关键词: 针灸疗法, 上工治未病, 脂质

Abstract: Preventive acupuncture and moxibustion，important interventions for preventive treatment of disease，refer to using acupuncture and moxibustion to control the risk factors to prevent the onset of disease possibly.The central nervous system（especially the appetite-regulating center in the hypothalamus），plays an important role in the regulation of lipid metabolism，a complicated process with multiple signals and pathways，demonstrating as periphery feeding signals leading to integration and coordination of brain-mediated responses and control of energy homeostasis by neuropeptide pathways.Aquaporin water channels in human salivary glands are of great significance for lipid metabolism.Studies show that saliva contains a variety of neuropeptides，many of which are closely related to feeding，lipid metabolism，and their receptors are widely distributed in the salivary glands or the nerves innervating the salivary glands.Studies support that preventive acupuncture and moxibustion are contributive to the improvement of lipid metabolism.We analyzed the mechanism of action of preventive acupuncture and moxibustion in lipid metabolism regulation from the neurobiological perspective（interpreting the role of involved neuropeptide-water channels in human salivary glands-appetite-regulating center） in an objective and scientific manner.

Key words: Acupuncture-moxibustion, Superior treat before sick, Body fat