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               【编者按】 我国每年约有 54.4 万例心脏性猝死事件发生。在全球范围内,冠心病均是成年人发生心脏性猝死
           的主要病因。相关研究显示,心肌梗死后患者发生心脏性猝死的风险增高 4~10 倍。尽管近年来胸痛中心和区域救治
           体系的建立以及新型改善心血管疾病患者预后药物的成功研发为降低心肌梗死急性期死亡率、长期心血管不良事件发
           生率作出了卓越贡献,但心肌梗死后心脏性猝死在一些具有危险特征的人群中风险仍高,给这些患者和家庭造成了极
           大痛苦,为社会带来了沉重负担。对心肌梗死后患者进行危险分层,准确识别出心脏性猝死的高风险人群,对于实现
           冠心病患者的全程管理和精准防治具有非常重要的意义;然而,现行指南关于心脏性猝死的预防没有覆盖到所有心肌
           梗死后的高风险患者。本文结合最新的证据,对这部分患者的管理建议进行讨论,为指导未来的临床实践、开展后续
           研究提供了方向。


           未被指南涵盖的心肌梗死后猝死
           高风险人群的预测及管理


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           黄宝涛                                                                                查看原文


               【摘要】 目前关于心肌梗死后心脏性猝死的预防主要依赖于左心室射血分数,但是这一单一指标在区分真正的
           猝死高风险人群中存在不足。本文结合近年来出现的新的临床证据,讨论利用左心室射血分数对猝死风险进行分层存
           在的缺陷、心肌梗死后早期对猝死高风险人群进行干预、对射血分数降低的患者重新进行猝死危险分层、识别射血分
           数保留或轻度降低患者中的猝死高风险人群等问题,以及新型临床评分系统、心脏磁共振、无创心电学及侵入性电生
           理检查在猝死预测及管理中的作用,以期为心肌梗死患者的长期精准管理和风险预警提供参考。
               【关键词】 心肌梗死;猝死,心脏;预测;管理;指南
               【中图分类号】 R 542.22 【文献标识码】 A DOI:10.12114/j.issn.1007-9572.2021.01.317
               黄宝涛 . 未被指南涵盖的心肌梗死后猝死高风险人群的预测及管理[J]. 中国全科医学,2022,25(5):515-521.
            [www.chinagp.net]
               HUANG B T. Prediction and management of people at high risk of sudden death after myocardial infarction who are not
           covered by guidelines[J]. Chinese General Practice,2022,25(5):515-521.


           Prediction and Management of People at High Risk of Sudden Death after Myocardial Infarction Who are not Covered
           by Guidelines HUANG Baotao
           Department of Cardiology,West China Hospital,Sichuan University,Chengdu 610041,China
               【Abstract】 The prevention of sudden cardiac death after myocardial infarction in contemporary clinical practice
           primarily relies on the evaluation of left ventricular ejection fraction (LVEF). However,the single measurement is inadequate
           to identify people who are truly at high risk of sudden cardiac death. Based on the new clinical evidence that has been emerged
           in recent years,this review discussed the limitations of risk stratification for sudden death by LVEF,the exploration of early
           intervention in patients with high risk of sudden death after myocardial infarction,the re-stratification of patients with reduced
           LVEF for selecting the candidates who would benefit the most from implantable cardioverter defibrillator treatment,and the
           identification of patients with high risk of sudden death in those with preserved or slightly depressed LVEF. Furthermore,
           the paper reviewed the role of novel clinical scoring systems,cardiac magnetic resonance,noninvasive electrocardiography,
           and invasive electrophysiological testing in the prediction and management of sudden death.This review is expected to provide
           references for the long-term precise management and risk warning of patients with myocardial infarction.
               【Key words】 Myocardial infarction;Death,sudden,cardiac;Forecasting;Management;Guidebooks




               基金项目:四川省科技计划资助项目(2019YFS0351)
               610041 四川省成都市,四川大学华西医院心脏内科
               本文数字出版日期:2022-01-04
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