关键词: 咬伤和蛰伤, 蜱, 感染, 病例报告, 历史文献

Abstract: Objective　To investigate the injury，treatment and prevention secondary to infection from tick bites.Methods　Based on literature review，the clinical data（sex，age，symptoms，signs，laboratory examination，treatment） of 3 children with tick bite infection admitted to the Children's Hospital of Nanjing Medical University were analyzed from July 6 2018 to July 19 2018.Results　Among the 3 cases，1 was male and 2 was female；three children were aged 1 year and 7 months，5 years and 3 months and 15 years and 6 months，respectively.Three patients all had fever with body temperature exceeding 38.5 ℃.
In one of the cases，the biting tick was removed by surgery followed by debridement of the wounded area.This case had a good outcome with short course and low medical expenses.The other two cases were siblings without findings of specific site of the biting ticks.These two patients presented with fever，and were diagnosed with severe fever with thrombocytopenia syndrome virus（SFTSV） infection by the center for disease control and prevention subsequently.The little brother bacame better after conventional therapy.The big sister with worse condition became better as well after treating with ribavirin and r-globulin of 2 g/kg.Conclusion　Removing the ticks in time is of good efficacy.For patients who can not find the bite site，if fever occurs，white blood cell count and platelet count decrease，their blood should be sent to the center for disease control and prevention in time to identify the cause，receive early treatment as soon as possible to reduce complications.

Key words: Bites and stings, Ticks, Infection, Case reports, Historical article