Chinese General Practice ›› 2023, Vol. 26 ›› Issue (36): 4581-4586.DOI: 10.12114/j.issn.1007-9572.2023.0220
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Received:
2023-04-02
Revised:
2023-06-10
Published:
2023-12-20
Online:
2023-07-19
Contact:
YU Xiaohui
通讯作者:
于晓辉
作者简介:
基金资助:
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URL: https://www.chinagp.net/EN/10.12114/j.issn.1007-9572.2023.0220
性别 | 年份 | 发病率 | 死亡率 | DALY率 | |||
---|---|---|---|---|---|---|---|
粗率 | 标化率 | 粗率 | 标化率 | 粗率 | 标化率 | ||
男性 | 1990年 | 1.71 | 1.72 | 0.42 | 0.94 | 18.21 | 24.06 |
2019年 | 3.99 | 3.35 | 0.35 | 0.47 | 17.71 | 18.45 | |
变化率(%) | 133.33 | 94.76 | -16.67 | -50.00 | -2.75 | -23.32 | |
女性 | 1990年 | 1.19 | 1.21 | 0.52 | 0.84 | 21.47 | 25.50 |
2019年 | 3.24 | 2.66 | 0.31 | 0.30 | 14.92 | 14.78 | |
变化率(%) | 172.27 | 119.83 | -40.38 | -64.29 | -30.51 | -42.04 | |
总人群 | 1990年 | 1.45 | 1.47 | 0.47 | 0.86 | 19.79 | 24.47 |
2019年 | 3.62 | 3.01 | 0.33 | 0.35 | 16.34 | 16.31 | |
变化率(%) | 149.66 | 104.76 | -29.79 | -59.30 | -17.43 | -33.35 |
Table 1 Disease burden of inflammatory bowel disease in China from 1990 to 2019
性别 | 年份 | 发病率 | 死亡率 | DALY率 | |||
---|---|---|---|---|---|---|---|
粗率 | 标化率 | 粗率 | 标化率 | 粗率 | 标化率 | ||
男性 | 1990年 | 1.71 | 1.72 | 0.42 | 0.94 | 18.21 | 24.06 |
2019年 | 3.99 | 3.35 | 0.35 | 0.47 | 17.71 | 18.45 | |
变化率(%) | 133.33 | 94.76 | -16.67 | -50.00 | -2.75 | -23.32 | |
女性 | 1990年 | 1.19 | 1.21 | 0.52 | 0.84 | 21.47 | 25.50 |
2019年 | 3.24 | 2.66 | 0.31 | 0.30 | 14.92 | 14.78 | |
变化率(%) | 172.27 | 119.83 | -40.38 | -64.29 | -30.51 | -42.04 | |
总人群 | 1990年 | 1.45 | 1.47 | 0.47 | 0.86 | 19.79 | 24.47 |
2019年 | 3.62 | 3.01 | 0.33 | 0.35 | 16.34 | 16.31 | |
变化率(%) | 149.66 | 104.76 | -29.79 | -59.30 | -17.43 | -33.35 |
分类 | 区间段(年) | APC(%) | t值 | P值 |
---|---|---|---|---|
男性 | 1990—1996 | 1.86 | 77.1 | <0.001 |
1996—1999 | 5.66 | 42.7 | <0.001 | |
1999—2006 | 1.56 | 73.6 | <0.001 | |
2006—2009 | 2.77 | 22.0 | <0.001 | |
2009—2015 | 1.74 | 63.1 | <0.001 | |
2015—2019 | 2.52 | 62.9 | <0.001 | |
女性 | 1990—1995 | 1.63 | 6.8 | <0.001 |
1995—1999 | 7.19 | 13.9 | <0.001 | |
1999—2019 | 2.16 | 82.7 | <0.001 | |
总体 | 1990—1995 | 1.68 | 27.8 | <0.001 |
1995—2000 | 5.26 | 66.1 | <0.001 | |
2000—2005 | 1.31 | 17.5 | <0.001 | |
2005—2010 | 2.54 | 33.9 | <0.001 | |
2010—2015 | 1.73 | 23.2 | <0.001 | |
2015—2019 | 2.55 | 33.4 | <0.001 |
Table 2 Joinpoint regression analysis of standardized incidence of inflammatory bowel disease in China from 1990 to 2019
分类 | 区间段(年) | APC(%) | t值 | P值 |
---|---|---|---|---|
男性 | 1990—1996 | 1.86 | 77.1 | <0.001 |
1996—1999 | 5.66 | 42.7 | <0.001 | |
1999—2006 | 1.56 | 73.6 | <0.001 | |
2006—2009 | 2.77 | 22.0 | <0.001 | |
2009—2015 | 1.74 | 63.1 | <0.001 | |
2015—2019 | 2.52 | 62.9 | <0.001 | |
女性 | 1990—1995 | 1.63 | 6.8 | <0.001 |
1995—1999 | 7.19 | 13.9 | <0.001 | |
1999—2019 | 2.16 | 82.7 | <0.001 | |
总体 | 1990—1995 | 1.68 | 27.8 | <0.001 |
1995—2000 | 5.26 | 66.1 | <0.001 | |
2000—2005 | 1.31 | 17.5 | <0.001 | |
2005—2010 | 2.54 | 33.9 | <0.001 | |
2010—2015 | 1.73 | 23.2 | <0.001 | |
2015—2019 | 2.55 | 33.4 | <0.001 |
分类 | 区间段(年) | APC(%) | t值 | P值 |
---|---|---|---|---|
男性 | 1990—2004 | -1.95 | -30.2 | <0.001 |
2004—2008 | -5.74 | -14.1 | <0.001 | |
2008—2016 | -4.14 | -47.1 | <0.001 | |
2016—2019 | -2.14 | -5.4 | <0.001 | |
女性 | 1990—2004 | -1.83 | -26.5 | <0.001 |
2004—2008 | -8.98 | -16.8 | <0.001 | |
2008—2013 | -7.87 | -33.2 | <0.001 | |
2013—2016 | -6.23 | -8.6 | <0.001 | |
2016—2019 | -0.41 | -0.9 | <0.001 | |
总体 | 1990—2004 | -1.72 | -32.6 | <0.001 |
2004—2007 | -7.82 | -9.5 | <0.001 | |
2007—2013 | -6.36 | -47.2 | <0.001 | |
2013—2016 | -5.04 | -9.4 | <0.001 | |
2016—2019 | -1.13 | -3.5 | <0.001 |
Table 3 Joinpoint regression analysis of standardized mortality of inflammatory bowel disease in China from 1990 to 2019
分类 | 区间段(年) | APC(%) | t值 | P值 |
---|---|---|---|---|
男性 | 1990—2004 | -1.95 | -30.2 | <0.001 |
2004—2008 | -5.74 | -14.1 | <0.001 | |
2008—2016 | -4.14 | -47.1 | <0.001 | |
2016—2019 | -2.14 | -5.4 | <0.001 | |
女性 | 1990—2004 | -1.83 | -26.5 | <0.001 |
2004—2008 | -8.98 | -16.8 | <0.001 | |
2008—2013 | -7.87 | -33.2 | <0.001 | |
2013—2016 | -6.23 | -8.6 | <0.001 | |
2016—2019 | -0.41 | -0.9 | <0.001 | |
总体 | 1990—2004 | -1.72 | -32.6 | <0.001 |
2004—2007 | -7.82 | -9.5 | <0.001 | |
2007—2013 | -6.36 | -47.2 | <0.001 | |
2013—2016 | -5.04 | -9.4 | <0.001 | |
2016—2019 | -1.13 | -3.5 | <0.001 |
分类 | 区间段(年) | APC(%) | t值 | P值 |
---|---|---|---|---|
男性 | 1990—1996 | -1.81 | -19.2 | <0.001 |
1996—2000 | 0.19 | 0.8 | <0.001 | |
2000—2004 | -1.11 | -5.3 | <0.001 | |
2004—2007 | -3.39 | -9.3 | <0.001 | |
2007—2015 | -2.49 | -54.5 | <0.001 | |
2015—2019 | -0.96 | -7.8 | <0.001 | |
女性 | 1990—1996 | -2.55 | -26.4 | <0.001 |
1996—2000 | -0.40 | -1.5 | <0.001 | |
2000—2004 | -2.97 | -11.7 | <0.001 | |
2004—2007 | -5.55 | -10.4 | <0.001 | |
2007—2015 | -3.83 | -46.5 | <0.001 | |
2015—2019 | -0.63 | -2.6 | <0.001 | |
总体 | 1990—1996 | -2.20 | -25.7 | <0.001 |
1996—2000 | -0.00 | 0.0 | <0.001 | |
2000—2004 | -1.95 | -8.7 | <0.001 | |
2004—2007 | -4.47 | -10.3 | <0.001 | |
2007—2015 | -3.16 | -49.1 | <0.001 | |
2015—2019 | -0.72 | -4.0 | <0.001 |
Table 4 Joinpoint regression analysis of standardized DALY rate of inflammatory bowel disease in China from 1990 to 2019
分类 | 区间段(年) | APC(%) | t值 | P值 |
---|---|---|---|---|
男性 | 1990—1996 | -1.81 | -19.2 | <0.001 |
1996—2000 | 0.19 | 0.8 | <0.001 | |
2000—2004 | -1.11 | -5.3 | <0.001 | |
2004—2007 | -3.39 | -9.3 | <0.001 | |
2007—2015 | -2.49 | -54.5 | <0.001 | |
2015—2019 | -0.96 | -7.8 | <0.001 | |
女性 | 1990—1996 | -2.55 | -26.4 | <0.001 |
1996—2000 | -0.40 | -1.5 | <0.001 | |
2000—2004 | -2.97 | -11.7 | <0.001 | |
2004—2007 | -5.55 | -10.4 | <0.001 | |
2007—2015 | -3.83 | -46.5 | <0.001 | |
2015—2019 | -0.63 | -2.6 | <0.001 | |
总体 | 1990—1996 | -2.20 | -25.7 | <0.001 |
1996—2000 | -0.00 | 0.0 | <0.001 | |
2000—2004 | -1.95 | -8.7 | <0.001 | |
2004—2007 | -4.47 | -10.3 | <0.001 | |
2007—2015 | -3.16 | -49.1 | <0.001 | |
2015—2019 | -0.72 | -4.0 | <0.001 |
指标 | AAPC(95%CI)(%) | t值 | P值 |
---|---|---|---|
标化发病率 | |||
男性 | 2.3(2.3,2.4) | 108.1 | <0.001 |
女性 | 2.7(2.6,2.9) | 33.0 | <0.001 |
合计 | 2.5(2.4,2.6) | 83.2 | <0.001 |
标化死亡率 | |||
男性 | -3.1(-3.3,-3.0) | -38.6 | <0.001 |
女性 | -4.2(-4.5,-4.0) | -33.0 | <0.001 |
合计 | -3.6(-3.8,-3.4) | -31.5 | <0.001 |
标化DALY率 | |||
男性 | -1.7(-1.8,-1.5) | -25.9 | <0.001 |
女性 | -2.7(-2.9,-2.6) | -30.8 | <0.001 |
合计 | -2.2(-2.3,-2.0) | -30.0 | <0.001 |
Table 5 Joinpoint regression analysis of inflammatory bowel disease burden
指标 | AAPC(95%CI)(%) | t值 | P值 |
---|---|---|---|
标化发病率 | |||
男性 | 2.3(2.3,2.4) | 108.1 | <0.001 |
女性 | 2.7(2.6,2.9) | 33.0 | <0.001 |
合计 | 2.5(2.4,2.6) | 83.2 | <0.001 |
标化死亡率 | |||
男性 | -3.1(-3.3,-3.0) | -38.6 | <0.001 |
女性 | -4.2(-4.5,-4.0) | -33.0 | <0.001 |
合计 | -3.6(-3.8,-3.4) | -31.5 | <0.001 |
标化DALY率 | |||
男性 | -1.7(-1.8,-1.5) | -25.9 | <0.001 |
女性 | -2.7(-2.9,-2.6) | -30.8 | <0.001 |
合计 | -2.2(-2.3,-2.0) | -30.0 | <0.001 |
年龄(岁) | AAPC(95%CI)(%) | t值 | P值 |
---|---|---|---|
15~19 | 2.7(2.5,2.9) | 28.5 | <0.001 |
20~24 | 2.9(2.7,3.0) | 50.0 | <0.001 |
25~29 | 2.8(2.7,2.9) | 46.0 | <0.001 |
30~34 | 2.6(2.5,2.8) | 37.7 | <0.001 |
35~39 | 2.6(2.5,2.6) | 101.1 | <0.001 |
40~44 | 2.5(2.5,2.6) | 88.5 | <0.001 |
45~49 | 2.5(2.4,2.6) | 81.5 | <0.001 |
50~54 | 2.4(2.4,2.5) | 79.7 | <0.001 |
55~59 | 2.3(2.2,2.3) | 106.3 | <0.001 |
60~64 | 2.2(2.2,2.3) | 95.6 | <0.001 |
65~69 | 2.2(2.1,2.2) | 81.2 | <0.001 |
70~74 | 2.1(2.0,2.1) | 69.4 | <0.001 |
75~79 | 1.9(1.8,2.0) | 47.2 | <0.001 |
80~84 | 1.8(1.7,1.9) | 50.4 | <0.001 |
85~89 | 1.7(1.6,1.8) | 38.0 | <0.001 |
90~94 | 1.7(1.6,1.7) | 49.2 | <0.001 |
≥95 | 1.6(1.5,1.7) | 41.0 | <0.001 |
Table 6 Age grouping of standardized incidence of inflammatory bowel disease in China from 1990 to 2019
年龄(岁) | AAPC(95%CI)(%) | t值 | P值 |
---|---|---|---|
15~19 | 2.7(2.5,2.9) | 28.5 | <0.001 |
20~24 | 2.9(2.7,3.0) | 50.0 | <0.001 |
25~29 | 2.8(2.7,2.9) | 46.0 | <0.001 |
30~34 | 2.6(2.5,2.8) | 37.7 | <0.001 |
35~39 | 2.6(2.5,2.6) | 101.1 | <0.001 |
40~44 | 2.5(2.5,2.6) | 88.5 | <0.001 |
45~49 | 2.5(2.4,2.6) | 81.5 | <0.001 |
50~54 | 2.4(2.4,2.5) | 79.7 | <0.001 |
55~59 | 2.3(2.2,2.3) | 106.3 | <0.001 |
60~64 | 2.2(2.2,2.3) | 95.6 | <0.001 |
65~69 | 2.2(2.1,2.2) | 81.2 | <0.001 |
70~74 | 2.1(2.0,2.1) | 69.4 | <0.001 |
75~79 | 1.9(1.8,2.0) | 47.2 | <0.001 |
80~84 | 1.8(1.7,1.9) | 50.4 | <0.001 |
85~89 | 1.7(1.6,1.8) | 38.0 | <0.001 |
90~94 | 1.7(1.6,1.7) | 49.2 | <0.001 |
≥95 | 1.6(1.5,1.7) | 41.0 | <0.001 |
年龄(岁) | AAPC(95%CI)(%) | t值 | P值 |
---|---|---|---|
15~19 | -4.2(-4.0,-4.4) | -48.4 | <0.001 |
20~24 | -3.4(-3.8,-3.0) | -16.1 | <0.001 |
25~29 | -3.8(-4.2,-3.3) | -16.8 | <0.001 |
30~34 | -3.7(-4.1,-3.2) | -15.4 | <0.001 |
35~39 | -3.8(-4.0,-3.5) | -25.4 | <0.001 |
40~44 | -3.5(-3.8,-3.3) | -26.6 | <0.001 |
45~49 | -3.7(-4.2,-3.2) | -14.0 | <0.001 |
50~54 | -3.6(-3.8,-3.4) | -31.6 | <0.001 |
55~59 | -3.4(-3.8,-3.1) | -19.9 | <0.001 |
60~64 | -3.4(-3.6,-3.2) | -29.6 | <0.001 |
65~69 | -3.3(-3.6,-3.2) | -27.7 | <0.001 |
70~74 | -3.4(-3.6,-3.2) | -48.3 | <0.001 |
75~79 | -3.5(-3.6,-3.2) | -33.3 | <0.001 |
80~84 | -3.7(-3.6,-3.2) | -19.2 | <0.001 |
85~89 | -3.5(-3.6,-3.2) | -22.7 | <0.001 |
90~94 | -3.3(-3.6,-3.2) | -20.3 | <0.001 |
≥95 | -2.5(-2.8,-2.1) | -14.8 | <0.001 |
Table 7 Age grouping of standardized mortality of inflammatory bowel disease in China from 1990 to 2019
年龄(岁) | AAPC(95%CI)(%) | t值 | P值 |
---|---|---|---|
15~19 | -4.2(-4.0,-4.4) | -48.4 | <0.001 |
20~24 | -3.4(-3.8,-3.0) | -16.1 | <0.001 |
25~29 | -3.8(-4.2,-3.3) | -16.8 | <0.001 |
30~34 | -3.7(-4.1,-3.2) | -15.4 | <0.001 |
35~39 | -3.8(-4.0,-3.5) | -25.4 | <0.001 |
40~44 | -3.5(-3.8,-3.3) | -26.6 | <0.001 |
45~49 | -3.7(-4.2,-3.2) | -14.0 | <0.001 |
50~54 | -3.6(-3.8,-3.4) | -31.6 | <0.001 |
55~59 | -3.4(-3.8,-3.1) | -19.9 | <0.001 |
60~64 | -3.4(-3.6,-3.2) | -29.6 | <0.001 |
65~69 | -3.3(-3.6,-3.2) | -27.7 | <0.001 |
70~74 | -3.4(-3.6,-3.2) | -48.3 | <0.001 |
75~79 | -3.5(-3.6,-3.2) | -33.3 | <0.001 |
80~84 | -3.7(-3.6,-3.2) | -19.2 | <0.001 |
85~89 | -3.5(-3.6,-3.2) | -22.7 | <0.001 |
90~94 | -3.3(-3.6,-3.2) | -20.3 | <0.001 |
≥95 | -2.5(-2.8,-2.1) | -14.8 | <0.001 |
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