关键词: ADH分泌不当综合征, 低钠血症, 病例报告, 历史文献

Abstract: Syndrome of inappropriate antidiuretic hormone secretion （SIADH） is a disorder characterized by a series of clinical manifestations，such as excessive free water retained in the body，increased renal excretion of sodium and dilutional hyponatremia.The syndrome results from inappropriate，continued endogenous secretion or enhanced action of the antidiuretic hormone （ADH） by certain pathological conditions，which makes renal collecting duct be more permeable to water.We summarized the diagnosis and treatment of three patients with SIADH in Shengli Oilfield Central Hospital.Furthermore，based on the reviewing of the corresponding studies，we explored the etiology and key points in the diagnosis and management of this disease，in an attempt to present diagnostic approaches as many as possible to reduce the possibilities of missed diagnosis and incorrect diagnosis of SIADH.

Key words: Inappropriate ADH syndrome, Hyponatremia, Case reports, Historical article