Chinese General Practice ›› 2025, Vol. 28 ›› Issue (32): 4031-4037.DOI: 10.12114/j.issn.1007-9572.2024.0620

Special Issue: 内分泌代谢性疾病最新文章合辑

• Original Research·Multimorbidity Section • Previous Articles     Next Articles

Comparison of Prevalence and Comorbidity of Hypertension, Diabetes and Dyslipidemia in Xinjiang Residents

  

  1. 1. Department of Medical Laboratory, Hospital of Xinjiang Production and Construction Corps/Second Affiliated Hospital of Shihezi University School of Medicine, Urumqi 830002, China
    2. Corps Clinical Medical Research Center for Medical Laboratory, Urumqi 830002, China
    3. Department of Medical Laboratory, General Hospital of the Third Division of Xinjiang Production and Construction Corps, Tumushuke 843900, China
  • Received:2025-01-06 Revised:2025-05-23 Published:2025-11-15 Online:2025-09-23
  • Contact: ZHANG Xin

新疆地区居民高血压、糖尿病、血脂异常患病及共病情况研究

  

  1. 1.830002 新疆维吾尔自治区乌鲁木齐市,新疆生产建设兵团医院 石河子大学医学院第二附属医院检验科
    2.830002 新疆维吾尔自治区乌鲁木齐市,兵团医学检验临床医学研究中心
    3.843900 新疆维吾尔自治区图木舒克市,新疆生产建设兵团第三师医院检验科
  • 通讯作者: 张新
  • 作者简介:

    作者贡献:

    刘春燕负责本研究的构思与设计、研究的实施和论文撰写;邓朝晖、宋颖博、杨芳进行数据收集与整理,统计学处理,图表的绘制与展示;史茜、李永鑫进行论文修订;张新负责文章的质量控制与审查,对文章整体负责,监督管理。

  • 基金资助:
    国家临床重点专科建设项目(兵财社〔2023〕16号); 兵团重点领域科技攻关计划项目(2020AB021); 师市重点领域科技攻关计划项目(KY2021GG04)

Abstract:

Background

Hypertension, diabetes, and dyslipidemia-commonly referred to as the "three highs" —are significant risk factors for cardiovascular and cerebrovascular diseases. Co-managing these conditions is crucial for reducing the morbidity and mortality associated with cardiovascular and cerebrovascular diseases; however, there is a notable lack of relevant research on the comorbidities of the "three highs" in Xinjiang.

Objective

To analyze the comparison of prevalence and comorbidity of hypertension, diabetes and dyslipidemia in Xinjiang residents, thereby providing data support for the co-management of the "three highs" within the local population.

Methods

Data were collected from the baseline of the Chronic Disease Prevention and Control Project of the Xinjiang Production and Construction Corps. A total of 5 673 residents aged 18 years and older participated in a questionnaire survey, physical examination, and laboratory examination conducted in 2022. In this study, the survey data of 4 990 eligible residents (87.96%) were included. The prevalence of the "three highs" (hypertension, hyperglycemia, and hyperlipidemia) and the comorbidity rate were analyzed. Multivariate Logistic regression analysis was employed to identify the risk factors associated with comorbidity of the "three highs" .

Results

A total of 4 990 cases were included in the study, comprising 2 043 (40.94%) Han individuals, 2 666 (53.43%) Uygur individuals, and 281 (5.63%) from other ethnic groups. The standardized prevalence rates for hypertension, diabetes, and dyslipidemia were 32.66%, 14.03%, and 39.20%, respectively. The standardized prevalence of comorbidities was as follows: hypertension with diabetes (8.83%) , hypertension with dyslipidemia (15.31%) , and diabetes with dyslipidemia (8.05%) . The standardized comorbidity rate of the "three highs" was 5.36%. The rates of comorbidity for two and three diseases increased with age and body mass index (BMI) while decreasing with higher levels of education (P<0.05) . The dyslipidemia of the residents primarily characterized by elevated triglyceride levels (TG) (16.47%, 822/4 990) and low high-density lipoprotein cholesterol (HDL-C) levels (15.29%, 763/4 990) , with the prevalence of high total cholesterol (TC) and low-density lipoprotein cholesterol (LDL-C) being significantly lower in men than in women (P<0.05) . Results from multivariate Logistic regression analysis indicated that age, BMI grade, and educational level were influencing factors for the comorbidity of "three highs" (P<0.05) .

Conclusion

The prevention and control of comorbidities associated with the "three highs" in Xinjiang remains challenging. Advanced age, overweight/obesity, and low educational attainment were risk factors for the comorbidity of the "three highs" . The joint management of the "three highs" and the comprehensive management of risk factors are crucial for the prevention and control of chronic diseases in the region.

Key words: Hypertension, Diabetes mellitus, Dyslipidemias, Multiple chronic conditions, Root cause analysis

摘要:

背景

高血压、糖尿病、血脂异常(简称"三高")是心脑血管疾病的重要危险因素,"三高"共管对降低心脑血管疾病的发病率和死亡率具有重要意义,但目前缺乏关于新疆地区"三高"共病情况的研究。

目的

探讨新疆地区居民高血压、糖尿病及血脂异常的患病和共病情况,为新疆地区人群的"三高"共管提供数据支撑。

方法

数据来源于新疆生产建设兵团慢性病防控项目的基线调查,该调查于2022年开展,对新疆地区5 673名≥18岁的常住居民进行问卷调查、体格检查及实验室检查。纳入研究相关数据完整的4 990名(87.96%)居民的调查资料,分析其高血压、糖尿病、血脂异常的患病率及共病率,并采用多因素Logistic回归模型分析"三高"共病的影响因素。

结果

4 990名居民中,汉族2 043名(40.94%)、维吾尔族2 666名(53.43%)、其他民族281名(5.63%)。高血压、糖尿病、血脂异常的标化患病率分别为32.66%、14.03%、39.20%,高血压合并糖尿病、高血压合并血脂异常、糖尿病合并血脂异常的标化共病率分别为8.83%、15.31%、8.05%,"三高"标化共病率为5.36%。2种及3种疾病共病率均随年龄和BMI的升高而呈现上升趋势(P<0.05),随文化程度增加而呈现下降趋势(P<0.05)。居民的血脂异常表现形式以高三酰甘油血症(16.47%,822/4 990)和低高密度脂蛋白胆固醇血症(15.29%,763/4 990)为主,男性高总胆固醇血症、高低密度脂蛋白胆固醇血症患病率低于女性(P<0.05)。多因素Logistic回归分析结果显示,年龄、BMI分级、文化程度是新疆地区居民"三高"共病的影响因素(P<0.05)。

结论

新疆地区居民"三高"共病的防控形势仍较严峻,高龄、超重/肥胖、文化程度低是"三高"共病的危险因素,"三高"共管和危险因素综合管理是该地区人群慢性病防控的关键。

关键词: 高血压, 糖尿病, 血脂异常, 慢性病共病, 影响因素分析