The Role of Exercise in the Management of Metabolic-associated Fatty Liver Disease: Interpretation of the International Expert Consensus of ACSM and ESSA

doi:10.12114/j.issn.1007-9572.2025.0359

Chinese General Practice ›› 2026, Vol. 29 ›› Issue (23): 3253-3260.DOI: 10.12114/j.issn.1007-9572.2025.0359

• Monographic Research·MAFLD • Previous Articles Next Articles

The Role of Exercise in the Management of Metabolic-associated Fatty Liver Disease: Interpretation of the International Expert Consensus of ACSM and ESSA

1. School of Physical Education, Henan University, Kaifeng 475000, China
2. Department of Endocrinology, Henan Province Hospital of TCM/The Second Affiliated Hospital of Henan University of Chinese Medicine, Zhengzhou 450003, China
3. Department of Rehabilitation, Henan Provincial People's Hospital/Zhengzhou University People's Hospital, Zhengzhou 450003, China
4. Editorial Department, Henan Provincial People's Hospital/Zhengzhou University People's Hospital, Zhengzhou 450003, China
5. School of Basic Medical Sciences, Henan University, Kaifeng 475000, China

Received:2025-09-03 Revised:2025-12-10 Published:2026-08-15 Online:2026-07-03
Contact: CHENG Jingwei
About author:
XU Kun and CHENG Jingwei are co-first authors

运动在代谢相关脂肪性肝病管理中的作用：美国运动医学会和澳大利亚运动与体育科学学会国际专家共识解读

1．475000　河南省开封市，河南大学体育学院
2．450003　河南省郑州市，河南省中医院　河南中医药大学第二附属医院内分泌科
3．450003　河南省郑州市，河南省人民医院　郑州大学人民医院康复科
4．450003　河南省郑州市，河南省人民医院　郑州大学人民医院编辑部
5．475000　河南省开封市，河南大学基础医学院

通讯作者: 程经纬
作者简介:
许坤和程经纬为共同第一作者
作者贡献：
许坤负责研究构思与设计、论文起草与撰写；王聪帅、王银浩负责论文研究资料的收集与整理；胡俊鹏、李弯月负责论文知识性审查与学术指导；柳杨青负责论文修订；席艳负责研究过程的监督管理；程经纬负责论文的质量控制及审校、对论文整体负责。
基金资助:
河南省重点研发专项(241112310500)

Abstract

Abstract:

Exercise is the cornerstone of metabolic-associated fatty liver disease(MAFLD) management and a core approach to reversing hepatic steatosis and reducing cardiovascular risk. Currently, there are no effective therapeutic drugs approved by regulatory authorities for MAFLD, thus patients with MAFLD need more precise exercise prescription guidance. However, there are relatively few exercise guidelines specifically for MAFLD patients at present. With the continuous exploration of this field by experts and scholars, in the past two years, American College of Sports Medicine (ACSM) and Exercise and Sport Science Australia (ESSA) respectively released expert consensuses on exercise guidance recommendations for patients with MAFLD: American College of Sports Medicine (ACSM) International Multidisciplinary Roundtable Report on Physical Activity and Nonalcoholic Fatty Liver Disease and Exercise in the Management of Metabolic-associated Fatty Liver Disease (MAFLD) in Adults: a Position Statement from Exercise and Sport Science Australia. These two expert consensuses comprehensively put forward guiding opinions from the perspectives of the mechanism by which exercise improves hepatic steatosis, the impact of different types of exercise on MAFLD, the benefits of exercise for MAFLD patients, and the formulation of exercise prescriptions. This article interpreted the main contents of the expert consensus, aiming to provide more scientific exercise guidance for domestic MAFLD patients.

Key words: Metabolic-associated fatty liver disease, Physical activity, Exercise prescriptions, American College of Sports Medicine, Exercise and Sport Science Australia, Guideline interpretation

摘要：

运动是代谢相关脂肪性肝病（MAFLD）管理的基石，也是逆转肝脂肪变性、降低心血管疾病风险的核心手段。目前尚无监管机构批准的有效治疗药物，因此MAFLD患者需要更精准的运动处方指导。然而，目前针对MAFLD患者的运动指南相对较少。近两年美国运动医学会（ACSM）和澳大利亚运动与体育科学学会（ESSA）分别发布了关于MAFLD患者运动指导建议的专家共识——《ACSM国际多学科圆桌会议关于体育活动和非酒精性脂肪肝的报告》和《运动在成年人代谢相关脂肪性肝病（MAFLD）管理中的作用：ESSA的立场声明》，从运动改善肝脂肪变性的机制、不同运动类型对MAFLD的影响、运动对MAFLD患者的益处、运动处方制定等角度全面提出了指导意见。本文对专家共识的主要内容进行解读，旨在为国内MAFLD患者提供更科学的运动指导。

CLC Number:

R 575.5

XU Kun,CHENG Jingwei,WANG Congshuai, et al. The Role of Exercise in the Management of Metabolic-associated Fatty Liver Disease: Interpretation of the International Expert Consensus of ACSM and ESSA[J]. Chinese General Practice, 2026, 29(23): 3253-3260. DOI: 10.12114/j.issn.1007-9572.2025.0359.
许坤,程经纬,王聪帅等. 运动在代谢相关脂肪性肝病管理中的作用：美国运动医学会和澳大利亚运动与体育科学学会国际专家共识解读[J]. 中国全科医学, 2026, 29(23): 3253-3260. DOI: 10.12114/j.issn.1007-9572.2025.0359.

Figures/Tables 3

References 43

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The Role of Exercise in the Management of Metabolic-associated Fatty Liver Disease: Interpretation of the International Expert Consensus of ACSM and ESSA

运动在代谢相关脂肪性肝病管理中的作用：美国运动医学会和澳大利亚运动与体育科学学会国际专家共识解读

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