
Chinese General Practice ›› 2025, Vol. 28 ›› Issue (22): 2806-2812.DOI: 10.12114/j.issn.1007-9572.2024.0673
Special Issue: 老年人群健康最新文章合辑
• Original Research·Focus on Body Index and Health Relationship • Previous Articles Next Articles
Received:2024-10-15
Revised:2025-05-26
Published:2025-08-05
Online:2025-06-30
Contact:
YANG Jingyuan
通讯作者:
杨敬源
作者简介:作者贡献:
刘美霞提出主要研究目标,负责研究的构思与设计,统计学处理,图、表的绘制与展示,撰写论文;刘美霞、尹金念、吴枚负责文献检索、数据的收集、整理和录入;杨星、周全湘负责调查现场的统筹与协调安排;杨敬源进行论文的修订,负责文章的质量控制与审查,对整个研究进行监督管理,对文章整体负责。
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| 变量 | 低体重组(n=119) | 正常体重组(n=687) | 超重肥胖组(n=385) | 检验统计量值 | P值 |
|---|---|---|---|---|---|
| 年龄( | 73.2±6.5 | 71.4±6.4 | 70.2±6.1 | 11.675a | <0.001 |
| 性别[名(%)] | 12.517c | 0.002 | |||
| 男 | 47(39.6) | 318(46.3) | 136(35.3) | ||
| 女 | 72(60.4) | 369(53.7) | 249(64.7) | ||
| 民族[名(%)] | 5.533c | 0.063 | |||
| 汉族 | 64(53.8) | 352(51.2) | 226(58.7) | ||
| 少数民族 | 55(46.2) | 335(48.8) | 159(41.3) | ||
| 文化程度[名(%)] | 5.460c | 0.243 | |||
| 文盲/半文盲 | 92(77.3) | 522(76.0) | 299(77.7) | ||
| 小学 | 13(10.9) | 109(15.9) | 47(12.2) | ||
| 初中及以上 | 14(11.8) | 56(8.1) | 39(10.1) | ||
| 婚姻状况[名(%)] | 1.632c | 0.442 | |||
| 在婚 | 69(58.0) | 429(62.4) | 248(64.4) | ||
| 非在婚 | 50(42.0) | 258(37.6) | 137(35.6) | ||
| 职业[名(%)] | 1.264c | 0.531 | |||
| 务农 | 110(92.4) | 632(92.0) | 347(90.1) | ||
| 非务农 | 9(7.6) | 55(8.0) | 38(9.9) | ||
| 饮食类型[名(%)] | 2.690c | 0.611 | |||
| 荤素均衡 | 63(52.9) | 371(54.0) | 189(49.1) | ||
| 荤食为主 | 10(8.4) | 66(9.6) | 41(10.6) | ||
| 素食为主 | 46(38.7) | 250(36.4) | 155(40.3) | ||
| 吸烟[名(%)] | 25.401c | <0.001 | |||
| 否 | 90(75.6) | 469(68.3) | 317(82.3) | ||
| 是 | 29(24.4) | 218(31.7) | 68(17.7) | ||
| 饮酒[名(%)] | 10.852c | 0.004 | |||
| 否 | 90(75.6) | 487(70.9) | 308(80.0) | ||
| 是 | 29(24.4) | 200(29.1) | 77(20.0) | ||
| 睡眠质量[名(%)] | 2.077c | 0.354 | |||
| 正常 | 78(65.5) | 478(69.6) | 278(72.2) | ||
| 失眠 | 41(34.5) | 209(30.4) | 107(27.8) | ||
| 血脂异常[名(%)] | 72.472c | <0.001 | |||
| 否 | 115(96.6) | 561(81.7) | 246(63.9) | ||
| 是 | 4(3.4) | 126(18.3) | 139(36.1) | ||
| 糖尿病[名(%)] | 10.213c | 0.006 | |||
| 否 | 116(97.5) | 649(94.5) | 348(90.4) | ||
| 是 | 3(2.5) | 38(5.5) | 37(9.6) | ||
| 心血管疾病[名(%)] | 26.299c | <0.001 | |||
| 否 | 56(47.1) | 317(46.1) | 118(30.6) | ||
| 是 | 63(52.9) | 370(53.9) | 267(69.4) | ||
| MMSE[M(P25,P75),分] | 21.0(16.0,24.0) | 21.0(17.0,25.0) | 22.0(18.0,26.0) | 7.830b | 0.020 |
| BMI( | 17.2±1.0 | 21.2±1.5 | 26.6±2.5 | 1 952.567a | <0.001 |
| TyG[M(P25,P75)] | 8.25(8.03,8.47) | 8.38(8.06,8.73) | 8.85(8.51,9.25) | 194.334b | <0.001 |
| FBG[M(P25,P75),mmol/L] | 4.50(4.18,4.92) | 4.60(4.27,5.02) | 4.84(4.46,5.38) | 45.473b | <0.001 |
| TG[M(P25,P75),mmol/L] | 1.04(0.84,1.25) | 1.17(0.86,1.63) | 1.81(1.29,2.48) | 179.696b | <0.001 |
| TC[M(P25,P75),mmol/L] | 4.61(3.99,5.10) | 4.70(4.15,5.36) | 5.10(4.48,5.70) | 49.737b | <0.001 |
| LDL-C[M(P25,P75),mmol/L] | 2.04(1.63,2.40) | 2.22(1.84,2.71) | 2.54(2.18,3.01) | 84.588b | <0.001 |
| HDL-C[M(P25,P75),mmol/L] | 1.60(1.41,1.90) | 1.54(1.37,1.76) | 1.44(1.29,1.62) | 43.022b | <0.001 |
Table 1 Comparison of demographic characteristics of BMI subgroups in rural elderly people in Guizhou Province
| 变量 | 低体重组(n=119) | 正常体重组(n=687) | 超重肥胖组(n=385) | 检验统计量值 | P值 |
|---|---|---|---|---|---|
| 年龄( | 73.2±6.5 | 71.4±6.4 | 70.2±6.1 | 11.675a | <0.001 |
| 性别[名(%)] | 12.517c | 0.002 | |||
| 男 | 47(39.6) | 318(46.3) | 136(35.3) | ||
| 女 | 72(60.4) | 369(53.7) | 249(64.7) | ||
| 民族[名(%)] | 5.533c | 0.063 | |||
| 汉族 | 64(53.8) | 352(51.2) | 226(58.7) | ||
| 少数民族 | 55(46.2) | 335(48.8) | 159(41.3) | ||
| 文化程度[名(%)] | 5.460c | 0.243 | |||
| 文盲/半文盲 | 92(77.3) | 522(76.0) | 299(77.7) | ||
| 小学 | 13(10.9) | 109(15.9) | 47(12.2) | ||
| 初中及以上 | 14(11.8) | 56(8.1) | 39(10.1) | ||
| 婚姻状况[名(%)] | 1.632c | 0.442 | |||
| 在婚 | 69(58.0) | 429(62.4) | 248(64.4) | ||
| 非在婚 | 50(42.0) | 258(37.6) | 137(35.6) | ||
| 职业[名(%)] | 1.264c | 0.531 | |||
| 务农 | 110(92.4) | 632(92.0) | 347(90.1) | ||
| 非务农 | 9(7.6) | 55(8.0) | 38(9.9) | ||
| 饮食类型[名(%)] | 2.690c | 0.611 | |||
| 荤素均衡 | 63(52.9) | 371(54.0) | 189(49.1) | ||
| 荤食为主 | 10(8.4) | 66(9.6) | 41(10.6) | ||
| 素食为主 | 46(38.7) | 250(36.4) | 155(40.3) | ||
| 吸烟[名(%)] | 25.401c | <0.001 | |||
| 否 | 90(75.6) | 469(68.3) | 317(82.3) | ||
| 是 | 29(24.4) | 218(31.7) | 68(17.7) | ||
| 饮酒[名(%)] | 10.852c | 0.004 | |||
| 否 | 90(75.6) | 487(70.9) | 308(80.0) | ||
| 是 | 29(24.4) | 200(29.1) | 77(20.0) | ||
| 睡眠质量[名(%)] | 2.077c | 0.354 | |||
| 正常 | 78(65.5) | 478(69.6) | 278(72.2) | ||
| 失眠 | 41(34.5) | 209(30.4) | 107(27.8) | ||
| 血脂异常[名(%)] | 72.472c | <0.001 | |||
| 否 | 115(96.6) | 561(81.7) | 246(63.9) | ||
| 是 | 4(3.4) | 126(18.3) | 139(36.1) | ||
| 糖尿病[名(%)] | 10.213c | 0.006 | |||
| 否 | 116(97.5) | 649(94.5) | 348(90.4) | ||
| 是 | 3(2.5) | 38(5.5) | 37(9.6) | ||
| 心血管疾病[名(%)] | 26.299c | <0.001 | |||
| 否 | 56(47.1) | 317(46.1) | 118(30.6) | ||
| 是 | 63(52.9) | 370(53.9) | 267(69.4) | ||
| MMSE[M(P25,P75),分] | 21.0(16.0,24.0) | 21.0(17.0,25.0) | 22.0(18.0,26.0) | 7.830b | 0.020 |
| BMI( | 17.2±1.0 | 21.2±1.5 | 26.6±2.5 | 1 952.567a | <0.001 |
| TyG[M(P25,P75)] | 8.25(8.03,8.47) | 8.38(8.06,8.73) | 8.85(8.51,9.25) | 194.334b | <0.001 |
| FBG[M(P25,P75),mmol/L] | 4.50(4.18,4.92) | 4.60(4.27,5.02) | 4.84(4.46,5.38) | 45.473b | <0.001 |
| TG[M(P25,P75),mmol/L] | 1.04(0.84,1.25) | 1.17(0.86,1.63) | 1.81(1.29,2.48) | 179.696b | <0.001 |
| TC[M(P25,P75),mmol/L] | 4.61(3.99,5.10) | 4.70(4.15,5.36) | 5.10(4.48,5.70) | 49.737b | <0.001 |
| LDL-C[M(P25,P75),mmol/L] | 2.04(1.63,2.40) | 2.22(1.84,2.71) | 2.54(2.18,3.01) | 84.588b | <0.001 |
| HDL-C[M(P25,P75),mmol/L] | 1.60(1.41,1.90) | 1.54(1.37,1.76) | 1.44(1.29,1.62) | 43.022b | <0.001 |
| 变量 | 模型1 | 模型2 | ||
|---|---|---|---|---|
| β(95%CI) | P值 | β(95%CI) | P值 | |
| BMI分组 | ||||
| 18.5~23.9 kg/m2 | 1.000 | 1.000 | ||
| <18.5 kg/m2 | -0.238(-0.432~-0.044) | 0.016 | -0.119(-0.283~0.046) | 0.158 |
| ≥24.0 kg/m2 | 0.099(-0.026~0.223) | 0.119 | 0.145(0.036~0.255) | 0.009 |
| TyG水平每增加1个标准差 | -0.020(-0.077~0.037) | 0.493 | -0.030(-0.101~0.042) | 0.414 |
| 交互作用 | ||||
| TyG×中BMI | 1.000 | 1.000 | ||
| TyG×低BMI | -0.515(-0.809~-0.222) | <0.001 | -0.351(-0.601~-0.102) | 0.006 |
| TyG×高BMI | 0.040(-0.088~0.169) | 0.540 | -0.035(-0.144~0.075) | 0.537 |
Table 2 Multiple linear regression and interaction analysis of TyG,BMI and cognitive function in older adults
| 变量 | 模型1 | 模型2 | ||
|---|---|---|---|---|
| β(95%CI) | P值 | β(95%CI) | P值 | |
| BMI分组 | ||||
| 18.5~23.9 kg/m2 | 1.000 | 1.000 | ||
| <18.5 kg/m2 | -0.238(-0.432~-0.044) | 0.016 | -0.119(-0.283~0.046) | 0.158 |
| ≥24.0 kg/m2 | 0.099(-0.026~0.223) | 0.119 | 0.145(0.036~0.255) | 0.009 |
| TyG水平每增加1个标准差 | -0.020(-0.077~0.037) | 0.493 | -0.030(-0.101~0.042) | 0.414 |
| 交互作用 | ||||
| TyG×中BMI | 1.000 | 1.000 | ||
| TyG×低BMI | -0.515(-0.809~-0.222) | <0.001 | -0.351(-0.601~-0.102) | 0.006 |
| TyG×高BMI | 0.040(-0.088~0.169) | 0.540 | -0.035(-0.144~0.075) | 0.537 |
| 变量 | 低体重组 | |||
|---|---|---|---|---|
| β1(95%CI) | P值 | β2(95%CI) | P值 | |
| TyG指数 | ||||
| Q1 | 1.000 | 1.000 | ||
| Q2 | -0.442(-0.936~0.051) | 0.079 | -0.247(-0.655~0.161) | 0.232 |
| Q3 | -0.465(-0.950~0.021) | 0.061 | -0.453(-0.862~-0.043) | 0.031 |
| Q4 | -0.926(-1.420~-0.432) | <0.001 | -0.503(-0.957~-0.050) | 0.030 |
| TyG水平每增加1个标准差 | -0.318(-0.492~-0.145) | <0.001 | -0.251(-0.421~-0.081) | 0.004 |
| 变量 | 正常体重组 | |||
| β1(95%CI) | P值 | β2(95%CI) | P值 | |
| TyG指数 | ||||
| Q1 | 1.000 | 1.000 | ||
| Q2 | -0.143(-0.355~0.069) | 0.185 | -0.023(-0.203~0.157) | 0.800 |
| Q3 | -0.060(-0.272~0.152) | 0.576 | 0.129(-0.055~0.313) | 0.169 |
| Q4 | -0.138(-0.351~0.074) | 0.201 | 0.012(-0.207~0.231) | 0.914 |
| TyG水平每增加1个标准差 | -0.047(-0.122~0.028) | 0.223 | 0.001(-0.087~0.089) | 0.979 |
| 变量 | 超重肥胖组 | |||
| β1(95%CI) | P值 | β2(95%CI) | P值 | |
| TyG指数 | ||||
| Q1 | 1.000 | 1.000 | ||
| Q2 | -0.046(-0.330~0.238) | 0.751 | -0.006(-0.255~0.242) | 0.962 |
| Q3 | 0.010(-0.274~0.294) | 0.943 | 0.145(-0.124~0.414) | 0.290 |
| Q4 | 0.066(-0.218~0.350) | 0.646 | 0.138(-0.204~0.480) | 0.427 |
| TyG水平每增加1个标准差 | -0.009(-0.110~0.091) | 0.858 | -0.018(-0.147~0.110) | 0.779 |
Table 3 Multiple linear regression analysis for the association of TyG with cognitive function according to body mass index
| 变量 | 低体重组 | |||
|---|---|---|---|---|
| β1(95%CI) | P值 | β2(95%CI) | P值 | |
| TyG指数 | ||||
| Q1 | 1.000 | 1.000 | ||
| Q2 | -0.442(-0.936~0.051) | 0.079 | -0.247(-0.655~0.161) | 0.232 |
| Q3 | -0.465(-0.950~0.021) | 0.061 | -0.453(-0.862~-0.043) | 0.031 |
| Q4 | -0.926(-1.420~-0.432) | <0.001 | -0.503(-0.957~-0.050) | 0.030 |
| TyG水平每增加1个标准差 | -0.318(-0.492~-0.145) | <0.001 | -0.251(-0.421~-0.081) | 0.004 |
| 变量 | 正常体重组 | |||
| β1(95%CI) | P值 | β2(95%CI) | P值 | |
| TyG指数 | ||||
| Q1 | 1.000 | 1.000 | ||
| Q2 | -0.143(-0.355~0.069) | 0.185 | -0.023(-0.203~0.157) | 0.800 |
| Q3 | -0.060(-0.272~0.152) | 0.576 | 0.129(-0.055~0.313) | 0.169 |
| Q4 | -0.138(-0.351~0.074) | 0.201 | 0.012(-0.207~0.231) | 0.914 |
| TyG水平每增加1个标准差 | -0.047(-0.122~0.028) | 0.223 | 0.001(-0.087~0.089) | 0.979 |
| 变量 | 超重肥胖组 | |||
| β1(95%CI) | P值 | β2(95%CI) | P值 | |
| TyG指数 | ||||
| Q1 | 1.000 | 1.000 | ||
| Q2 | -0.046(-0.330~0.238) | 0.751 | -0.006(-0.255~0.242) | 0.962 |
| Q3 | 0.010(-0.274~0.294) | 0.943 | 0.145(-0.124~0.414) | 0.290 |
| Q4 | 0.066(-0.218~0.350) | 0.646 | 0.138(-0.204~0.480) | 0.427 |
| TyG水平每增加1个标准差 | -0.009(-0.110~0.091) | 0.858 | -0.018(-0.147~0.110) | 0.779 |
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