More and more studies have proved that heart failure with supra-normal ejection fraction (HFsnEF) is a new heart failure phenotype with different characteristics, but its study is still in the exploratory stage at home and abroad. The critical value of supernormal ejection fraction (snLVEF) is still controversial, but most studies define it as left ventricular ejection fraction>65%; the proportion of elderly and female patients with HFsnEF is higher, with lower natriuretic peptide values and smaller left ventricles, and valvular disease, arrhythmia, and hypertensive heart disease are the main causes of heart failure; and the relationship between HFsnEF and mortality has a gender-dependent nature, possibly due to the prevalence of coronary microvascular disorders in elderly women, coupled with small heart size and high sympathetic excitability, making them more likely to suffer cardiovascular events; the current diagnosis and treatment of HFsnEF still follows the HFpEF approach. By combing the literature, this paper systematically discusses the research progress of HFsnEF, with a view to providing a reference for the in-depth study of HFsnEF.

目前越来越多的研究证明射血分数超常的心力衰竭（HFsnEF）是一种新的心力衰竭表型，具有不同的特点，目前国内外对其研究仍处于探索阶段。目前对于超常射血分数（snLVEF）的临界值存有争议，但多数研究将其定义为左心室射血分数>65%；HFsnEF患者老年人、女性的比例更高，脑钠肽值更低，左心室更小，瓣膜疾病、心律失常和高血压性心脏病是主要的心力衰竭病因；HFsnEF和死亡率之间的关系具有性别依赖性，可能由于老年女性好发冠状动脉微血管障碍，加之心脏体积小、交感神经兴奋性高，使其更有可能发生心血管事件。目前对于HFsnEF的诊断和治疗仍沿用射血分数保留的心力衰竭的方法。本文通过梳理文献，系统地探讨了HFsnEF的研究进展，以期为HFsnEF的深入研究提供借鉴。