In China, chronic diseases have become a major public health problem threatening residents' health. Highlighted in the national policies, primary care settings should act as the "main battlefield" for fighting chronic diseases.

To understand the topics, hot spots and development trends in chronic disease management in primary care of China, providing evidence for further research.

In September 2021, relevant literature of chronic disease management in primary care in China were searched in databases of SinoMed, CNKI, Wanfang Data, and CQVIP from inception to September 13, 2021. Endnote X9 was used to conduct statistical analysis of the annual number of publications, distribution of journals, and distribution of institutions.VOSviewer 1.6.14 was adopted for high-frequency keywords analysis, network analysis of keyword co-occurrence, timeline view of keyword co-occurrence network, and visualizing the knowledge map.

In total, 4 060 articles published since 1977 (as of September 13, 2021) were included. The annual number of published articles demonstrated an upward trend in general. The journal with the highest number of articles was Chinese General Practice〔329 articles (8.10%) 〕. Fudan University was the most prolific institution〔1.75% (71/4 060) 〕. The top 10 high-frequency keywords were chronic diseases〔8.75% (895/10 224) 〕, community〔7.49% (766/10 224) 〕, elderly people〔4.90% (501/10 224) 〕, diabetes〔4.62% (472/10 224) 〕, hypertension〔4.28% (438/10 224) 〕, chronic obstructive pulmonary disease〔4.22% (431/10 224) 〕, prevalence〔4.04% (413/10 224) 〕, influencing factors〔3.29% (336/10 224) 〕, risk factors〔2.60% (266/10 224) 〕 and quality of life〔1.95% (199/10 224) 〕. Four major hot topics were identified by network analysis of keyword co-occurrence: chronic disease management of the elderly in the community, epidemiology of risk factors for chronic diseases, management and community-based comprehensive prevention and treatment regarding chronic diseases (such as hypertension and diabetes) , community-based nursing and rehabilitation of chronic diseases (mainly for chronic obstructive pulmonary disease) . Hierarchical diagnosis and treatment and contracted family doctor services, informationization and Internet-based services, mental or sleep health, multimorbidity, general practitioner and pharmaceutical care were recently emgerged research themes identified by timeline view of keyword co-occurrence network.

The number of studies about of chronic disease management in primary care in China demonstrated an overall upward trend, with management of hypertension, diabetes, and chronic obstructive pulmonary disease in primary care as the research hotspots. Studies on hierarchical diagnosis and treatment and contracted family doctor service, informationization and Internet-based services, mental or sleep health, multimorbidity, and general practitioner and pharmaceutical care are in the ascendant.

慢性病已成为危害我国居民健康的重大公共卫生问题，国家政策强调要发挥基层在慢性病管理中的"主战场"作用。

了解我国基层慢性病管理领域研究主题、热点和发展趋势，旨在为后续研究提供参考。

于2021年9月，通过检索万方数据知识服务平台、中国知网、中国生物医学文献数据库、维普中文科技期刊全文数据库，获取关于基层慢性病管理的文献，检索时限均为建库至2021-09-13。应用Endnote X9软件，从年度发文数量、期刊分布、发文机构分布等方面进行统计分析；运用VOSviewer 1.6.14软件进行高频关键词分析、关键词共现聚类分析、关键词共现时间线分析，并对知识图谱进行可视化。

共纳入自1977年以来发表的研究型文献4 060篇，发文量整体上呈现上升趋势。发文量最多的期刊是《中国全科医学》，共发文329篇（8.10%）。复旦大学是发表基层慢性病管理相关文献数量最多的机构〔1.75%（71/4 060）〕。高频关键词分析结果显示，出现频次排在前10位的关键词依次为慢性病〔8.75%（895/10 224）〕、社区〔7.49%（766/10 224）〕、老年人〔4.90%（501/10 224）〕、糖尿病〔4.62%（472/10 224）〕、高血压〔4.28%（438/10 224）〕、慢性阻塞性肺疾病〔4.22%（431/10 224）〕、患病率〔4.04%（413/10 224）〕、影响因素〔3.29%（336/10 224）〕、危险因素〔2.60%（266/10 224）〕和生活质量〔1.95%（199/10 224）〕。关键词共现聚类分析结果显示，热点研究主题主要集中在社区老年人慢性病管理、慢性病危险因素的流行病学、高血压和糖尿病等慢性病的管理与社区综合防治，以及以慢性阻塞性肺疾病为主的慢性病社区护理与康复4个方面。关键词共现时间线分析结果显示，分级诊疗与家庭医生签约服务、信息化与"互联网+"、心理/睡眠健康、共病、全科医生与药学服务是近年来新兴的研究主题。

我国基层慢性病管理领域研究总体呈现上升趋势，高血压、糖尿病、慢性阻塞性肺疾病的基层管理是研究者关注的热点话题，分级诊疗与家庭医生签约服务、信息化与"互联网+"、心理/睡眠健康、共病、全科医生与药学服务相关研究方兴未艾。