Abstract: Background　Mental disorders are often comorbidities with alcohol use disorders. At present，there are few reports on the influencing factors of this phenomenon, and the conclusions are inconsistent. Clinicians pay more attention to the diagnosis of mental disorders and ignore the existence of comorbidity. Comorbidity are often missed. Objective　To investigate the prevalence of alcohol use disorder （AUD） and associated factors among inpatients with mental disorders.Methods　We enrolled 710 inpatients with mental disorders from Heibei Mental Health Center，from October 10 to October 17，2016.We employed the diagnostic and statistical manual of mental disorders-fifth edition （DSM-5） to assess the types of mental disorders，and according to the results，assigned 171 with AUD and 539 without to the comorbidity group and non-comorbidity group，respectively.We used a self-developed baseline questionnaire to collect their baseline data 〔including sex，age，marital status，education，living style，family relationship，occupation，pre illness personality，alcohol family history，diagnosis，risk assessment （such as impulsive，outward，self injury，suicide）〕.Results　The prevalence of AUD in inpatients with schizophrenia spectrum disorders，depressive disorders，bipolar and related disorders，and other types of mental disorders was 19.6% （59 cases），27.2% （44 cases），34.5% （51 cases），17.2% （17 cases），respectively.Inpatients with AUD and those without showed significant differences in the distribution of sex，status of family relations，occupation，family history of alcoholism，distribution of mental disorders and the proportion of impulsiveness （P<0.05）.Multivariate Logistic regression analysis showed that male 〔OR=7.57，95%CI （4.63，12.37）〕，inharmonious family relationship 〔OR=2.35，95%CI （1.36，4.08）〕，unemployed 〔OR=3.75，95%CI （1.98，7.10）〕，depressive disorders 〔OR=2.81，95%CI （1.40，5.63）〕and risk of impulse-control disorders 〔OR=1.72，95%CI （1.12，2.65）〕were the associated factors for the prevalence of AUD in inpatients with mental disorders （P<0.05）.Conclusion　The prevalence of AUD is high in inpatients with mental disorders.Male，inharmonious family relationship，unemployed，depressive disorders and risk of impulse-control disorders may be the factors associated with it.

Key words: Alcohol-related disorders, Mental disorders, Comorbidity, Root cause analysis

摘要： 背景　精神障碍常与酒精使用障碍共病，但其影响因素报道不一，且住院患者共病报道较少，而临床医生常注重治疗单一精神障碍，而忽视共病的存在，容易导致漏诊。目的　调查住院精神障碍患者共病酒精使用障碍的现况，并分析其影响因素。方法　选取2016年10月10—17日在河北省精神卫生中心住院的精神障碍患者710例，根据是否共病酒精使用障碍分为共病组（171例）及非共病组（539例）。以《精神障碍诊断与统计手册（第五版）》（DSM-5）为诊断工具对精神障碍患者进行疾病诊断。采用自行设计的一般情况调查表收集患者的一般资料，包括性别、年龄、婚姻状况、受教育程度、居住方式、家庭关系、职业、病前性格、嗜酒家族史、诊断、风险评估（有无冲动、外走、自伤、自杀等行为）。结果　精神分裂症共病酒精使用障碍发生率为19.6%（59/301）；抑郁症共病酒精使用障碍发生率为27.2%（44/162）；双相情感障碍共病酒精使用障碍发生率为34.5%（51/148）；其他精神障碍共病酒精使用障碍发生率为17.2%（17/99）。两组性别、家庭关系、职业、嗜酒家族史、诊断分布、冲动所占比例比较，差异均有统计学意义（P<0.05）。多因素Logistic回归分析显示，男性〔OR=7.57，95%CI（4.63，12.37）〕、家庭关系不和睦〔OR=2.35，95%CI（1.36，4.08）〕、待业〔OR=3.75，95%CI（1.98，7.10）〕、抑郁症〔OR=2.81，95%CI（1.40，5.63）〕及冲动〔OR=1.72，95%CI（1.12，2.65）〕是精神障碍患者共病酒精使用障碍的影响因素（P<0.05）。结论　精神障碍共病酒精使用障碍的比例较高，且男性、家庭关系不和睦、待业、抑郁症及冲动是其影响因素。

关键词: 酒精相关性障碍, 精神障碍, 共病现象, 影响因素分析