Abstract: Exercise is the cornerstone of metabolic-associated fatty liver disease(MAFLD) management and a core approach to reversing hepatic steatosis and reducing cardiovascular risk. Currently, there are no effective therapeutic drugs approved by regulatory authorities for MAFLD, thus patients with MAFLD need more precise exercise prescription guidance. However, there are relatively few exercise guidelines specifically for MAFLD patients at present. With the continuous exploration of this field by experts and scholars, in the past two years, American College of Sports Medicine (ACSM) and Exercise and Sport Science Australia (ESSA) have respectively released expert consensuses on exercise guidance recommendations for patients with MAFLD: American College of Sports Medicine (ACSM) International Multidisciplinary Roundtable report on physical activity and nonalcoholic fatty liver disease and Exercise in the management of metabolic-associated fatty liver disease (MAFLD) in adults: a position statement from Exercise and Sport Science Australia. These two expert consensuses comprehensively put forward guiding opinions from the perspectives of the mechanism by which exercise improves hepatic steatosis, the impact of different types of exercise on MAFLD, the benefits of exercise for MAFLD patients, and the formulation of exercise prescriptions. This article interprets the main contents of the expert consensus, aiming to provide more scientific exercise guidance for domestic MAFLD patients.

Key words: Metabolic-associated fatty liver disease, Physical activity, Exercise prescriptions, American College of Sports Medicine, Exercise and Sport Science Australia, Guideline interpretation

摘要： 运动是代谢相关脂肪性肝病（MAFLD）管理的基石，也是逆转肝脂肪变性、降低心血管疾病风险的核心手段。目前尚无监管机构批准的有效治疗药物，因此 MAFLD 患者需要更精准的运动处方指导。然而，目前针对MAFLD 患者的运动指南相对较少。随着专家学者对该领域的不断探索，近两年美国运动医学会（ACSM）和澳大利亚运动与体育科学学会（ESSA）分别发布了关于 MAFLD 患者运动指导建议的专家共识——《ACSM 国际多学科圆桌会议关于体育活动和非酒精性脂肪肝的报告》和《运动在成人代谢相关脂肪性肝病（MAFLD）管理中的作用：ESSA 的立场声明》，从运动改善肝脂肪变性的机制、不同运动类型对 MAFLD 的影响、运动对 MAFLD 患者的益处、运动处方制定等角度全面提出了指导意见。本文对专家共识的主要内容进行解读，旨在为国内 MAFLD 患者提供更科学的运动指导。

关键词: 代谢相关脂肪性肝病, 身体活动, 运动处方, 美国运动医学会, 澳大利亚运动与体育科学学会, 指南解读