Abstract: Background　Elderly people are at high risk of hypercholesterolemia.Marginally elevated serum cholesterol is a transitional stage from normal cholesterol level to hypercholesterolemia.Active interventions can effectively reduce the incidence of cardiovascular and cerebrovascular diseases in elderly people with marginally elevated serum cholesterol.Objective　To investigate the clinical effect of acupoint acupressure combined with exercise on the marginally elevated serum cholesterol in the elderly.Methods　We recruited 200 elderly health checkup examinees with marginally elevated serum cholesterol from Xuhang Community Health Center from May 2015 to May 2016.By use of the random number table，they were divided into 4 equal groups，the control group，exercise group，acupoint acupressure group，and acupoint acupressure with exercise group，receiving the conventional community-based health management，conventional community-based health management with wuzang yangsheng gymnastics，conventional community-based health management with acupoint acupressure，conventional community-based health management with acupoint acupressure and wuzang yangsheng gymnastics，respectively.The interventions for all groups lasted for 12 months.Treatment compliance and control rate of marginally elevated serum cholesterol were recorded during follow-ups at the end of the 6-month and 12-month interventions，and were compared between the groups.Results　At the end of the 6-month and 12-month interventions，exercise group，acupoint acupressure group，and acupoint acupressure with exercise group showed no significant difference in treatment compliance（P>0.05）．The control rate of marginally elevated serum cholesterol differed significantly across all 4 groups（P<0.05）．More specifically，compared with the control group，other 3 groups showed a higher control rate of marginally elevated serum cholesterol（P<0.05）；acupoint acupressure with exercise group demonstrated a higher control rate of marginally elevated serum cholesterol compared with exercise group and acupoint acupressure group（P<0.05）．Conclusion　Both acupoint acupressure and exercise can effectively reduce the level of serum total cholesterol and lower-density lipoprotein in the elderly，and the intervention effect is even better if the two are used combinedly.The combined intervention is recommended for clinical application and promotion.

Key words: Dyslipidemias, Cholesterol, Acupressure, Exercise therapy, Treatment outcome, Aged

摘要： 背景　老年人是高胆固醇血症的高发人群，血清胆固醇边缘性升高是发展至高胆固醇血症的过渡阶段，对血清胆固醇边缘性升高老年人进行积极干预可有效降低其心脑血管疾病发生率。目的　探讨体穴按压联合运动干预对老年人血清胆固醇边缘性升高的干预效果。方法　选取2015年5月—2016年5月在徐行镇社区卫生服务中心接受体检的血清胆固醇边缘性升高老年人200例，采用随机数字表法将其分为4组，每组50例。对照组仅接受社区常规管理，运动组在常规管理基础上进行五脏养生操运动，穴位组在常规管理基础上进行穴位按压，联合组在常规管理基础上进行穴位按压联合五脏养生操运动，4组均持续干预12个月。比较4组随访6个月后和12个月后的干预依从性、血清胆固醇边缘性升高控制率。结果　随访6个月后和12个月后，运动组、穴位组、联合组的干预依从性无差异（P>0.05）。随访6个月后和12个月后，4组血清胆固醇边缘性升高有效控制率存在差异（P<0.05）；其中运动组、穴位组、联合组的控制率高于对照组，联合组的控制率高于运动组、穴位组（P<0.05）。结论　穴位按压、运动干预均能有效降低老年人的血清总胆固醇和低密度脂蛋白胆固醇水平，二者联合干预效果更佳，建议在临床上推广应用。

关键词: 血脂异常, 胆固醇, 穴位按压, 运动疗法, 治疗效果, 老年人