Upper limb motor dysfunction is a common sequela of stroke that severely impairs patients' ability for self-care, making it a primary focus and key challenge in the rehabilitation process.

To investigate the efficacy of low-frequency repetitive transcranial magnetic stimulation (rTMS) combined with transcutaneous electrical acupoint stimulation (TEAS) in treating upper limb motor impairment after stroke.

Seventy post-stroke patients admitted to Zhejiang Rehabilitation Medical Center from June 2024 to October 2025 were enrolled in this study. They were randomly assigned to three groups using a random number table: control group (n=24), rTMS group (n=23), and a combined group (n=23). The control group received routine rehabilitation training, the rTMS group received low-frequency rTMS alongside with routine training, the combined group received both low-frequency rTMS and TEAS (TEAS administered 10 minutes after rTMS) alongside routine training. All three groups underwent continuous treatment for 8 weeks. The Fugl-Meyer Assessment-upper Extremities (FMA-UE) scores, Modified Barthel Index (MBI) scores, latency and amplitude of transcranial magnetic motor-evoked potentials (TMS-MEP), as well as co-contraction rate (CR) and root mean square (RMS) of the biceps brachii were collected and compared before and after treatment.

After treatment, FMA-UE and MBI scores in all three groups were significantly increased compared with baseline values (P<0.05); Post-hoc pairwise comparisons showed that the rTMS group had higher FMA-UE and MBI scores than the control group, the combined group had higher FMA-UE scores than both the control and rTMS groups and higher MBI scores than the control group (P<0.05). Additionally, TMS-MEP latency and amplitude were improved in all three groups after treatment (P<0.05); Post-hoc pairwise comparisons showed that the combined group had shorter latency than the control group and higher amplitude than both the control and rTMS groups (P<0.05). For all three groups, the CR and RMS of the biceps brachii were significantly improved after treatment (P<0.05); Post-hoc pairwise comparisons showed that, the rTMS group had lower RMS than the control group, while the combined group demonstrated lower CR and RMS than both the control and rTMS groups (P<0.05).

The combination of rTMS and TEAS exerts a favorable therapeutic effect on upper limb motor function recovery in post-stroke patients, as it significantly enhances upper limb motor function, corrects abnormal movement patterns, regulates muscle tone, and improves activities of daily living. Its potential therapeutic mechanism may be related to the improvement of neurological function in the affected area.

上肢运动功能障碍是脑卒中患者常见后遗症之一，严重影响患者生活质量，是脑卒中康复的重点和难点。

探讨低频重复经颅磁刺激（rTMS）联合经皮穴位电刺激（TEAS）对脑卒中患者上肢运动功能恢复的临床干预效果。

选取2024年6月—2025年10月浙江康复医疗中心收治的脑卒中患者70例，采用随机数字表法分为对照组、rTMS组及联合组，其中对照组24例，rTMS组23例，联合组23例。对照组采用常规康复训练方案，rTMS组在常规康复方案基础上辅以低频rTMS，联合组在常规康复方案基础上辅以低频rTMS及TEAS（TEAS在rTMS结束10 min后进行），3组患者均连续治疗8周。收集患者治疗前与治疗后的Fugl-Meyer上肢量表（FMA-UE）评分、改良Barthel指数（MBI）评分、基于经颅磁刺激的运动诱发电位（TMS-MEP）的潜伏期和波幅、表面肌电图（sEMG）的肱二头肌协同收缩率（CR）与均方根值（RMS）进行比较。

3组患者治疗后FMA-UE、MBI评分均较组内治疗前升高（P<0.05）；组间比较结果显示，治疗后rTMS组FMA-UE、MBI评分高于对照组，联合组FMA-UE评分高于对照组与rTMS组、MBI评分高于对照组（P<0.05）。3组患者治疗后TMS-MEP的潜伏期、波幅均较组内治疗前改善（P<0.05）；组间比较结果显示，治疗后联合组TMS-MEP的潜伏期短于对照组，波幅高于对照组和rTMS组（P<0.05）。3组患者治疗后肱二头肌CR、RMS均较组内治疗前降低（P<0.05）；组间比较结果显示，rTMS组RMS低于对照组，联合组CR、RMS低于对照组及rTMS组（P<0.05）。

rTMS与TEAS联合治疗对脑卒中患者上肢运动功能恢复具有较好的治疗效果，可显著改善上肢运动功能、改善上肢异常运动模式、协调上肢张力，从而提高患者日常生活自理能力，其潜在治疗机制可能与改善神经系统功能有关。