关键词: 胰腺炎, 糖尿病, 疾病特征

Abstract: Objective　 To investigate the clinical characteristics of acute pancreatitis（AP） among patients with diabetes mellitus（DM）．Methods　We enrolled 329 cases of AP from Guangdong General Hospital from 2013 to 2016，including 80 with a history of DM（DM with AP group）and 249 without（simple AP group）. Based on reviewing the medical records，we collected the clinical data about sex，age，past medical history，etiology，levels of triacylglycerol（TG） and total cholesterol（TC），length of stay（LOS），incidence of mortality，severity levels of AP evaluated by the Chinese Guidelines for the Management of Acute Pancreatitis（Shanghai，2013） and severity scores of conditions〔comprehensively evaluated by Ranson's score，APACHE-Ⅱ score，bedside index for severity in acute pancreatitis （BISAP） score，and modified CT severity index（MCTSI）〕，complications and compared them between the groups. Results　 Compared with DM with AP group，simple AP group had lower rate of patients with a history of previous pancreatitis，and lower levels of TG and TC（P<0.05）. The distribution of etiologies differed significantly between the two groups（P<0.05）.However，two groups showed no significant differences in the distribution of sex，age，LOS，mortality，severity levels of AP and severity scores of conditions（assessed by Ranson's score，APACHE-Ⅱscore，BISAP score，and MCTSI），and incidence of the aforementioned local and systemic complications（P>0.05）. Conclusion　Diabetic status has little effect on the severity of AP，the incidence of local and systemic complications caused by AP，the mortality as well as LOS. 

Key words: Pancreatitis, Diabetes mellitus, Disease attributes