Abstract: Background　Antenatal depression is one of the common stress reactions in pregnancy with a high incidence，which affects the health of women and newborns，and the family's quality of life.In extreme cases，self-injury and suicidal ideation and behavior may occur.The research on the depression and suicide ideation of pregnant women has important clinical value of preventing adverse perinatal events and improving perinatal health care.Objective　To explore the relationship between depression and suicidal ideation in pregnant women and its risk factors.Methods　A total of 448 pregnant women in Nanfang Hospital and Nanhai Hospital of Southern Medical University in Guangdong Province were investigated with the Patient Health Questionnaire（PHQ-9），Social Support Rating Scale（SSRS），Simple Coping Style Questionnaire（SCSQ），Eysenck Personality Questionnaire-Revised Short Scale for Chinese（EPQ-RSC） and Basic Data Questionnaire from January to April in 2018.Spearman rank correlation was used to analyze the relationship between depression and suicidal ideation.Binary Logistic regression was used to analyze the relationship among antenatal depression，suicidal ideation and psychosocial factors.Results　The incidence of depression and suicide ideation in pregnant women were 47.8% and 6.9% respectively and there was a positive correlation between them（rs=0.250，P<0.001）．The binary Logistic regression analysis showed that unemployment or being housewives，the family income is less than 3 000 yuan，and high score of psychophysical dimension were risk factors for the depression in pregnant women（OR=1.568，1.860，1.539，P<0.05）．While the risk factors of suicidal ideation in pregnant women were living in rural area，low level of social support，high score of internal and external dimension and introverted personality（OR=2.703，12.148，5.374，15.550，P<0.05）．Conclusion　Antenatal depression is positively correlated with suicidal ideation.We should pay attention to screening for serious psychological problems during pregnancy period of a woman，and focus on pregnant women who are unemployed or housewives（without stable occupations），live in rural areas，and have low monthly household income，low level of social support，negative coping styles，high scores in internal and external dimension and psychophysical dimension.

Key words: Depressive disorder, Pregnancy, Suicidal ideation, Risk factors

摘要： 背景　妊娠期抑郁是常见的妊娠应激性反应之一，发生率较高，影响本人和新生儿健康以及家庭的生活质量，严重时会出现自伤、自杀意念和行为。开展妊娠期女性抑郁、自杀意念的相关研究，对于预防围生期不良事件、促进围生期保健具有重要的临床价值。目的　了解妊娠期女性抑郁与自杀意念的关系及其危险因素。方法　2018年1—4月采用患者健康问卷（PHQ-9）、社会支持评定量表（SSRS）、简易应对方式问卷（SCSQ）、艾森克人格问卷简式量表中国版（EPQ-RSC）和基本资料调查表对广东省两家医院（南方医科大学南方医院和南方医科大学南海医院）共448例妊娠期女性进行调查，妊娠期抑郁和自杀意念的相关性采用Spearman秩相关分析，使用二元Logistic回归分析探讨妊娠期抑郁、自杀意念与心理社会因素之间的关系。结果　妊娠期女性抑郁率、自杀意念发生率分别为47.8%和6.9%，妊娠期抑郁和自杀意念呈正相关（rs=0.250，P<0.001）。二元Logistic回归分析表明：失业或家庭主妇、家庭月收入3 000元以下、精神质维度得分高是妊娠期女性抑郁的危险因素（OR=1.568、1.860、1.539，P<0.05），居住地为农村、社会支持一般、应对方式消极、内外向维度得分高是妊娠期女性自杀意念的危险因素（OR=2.703、12.148、5.374、15.550，P<0.05）。结论　妊娠期抑郁与自杀意念呈正相关，应该重视妊娠期严重心理问题的筛查，要重点关注失业或家庭主妇（无稳定职业者）、居住地为农村、家庭月收入低、社会支持水平一般、应对方式消极、内外向维度得分高及精神质维度得分高的孕妇。

关键词: 抑郁症, 妊娠, 自杀意念, 危险因素