Chinese General Practice ›› 2024, Vol. 27 ›› Issue (17): 2077-2082.DOI: 10.12114/j.issn.1007-9572.2023.0842
Special Issue: 脑健康最新研究合集
• Original Research • Previous Articles Next Articles
Received:
2023-12-02
Revised:
2024-02-19
Published:
2024-06-15
Online:
2024-03-22
Contact:
ZHU Ning
通讯作者:
朱宁
作者简介:
基金资助:
Add to citation manager EndNote|Ris|BibTeX
URL: https://www.chinagp.net/EN/10.12114/j.issn.1007-9572.2023.0842
组别 | 例数 | 年龄(岁) | 性别[例(%)] | BMI (kg/m2) | 颈围(cm) | 吸烟[例(%)] | 饮酒[例(%)] | |||
---|---|---|---|---|---|---|---|---|---|---|
男 | 女 | 是 | 否 | 是 | 否 | |||||
对照组 | 34 | 55.3±12.8 | 24(70.6) | 10(29.4) | 25.6±3.6 | 41.7±3.5 | 23(67.6) | 11(32.4) | 22(64.7) | 12(35.3) |
试验组 | 35 | 56.4±11.1 | 25(71.4) | 10(28.6) | 25.2±2.9 | 43.5±4.9 | 22(62.9) | 13(37.1) | 20(57.1) | 15(42.9) |
检验统计量值 | 0.394a | 0.006 | -0.513a | 1.807a | 0.174 | 0.414 | ||||
P值 | 0.695 | 0.939 | 0.610 | 0.075 | 0.676 | 0.520 | ||||
组别 | 受教育年限[M(P25,P75),年] | 基础疾病[例(%)] | AHI[例(%)] | 脑卒中类型[例(%)] | ||||||
高血压 | 糖尿病 | 高脂血症 | 5~15次/h | >15次/h | 出血 | 梗死 | ||||
对照组 | 11.50(9.75,14.00) | 7(20.6) | 6(17.6) | 8(23.5) | 10(29.4) | 24(70.6) | 6(17.6) | 28(82.4) | ||
试验组 | 12.00(10.00,14.00) | 8(22.9) | 6(17.1) | 6(17.1) | 10(28.6) | 25(71.4) | 6(17.1) | 29(82.9) | ||
检验统计量值 | -0.291b | 0.014 | 0.116 | 0.126 | 0.006 | 0.003 | ||||
P值 | 0.771 | 0.906 | 0.733 | 0.722 | 0.939 | 0.956 | ||||
组别 | 病程[M(P25,P75),d] | 病灶部位[例(%)] | NIHSS评分[M(P25,P75),分] | |||||||
小脑 | 脑干 | 皮质 | 下皮质 | 多部位 | ||||||
对照组 | 121.50(85.25,179.25) | 7(20.6) | 5(14.7) | 9(26.5) | 9(26.5) | 4(11.7) | 5.00(3.00,7.25) | |||
试验组 | 112.00(79.00,172.00) | 5(14.3) | 6(17.1) | 10(28.6) | 6(17.1) | 8(22.9) | 5.00(3.00,7.00) | |||
检验统计量值 | -0.240b | 2.396 | -0.405b | |||||||
P值 | 0.810 | 0.663 | 0.686 |
Table 1 Comparison of general data between the two groups
组别 | 例数 | 年龄(岁) | 性别[例(%)] | BMI (kg/m2) | 颈围(cm) | 吸烟[例(%)] | 饮酒[例(%)] | |||
---|---|---|---|---|---|---|---|---|---|---|
男 | 女 | 是 | 否 | 是 | 否 | |||||
对照组 | 34 | 55.3±12.8 | 24(70.6) | 10(29.4) | 25.6±3.6 | 41.7±3.5 | 23(67.6) | 11(32.4) | 22(64.7) | 12(35.3) |
试验组 | 35 | 56.4±11.1 | 25(71.4) | 10(28.6) | 25.2±2.9 | 43.5±4.9 | 22(62.9) | 13(37.1) | 20(57.1) | 15(42.9) |
检验统计量值 | 0.394a | 0.006 | -0.513a | 1.807a | 0.174 | 0.414 | ||||
P值 | 0.695 | 0.939 | 0.610 | 0.075 | 0.676 | 0.520 | ||||
组别 | 受教育年限[M(P25,P75),年] | 基础疾病[例(%)] | AHI[例(%)] | 脑卒中类型[例(%)] | ||||||
高血压 | 糖尿病 | 高脂血症 | 5~15次/h | >15次/h | 出血 | 梗死 | ||||
对照组 | 11.50(9.75,14.00) | 7(20.6) | 6(17.6) | 8(23.5) | 10(29.4) | 24(70.6) | 6(17.6) | 28(82.4) | ||
试验组 | 12.00(10.00,14.00) | 8(22.9) | 6(17.1) | 6(17.1) | 10(28.6) | 25(71.4) | 6(17.1) | 29(82.9) | ||
检验统计量值 | -0.291b | 0.014 | 0.116 | 0.126 | 0.006 | 0.003 | ||||
P值 | 0.771 | 0.906 | 0.733 | 0.722 | 0.939 | 0.956 | ||||
组别 | 病程[M(P25,P75),d] | 病灶部位[例(%)] | NIHSS评分[M(P25,P75),分] | |||||||
小脑 | 脑干 | 皮质 | 下皮质 | 多部位 | ||||||
对照组 | 121.50(85.25,179.25) | 7(20.6) | 5(14.7) | 9(26.5) | 9(26.5) | 4(11.7) | 5.00(3.00,7.25) | |||
试验组 | 112.00(79.00,172.00) | 5(14.3) | 6(17.1) | 10(28.6) | 6(17.1) | 8(22.9) | 5.00(3.00,7.00) | |||
检验统计量值 | -0.240b | 2.396 | -0.405b | |||||||
P值 | 0.810 | 0.663 | 0.686 |
组别 | 例数 | AHI(次/h) | SpO2(%) | |||||||||
---|---|---|---|---|---|---|---|---|---|---|---|---|
干预前 | 干预6周后 | t配对值 | P值 | 干预前 | 干预6周后 | t配对值 | P值 | |||||
对照组 | 34 | 30.25±18.65 | 18.27±10.36 | 7.507 | <0.001 | 90.82±2.82 | 94.35±1.95 | -12.294 | <0.001 | |||
试验组 | 35 | 31.06±20.22 | 15.85±9.97 | 7.391 | <0.001 | 91.49±3.08 | 96.34±1.51 | -12.994 | <0.001 | |||
t值 | -0.617 | -0.984 | 0.931 | 4.740 | ||||||||
P值 | 0.539 | 0.329 | 0.355 | <0.001 | ||||||||
组别 | LSaO2(%) | ODI(次/h) | ||||||||||
干预前 | 干预6周后 | t配对值 | P值 | 干预前 | 干预6周后 | t配对值 | P值 | |||||
对照组 | 77.76±8.58 | 88.03±4.74 | -11.916 | <0.001 | 30.74±18.91 | 20.12±12.33 | 8.073 | <0.001 | ||||
试验组 | 78.89±8.24 | 90.69±3.21 | -12.377 | <0.001 | 30.96±18.84 | 14.00±8.53 | 8.488 | <0.001 | ||||
t值 | 0.554 | 2.734 | 0.048 | -2.402 | ||||||||
P值 | 0.582 | 0.008 | 0.962 | 0.019 | ||||||||
组别 | 深睡眠比例(N3期睡眠占总睡眠时间比例)(%) | 觉醒指数(次/h) | ESS评分(分) | |||||||||
干预前 | 干预6周后 | t配对值 | P值 | 干预前 | 干预6周后 | t配对值 | P值 | 干预前 | 干预6周后 | t配对值 | P值 | |
对照组 | 16.08±8.50 | 24.72±5.50 | -13.505 | <0.001 | 20.24±7.10 | 10.38±3.49 | 8.895 | <0.001 | 13.44±4.08 | 8.68±2.28 | 10.807 | <0.001 |
试验组 | 14.54±7.50 | 27.47±4.71 | -18.041 | <0.001 | 16.60±9.81 | 5.99±3.88 | 7.410 | <0.001 | 12.80±4.78 | 7.26±2.93 | 12.756 | <0.001 |
t值 | -0.796 | 2.237 | -1.764 | -4.933 | -0.600 | -2.239 | ||||||
P值 | 0.429 | 0.029 | 0.082 | <0.001 | 0.551 | 0.028 |
Table 2 Comparison of sleep breathing parameters between the two groups before and after the intervention
组别 | 例数 | AHI(次/h) | SpO2(%) | |||||||||
---|---|---|---|---|---|---|---|---|---|---|---|---|
干预前 | 干预6周后 | t配对值 | P值 | 干预前 | 干预6周后 | t配对值 | P值 | |||||
对照组 | 34 | 30.25±18.65 | 18.27±10.36 | 7.507 | <0.001 | 90.82±2.82 | 94.35±1.95 | -12.294 | <0.001 | |||
试验组 | 35 | 31.06±20.22 | 15.85±9.97 | 7.391 | <0.001 | 91.49±3.08 | 96.34±1.51 | -12.994 | <0.001 | |||
t值 | -0.617 | -0.984 | 0.931 | 4.740 | ||||||||
P值 | 0.539 | 0.329 | 0.355 | <0.001 | ||||||||
组别 | LSaO2(%) | ODI(次/h) | ||||||||||
干预前 | 干预6周后 | t配对值 | P值 | 干预前 | 干预6周后 | t配对值 | P值 | |||||
对照组 | 77.76±8.58 | 88.03±4.74 | -11.916 | <0.001 | 30.74±18.91 | 20.12±12.33 | 8.073 | <0.001 | ||||
试验组 | 78.89±8.24 | 90.69±3.21 | -12.377 | <0.001 | 30.96±18.84 | 14.00±8.53 | 8.488 | <0.001 | ||||
t值 | 0.554 | 2.734 | 0.048 | -2.402 | ||||||||
P值 | 0.582 | 0.008 | 0.962 | 0.019 | ||||||||
组别 | 深睡眠比例(N3期睡眠占总睡眠时间比例)(%) | 觉醒指数(次/h) | ESS评分(分) | |||||||||
干预前 | 干预6周后 | t配对值 | P值 | 干预前 | 干预6周后 | t配对值 | P值 | 干预前 | 干预6周后 | t配对值 | P值 | |
对照组 | 16.08±8.50 | 24.72±5.50 | -13.505 | <0.001 | 20.24±7.10 | 10.38±3.49 | 8.895 | <0.001 | 13.44±4.08 | 8.68±2.28 | 10.807 | <0.001 |
试验组 | 14.54±7.50 | 27.47±4.71 | -18.041 | <0.001 | 16.60±9.81 | 5.99±3.88 | 7.410 | <0.001 | 12.80±4.78 | 7.26±2.93 | 12.756 | <0.001 |
t值 | -0.796 | 2.237 | -1.764 | -4.933 | -0.600 | -2.239 | ||||||
P值 | 0.429 | 0.029 | 0.082 | <0.001 | 0.551 | 0.028 |
组别 | 例数 | FEV1(L) | FVC(L) | FEV1/FVC(%) | |||||||||
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
干预前 | 干预6周后 | t配对值 | P值 | 干预前 | 干预6周后 | t配对值 | P值 | 干预前 | 干预6周后 | t配对值 | P值 | ||
对照组 | 34 | 1.54±0.38 | 2.79±0.34 | -17.453 | <0.001 | 1.95±0.47 | 3.36±0.55 | -14.828 | <0.001 | 0.55±0.09 | 0.83±0.06 | -16.782 | <0.001 |
试验组 | 35 | 1.61±0.60 | 2.98±0.33 | -15.118 | <0.001 | 2.14±0.62 | 3.63±0.44 | -14.544 | <0.001 | 0.55±0.10 | 0.87±0.08 | -20.798 | <0.001 |
t值 | 0.577 | 2.372 | 1.444 | 2.183 | -0.011 | 2.366 | |||||||
P值 | 0.566 | 0.021 | 0.154 | 0.033 | 0.991 | 0.021 |
Table 3 Comparison of pulmonary function indexes between the two groups before and after intervention
组别 | 例数 | FEV1(L) | FVC(L) | FEV1/FVC(%) | |||||||||
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
干预前 | 干预6周后 | t配对值 | P值 | 干预前 | 干预6周后 | t配对值 | P值 | 干预前 | 干预6周后 | t配对值 | P值 | ||
对照组 | 34 | 1.54±0.38 | 2.79±0.34 | -17.453 | <0.001 | 1.95±0.47 | 3.36±0.55 | -14.828 | <0.001 | 0.55±0.09 | 0.83±0.06 | -16.782 | <0.001 |
试验组 | 35 | 1.61±0.60 | 2.98±0.33 | -15.118 | <0.001 | 2.14±0.62 | 3.63±0.44 | -14.544 | <0.001 | 0.55±0.10 | 0.87±0.08 | -20.798 | <0.001 |
t值 | 0.577 | 2.372 | 1.444 | 2.183 | -0.011 | 2.366 | |||||||
P值 | 0.566 | 0.021 | 0.154 | 0.033 | 0.991 | 0.021 |
组别 | 例数 | MEP | MIP | ||||||
---|---|---|---|---|---|---|---|---|---|
干预前 | 干预6周后 | t配对值 | P值 | 干预前 | 干预6周后 | t配对值 | P值 | ||
对照组 | 34 | 50.29±15.52 | 115.26±14.22 | -17.200 | <0.001 | 41.79±9.17 | 88.71±7.96 | -24.956 | <0.001 |
试验组 | 35 | 52.86±21.54 | 126.86±14.22 | -22.261 | <0.001 | 40.83±9.50 | 95.34±10.91 | -21.452 | <0.001 |
t值 | 0.566 | 2.816 | -0.429 | 2.880 | |||||
P值 | 0.574 | 0.006 | 0.669 | 0.005 |
Table 4 Comparison of respiratory muscle function indexes between the two groups before and after intervention
组别 | 例数 | MEP | MIP | ||||||
---|---|---|---|---|---|---|---|---|---|
干预前 | 干预6周后 | t配对值 | P值 | 干预前 | 干预6周后 | t配对值 | P值 | ||
对照组 | 34 | 50.29±15.52 | 115.26±14.22 | -17.200 | <0.001 | 41.79±9.17 | 88.71±7.96 | -24.956 | <0.001 |
试验组 | 35 | 52.86±21.54 | 126.86±14.22 | -22.261 | <0.001 | 40.83±9.50 | 95.34±10.91 | -21.452 | <0.001 |
t值 | 0.566 | 2.816 | -0.429 | 2.880 | |||||
P值 | 0.574 | 0.006 | 0.669 | 0.005 |
[1] |
|
[2] |
崔丽颖,袁烨,赵秉清,等. 无创正压气道通气对老年脑梗死并阻塞性睡眠呼吸暂停患者预后的影响[J]. 中华老年心脑血管病杂志,2017,19(1):55-59. DOI:10.3969/j.issn.1009-0126.2017.01.015.
|
[3] |
|
[4] |
|
[5] |
|
[6] |
|
[7] |
|
[8] |
|
[9] |
中华医学会全国第四届脑血管病学术会议组.各类脑血管病诊断要点[J].中华神经科杂志,1996,26(6):379.
|
[10] |
American Academy of Sleep Medicine.睡眠障碍国际分类[M]. 高和,译. 3版. 北京:人民卫生出版社,2017:2-22.
|
[11] |
|
[12] |
|
[13] |
|
[14] |
|
[15] |
|
[16] |
|
[17] |
|
[18] |
|
[19] |
|
[20] |
刘伟利,张晓晓,李飞翔,等. 阈值压力负荷呼吸肌训练在脑外伤患者呼吸功能康复中的应用研究[J].中华全科医学,2021,19(8):4. DOI:10.16766/j.cnki.issn.1674-4152.002062.
|
[21] |
时惠,刘玲,祖菲娅·吐尔迪. 阈值压力负荷呼吸肌训练对脑卒中患者康复疗效的Meta分析[J]. 中国康复理论与实践,2016,22(9):1069-1074. DOI:10.3969/j.issn.1006-9771.2016.09.019.
|
[22] |
|
[23] |
|
[24] |
董校玉,赵倩. 阈值压力负荷呼吸肌训练对慢性阻塞性肺疾病患者肺功能、运动耐力及呼吸肌肌力的影响[J].保健医学研究与实践,2022,19(7):101-104. DOI:10.11986/j.issn.1673-873X.2022.07.026.
|
[25] |
|
[26] |
|
[27] |
|
[28] |
|
[1] | XIAO Yuqian, BAI Yanjie, WANG Yan, SUN Kexin, WAN Jun, CHEN Shuying, CHEN Limin. Research Progress of Astrocyte-derived Extracellular Vesicles in Post-stroke Cognitive Impairment [J]. Chinese General Practice, 2024, 27(20): 2551-2556. |
[2] | QIAN Zhen, LU Tongbo, HE Jun, ZHU Haiying, WANG Jin, GONG Zunke. Efficacy and Preliminary Mechanism of Precise Exercise Prescriptions for Anxiety, Depression, and Cognitive Function in Patients with Stroke: a Randomized Controlled Trial [J]. Chinese General Practice, 2024, 27(20): 2445-2450. |
[3] | ZENG Fanyan, YANG Xuezhi, LIU Xingyu, MO Jiali, LIU Zuting, LU Yi, YI Yingping, KUANG Jie. Association between Rainfall and Stroke Admissions: Based on Distributional Lag Nonlinear Modeling [J]. Chinese General Practice, 2024, 27(20): 2458-2465. |
[4] | YANG Lihong, ZHANG Chao, LI Zefang, YANG Chen, WANG Fei, DU Yuzheng, SHI Huiyan. A Case Registry Study of Acupuncture Treatment for Stroke: Data Elements and Definitions [J]. Chinese General Practice, 2024, 27(16): 2023-2032. |
[5] | NIU Jingyuan, CHEN Huisheng, YU Jiaxiang, CUI Yu. Ligustrazine Injection in the Treatment of Acute Ischemic Stroke: a Bayesian Network Meta-analysis [J]. Chinese General Practice, 2024, 27(14): 1761-1774. |
[6] | GAO Kaiqian, YANG Yu, HU Yanfang, DONG Fafa. Nested Case-control Study on the Impact of Stress Hyperglycemia Ratio on the Recurrence of Mild Acute Ischemic Stroke in the Elderly [J]. Chinese General Practice, 2024, 27(14): 1692-1698. |
[7] | XIE Yi, XU Junma, XU Fangqin, LI Chao, CHEN Chen, SHAO Chan. Predictive Value of Sarcopenia Index for Prognosis in Elderly Patients with Acute Ischemic Stroke [J]. Chinese General Practice, 2024, 27(11): 1326-1330. |
[8] | WANG Xiaoxuan, ZHANG Zhenxiang, ZHAO Zhixin, JIANG Hu, WANG Jiajia, LIN Beilei, WANG Wenna, CHEN Suyan. Meta-integration of Qualitative Research on Fatigue Experience in Patients with Post-stroke Fatigue [J]. Chinese General Practice, 2024, 27(09): 1134-1141. |
[9] | CHEN Wenjin, CHEN Piaoying, YANG Xiaohua, CHEN Yifan, CAI Yefeng, NI Xiaojia. Advance in Epidemiologic Studies of Dietary Patterns Associated with Cerebrovascular Diseases [J]. Chinese General Practice, 2024, 27(08): 900-907. |
[10] | ZHAO Yuan, LIU Shanghong, ZHANG Yanfang, MA Lixu, LI Hong, LI Xiaohua, TIAN Yuan, GUO Zhongqin, LIANG Peifeng. Characteristics of Gender, Age, Spatial and Temporal Distribution of Stroke Hospitalization Cases Based on the Data of 190 000 Patients in Ningxia Region [J]. Chinese General Practice, 2024, 27(08): 915-920. |
[11] | YUAN Quan, LU Haiying, WANG Yi, LIU Yunxiao, YU Jiaqin, TIAN Fengzhao, LI Yao. Telemedicine Management in Stabilized Respiratory Rehabilitation of Elderly Patients with Moderate-to-severe Chronic Obstructive Pulmonary Disease: a Randomized Controlled Trial [J]. Chinese General Practice, 2024, 27(06): 711-716. |
[12] | LIANG Tianyi, LIU Peng. Study on Stroke-rehabilitative Families under Chronic Illness Narratives: a Field Study Based on Rehabilitation Hall of Traditional Chinese Medicine Hospital in T City, Hebei Province [J]. Chinese General Practice, 2024, 27(04): 502-508. |
[13] | XUE Chao, LI Juan, FANG Qian, YU Jie, HAO Mingqing. Prevalence and Trends for Post-stroke Fatigue in China: a Meta-analysis [J]. Chinese General Practice, 2024, 27(03): 364-374. |
[14] | HU Qianqian, ZHOU Tong, LIU Zhihui, PAN Ye, WANG Liuyi. Analysis of the Current Status of Ischemic Stroke Co-morbidity and Co-morbidity Patterns in Middle-aged Based on Data from Tertiary Hospitals in Henan Province [J]. Chinese General Practice, 2024, 27(02): 201-207. |
[15] | BAI Haiwei, MI Xiaokun, LIU Qingrui, ZHU Lin, WANG Yingnan, LIU Junyan, HAN Ying. Predictive Value of Serum Uric Acid in Perioperative Acute Ischemic Stroke in Patients with Non-small Cell Lung Cancer [J]. Chinese General Practice, 2023, 26(36): 4545-4551. |
Viewed | ||||||
Full text |
|
|||||
Abstract |
|
|||||