J]. Gerodontology，2022，39(1):49-58. DOI：10.1111/ger.12621.
[38]	HIHARA T, GOTO T, ICHIKAWA T. Investigating eating behaviors and symptoms of oral frailty using questionnaires[J]. Dent J （Basel），2019，7(3):E66. DOI：10.3390/dj7030066.
[39]	NISHIMOTO M, TANAKA T, TAKAHASHI K, et al. Oral frailty is associated with food satisfaction in community-dwelling older adults[J]. Nihon Ronen Igakkai Zasshi，2020，57(3):273-281. DOI：10.3143/geriatrics.57.273.
[40]	HATANAKA Y, FURUYA J, SATO Y, et al. Associations between oral hypofunction tests，age，and sex[J]. Int J Environ Res Public Health，2021，18(19):10256. DOI：10.3390/ijerph181910256.
[41]	OHARA Y, MOTOKAWA K, WATANABE Y, et al. Association of eating alone with oral frailty among community-dwelling older adults in Japan[J]. Arch Gerontol Geriatr，2020，87:104014. DOI：10.1016/j.archger.2020.104014.

Recent Developments in Oral Frailty in the Elderly

老年人口腔衰弱的研究进展

RichHTML

PDF

Knowledge

Abstract

Cite this article

share this article

References 41

Related Articles 15

Recommended Articles

Metrics

Comments

[1]	TIAN Chen, LIU Jianing, TIAN Jinhui, GE Long. Living Systematic Reviews: Methods and Processes for Development [J]. Chinese General Practice, 2025, 28(30): 3853-3860.
[2]	WANG Tingting, TANG Yong, ZHANG Wenke, LI Zhigang. Research Progress on Exercise Intervention of Hyperuricemia [J]. Chinese General Practice, 2025, 28(30): 3841-3846.
[3]	LI Ling, LI Yaping, QIAN Shixing, NIE Jing, LU Chunhua, LI Xia. Research on Influencing Factors and Risk Prediction of Cognitive Function in Community-dwelling Middle-aged and Elderly People [J]. Chinese General Practice, 2025, 28(30): 3773-3778.
[4]	XU Jialan, YAN Hong, WEN Jun, ZHOU Zitong, WANG Siyu. Prevalence of Potentially Inappropriate Medication in Older Adults with Cancer: a Meta-analysis [J]. Chinese General Practice, 2025, 28(30): 3815-3822.
[5]	ZHOU Sheng, DENG Changsheng, ZOU Guanyang, SONG Jianping. Research Progress on the Pathogenesis of Complications of Malaria in Cardiovascular Diseases [J]. Chinese General Practice, 2025, 28(27): 3466-3472.
[6]	CHENG Yuxin, FANG Jiamin, LIANG Hao, WANG Zhiling, WEI Li, LIAO Huilian, XU Mingming, CHEN Yumei, LI Yanfen, DONG Lijuan, GUO Yingui. Preoperative Platelet-to-albumin Ratio in Elective Geriatric Surgery Patients and Its Correlation with Postoperative Incidental Frailty: a Multicenter Study [J]. Chinese General Practice, 2025, 28(27): 3359-3367.
[7]	HU Jieman, TAN Feixiang, YUAN Anxin, CHEN Shiyu, TANG Chulei, YIN Yueheng, BA Lei, XU Qin. Analysis of the Trajectory of Postoperative Frailty and Influencing Factors in Patients with Colorectal Cancer [J]. Chinese General Practice, 2025, 28(26): 3276-3282.
[8]	CHOU Xintong, PENG Hanyu, MA Hui, ZHANG Zhen, SU Xian, QIU Hongyan. Maternal Preferences in Contraceptive Decision-making: an Analysis of Influencing Factors [J]. Chinese General Practice, 2025, 28(26): 3294-3299.
[9]	WEI Jiaohua, PENG Huiru, PENG Jianye, TAN Wenting, HUANG Jine, FANG Li. Expression of the Serum MOTS-c and Its Correlation with Atrial Remodeling in Patients with Atrial Fibrillation [J]. Chinese General Practice, 2025, 28(26): 3271-3276.
[10]	HUANG Yulin, WANG Haoyun, LI Yanmei, XIAO Xueying. Symptom Clusters in Gastric Cancer Patients Receiving Chemotherapy: a Scoping Review [J]. Chinese General Practice, 2025, 28(26): 3338-3344.
[11]	YU Zizi, LIU Duli, LI Ximin, RUAN Chunyi, YIN Xiangyang, CAI Le. Analysis of the Prevalence and Self-management of Hypertension and Its Influencing Factors in Rural [J]. Chinese General Practice, 2025, 28(25): 3137-3143.
[12]	FAN Boyang, ZHANG Yu, SUN Wenning, ZHANG Huifang, WANG Yingjie, ZHANG Ao, ZHAO Yang, WANG Haipeng. Study of Behavioral Intention and Influencing Factors of Integrated Medical and Preventive Care Provided by Grassroots Doctors for Patients with Chronic Diseases [J]. Chinese General Practice, 2025, 28(25): 3144-3150.
[13]	YU Wenhua, LI Jianguo, DUAN Wenyan, GAO Xuyan, LI Xiaxia, ZHANG Zilong, ZHANG Li, MA Lina. Reliability and Validity of the Function Impairment Screening Tool among Community-dwelling Older Adults [J]. Chinese General Practice, 2025, 28(24): 3000-3004.
[14]	WANG Rupeng, NAN Jing, HU Yiran, YANG Shenghua, JIN Zening. Predictive Value of the Triglyceride-Glucose Body Mass Index for Slow Flow/No-reflow Phenomenon in Patients with Type 2 Diabetes Mellitus and Acute Myocardial Infarction Undergoing Emergency Percutaneous Coronary Intervention [J]. Chinese General Practice, 2025, 28(24): 2985-2992.
[15]	LI Jiaxin, LIU Zhonghui, XIE Shuo, FU Zhifang, SUN Dan, JIAO Hongmei. Trajectory in Biomarkers of Metabolic and Inflammatory States as Early Predictors of Chronic Critical Illness in Aging Patients [J]. Chinese General Practice, 2025, 28(24): 2993-2999.