Advances in the Study of Sleep-related Subjective Cognitive Decline

doi:10.12114/j.issn.1007-9572.2024.0111

Chinese General Practice ›› 2025, Vol. 28 ›› Issue (11): 1403-1410.DOI: 10.12114/j.issn.1007-9572.2024.0111

Special Issue: 睡眠研究最新文章合辑；睡眠问题专题研究

• Review & Perspectives • Previous Articles Next Articles

Advances in the Study of Sleep-related Subjective Cognitive Decline

1. Department of Sleep Medicine, the People's Hospital of Guangxi Zhuang Autonomous Region/Guangxi Academy of Medical Sciences, Nanning 530000, China
2. Guangxi Research Center for Sleep Medicine in Clinical Medical Sciences, Nanning 530000, China
3. Guangxi Sleep Respiratory Disease Diagnosis and Treatment Center, Nanning 530000, China
4. Guangxi Medical University, Nanning 530021, China
5. Graduate School, Guilin Medical University, Guilin 541100, China

Received:2024-04-10 Revised:2024-06-10 Published:2025-04-15 Online:2025-02-06
Contact: ZHAO Mingming

睡眠相关主观认知下降的研究新进展

1．530000　广西壮族自治区南宁市，广西壮族自治区人民医院　广西医学科学院睡眠医学科
2．530000　广西壮族自治区南宁市，广西睡眠医学临床医学研究中心
3．530000　广西壮族自治区南宁市，广西睡眠呼吸疾病诊疗中心
4．530021　广西壮族自治区南宁市，广西医科大学
5．541100　广西壮族自治区桂林市，桂林医学院研究生院

通讯作者: 赵明明
作者简介:
作者贡献：
文依宁负责设计框架、搜集和整理研究资料并撰写论文；黄惠嫦负责论文修订和文献的整理；赵明明负责论文审校、文章的质量控制及监督管理，对文章整体负责。
基金资助:
国家自然科学基金资助项目(82260021); 广西自然科学基金资助项目(2022GXNSFBA035655); 广西哲学社会科学规划研究课题(22FGL042); 中国博士后基金面上项目(2020M670207)

Abstract

Abstract:

Subjective cognitive decline (SCD) usually predicts the risk of future cognitive decline, and sleep disturbances are very common in patients with SCD and often precede detectable cognitive changes. Although there is a lack of clarity regarding the relationship between sleep and SCD and the underlying mechanisms of sleep-related cognitive deterioration, studies in recent years have shown a strong link between sleep and cognitive decline. Cognitive decline may be triggered by either sleep deprivation or decreased sleep quality. Therefore, the aim of this review is to provide a comprehensive overview of the research progress on sleep and subjective cognitive decline, and to explore in depth the mechanism of their interaction, with a view to providing new ideas and methods for preventing and delaying cognitive decline, and providing useful references for research and practice in related fields.

Key words: Subjective cognitive decline, Sleep, Sleep disorders, Sleep fragmentation, Slow wave sleep, Alzheimer's disease

摘要：

主观认知下降（SCD）通常预示着未来认知功能下降的风险，而睡眠障碍在SCD患者中较常见，并且通常在可检测到的认知变化之前就已表现出来。虽然目前关于睡眠与SCD之间关系以及睡眠相关认知功能退化的基本机制尚不明确，但近年来的研究表明，睡眠与认知功能下降之间存在紧密的联系。睡眠不足或睡眠质量的下降均可能引发认知功能的衰退。因此，本文旨在全面综述睡眠与SCD的研究进展，深入探讨二者之间的相互作用机制，以期为预防和延缓认知下降提供新的思路和方法，为相关领域的研究和实践提供有益的参考。

关键词: 主观认知下降, 睡眠, 睡眠障碍, 睡眠片段化, 慢波睡眠, 阿尔茨海默病

CLC Number:

R 741

WEN Yining,HUANG Huichang,ZHAO Mingming. Advances in the Study of Sleep-related Subjective Cognitive Decline[J]. Chinese General Practice, 2025, 28(11): 1403-1410. DOI: 10.12114/j.issn.1007-9572.2024.0111.
文依宁,黄惠嫦,赵明明. 睡眠相关主观认知下降的研究新进展[J]. 中国全科医学, 2025, 28(11): 1403-1410. DOI: 10.12114/j.issn.1007-9572.2024.0111.

References 82

[1]	JESSEN F，WIESE B，BACHMANN C，et al. Prediction of dementia by subjective memory impairment：effects of severity and temporal association with cognitive impairment[J]. Arch Gen Psychiatry，2010，67（4）：414-422. DOI：10.1001/archgenpsychiatry.2010.30.
[2]	JESSEN F，AMARIGLIO R E，VAN BOXTEL M，et al. A conceptual framework for research on subjective cognitive decline in preclinical Alzheimer's disease[J]. Alzheimers Dement，2014，10（6）：844-852. DOI：10.1016/j.jalz.2014.01.001.
[3]	PETERSEN R C，WISTE H J，WEIGAND S D，et al. NIA-AA Alzheimer's disease framework：clinical characterization of stages[J]. Ann Neurol，2021，89（6）：1145-1156. DOI：10.1002/ana.26071.
[4]	杨挺，吴劲松，韩梦宇，等. 阿尔茨海默病临床前期不同认知领域的变化特征研究[J]. 中国全科医学，2021，24（12）：1470-1475. DOI：10.12114/j.issn.1007-9572.2020.00.641.
[5]	JESSEN F，AMARIGLIO R E，BUCKLEY R F，et al. The characterisation of subjective cognitive decline[J]. Lancet Neurol，2020，19（3）：271-278. DOI：10.1016/S1474-4422(19)30368-0.
[6]	XU W，TAN C C，ZOU J J，et al. Sleep problems and risk of all-cause cognitive decline or dementia：an updated systematic review and meta-analysis[J]. J Neurol Neurosurg Psychiatry，2020，91（3）：236-244. DOI：10.1136/jnnp-2019-321896.
[7]	RÖHR S，PABST A，RIEDEL-HELLER S G，et al. Estimating prevalence of subjective cognitive decline in and across international cohort studies of aging：a COSMIC study[J]. Alzheimers Res Ther，2020，12（1）：167. DOI：10.1186/s13195-020-00734-y.
[8]	熊风，赖玉清，涂嘉欣，等. 中国老年人群睡眠障碍流行特征的Meta分析[J]. 中国循证医学杂志，2019，19（4）：398-403. DOI：10.7507/1672-2531.201808151.
[9]	韩婷婷，崔小川，韩芳. 全科医学与睡眠医学如何协同发展[J]. 中国全科医学，2023，26（20）：2447-2451. DOI：10.12114/j.issn.1007-9572.2022.0482.
[10]	SULAMAN B A，WANG S，TYAN J，et al. Neuro-orchestration of sleep and wakefulness[J]. Nat Neurosci，2023，26（2）：196-212. DOI：10.1038/s41593-022-01236-w.
[11]	KLINZING J G，NIETHARD N，BORN J. Mechanisms of systems memory consolidation during sleep[J]. Nat Neurosci，2019，22（10）：1598-1610. DOI：10.1038/s41593-019-0467-3.
[12]	TSAPANOU A，VLACHOS G S，COSENTINO S，et al. Sleep and subjective cognitive decline in cognitively healthy elderly：results from two cohorts[J]. J Sleep Res，2019，28（5）：e12759. DOI：10.1111/jsr.12759.
[13]	WANG X Q，HUANG W J，SU L，et al. Neuroimaging advances regarding subjective cognitive decline in preclinical Alzheimer's disease[J]. Mol Neurodegener，2020，15（1）：55. DOI：10.1186/s13024-020-00395-3.
[14]	EXALTO L G，HENDRIKSEN H M A，BARKHOF F，et al. Subjective cognitive decline and self-reported sleep problems：the SCIENCe project[J]. Alzheimers Dement，2022，14（1）：e12287. DOI：10.1002/dad2.12287.
[15]	CHEN G Q，YANG K，DU W Y，et al. Clinical characteristics in subjective cognitive decline with and without worry：baseline investigation of the SILCODE study[J]. J Alzheimers Dis，2019，72（2）：443-454. DOI：10.3233/JAD-190501.
[16]	MANOUSAKIS J E，NICHOLAS C，SCOVELLE A J，et al. Associations between sleep and verbal memory in subjective cognitive decline：a role for semantic clustering[J]. Neurobiol Learn Mem，2019，166：107086. DOI：10.1016/j.nlm.2019.107086.
[17]	BUBBICO G，DI IORIO A，LAURIOLA M，et al. Subjective cognitive decline and nighttime sleep alterations，a longitudinal analysis[J]. Front Aging Neurosci，2019，11：142. DOI：10.3389/fnagi.2019.00142.
[18]	MANOUSAKIS J E，SCOVELLE A J，RAJARATNAM S M W，et al. Advanced circadian timing and sleep fragmentation differentially impact on memory complaint subtype in subjective cognitive decline[J]. J Alzheimers Dis，2018，66（2）：565-577. DOI：10.3233/JAD-180612.
[19]	KIM W H，KIM J H，KIM B S，et al. The role of depression in the insomnia of people with subjective memory impairment，mild cognitive impairment，and dementia in a community sample of elderly individuals in South Korea[J]. Int Psychogeriatr，2017，29（4）：653-661. DOI：10.1017/S1041610216002076.
[20]	SMITH L，OH H，JACOB L，et al. Sleep problems and subjective cognitive complaints among middle-aged and older adults in 45 low- and middle-income countries[J]. Aging Clin Exp Res，2022，34（6）：1285-1293. DOI：10.1007/s40520-021-02052-1.
[21]	LENG M M，YIN H R，ZHANG P，et al. Sleep quality and health-related quality of life in older people with subjective cognitive decline，mild cognitive impairment，and alzheimer disease[J]. J Nerv Ment Dis，2020，208（5）：387-396. DOI：10.1097/NMD.0000000000001137.
[22]	TARDY M，GONTHIER R，BARTHELEMY J C，et al. Subjective sleep and cognitive complaints in 65 year old subjects：a significant association. The PROOF cohort[J]. J Nutr Health Aging，2015，19（4）：424-430. DOI：10.1007/s12603-014-0547-8.
[23]	LIN L H，XU W Q，WANG S B，et al. U-shaped association between sleep duration and subjective cognitive complaints in Chinese elderly：a cross-sectional study[J]. BMC Psychiatry，2022，22（1）：147. DOI：10.1186/s12888-022-03738-0.
[24]	LEE J E，JU Y J，CHUN K H，et al. The frequency of sleep medication use and the risk of subjective cognitive decline（SCD）or SCD with functional difficulties in elderly individuals without dementia[J]. J Gerontol A Biol Sci Med Sci，2020，75（9）：1693-1698. DOI：10.1093/gerona/glz269.
[25]	ZHAO J L，CROSS N，YAO C W，et al. Insomnia disorder increases the risk of subjective memory decline in middle-aged and older adults：a longitudinal analysis of the Canadian Longitudinal Study on Aging[J]. Sleep，2022，45（11）：zsac176. DOI：10.1093/sleep/zsac176.
[26]	AKINCI M，SÁNCHEZ-BENAVIDES G，BRUGULAT-SERRAT A，et al. Subjective cognitive decline and anxious/depressive symptoms during the COVID-19 pandemic：what is the role of stress perception，stress resilience，and β-amyloid?[J]. Alzheimers Res Ther，2022，14（1）：126. DOI：10.1186/s13195-022-01068-7.
[27]	JIANG H X，XIE X，XU Y，et al. Older adults' subjective cognitive decline correlated with subjective but not objective sleep：a mediator role of depression[J]. Int J Aging Hum Dev，2022，95（1）：42-56. DOI：10.1177/00914150211024186.
[28]	宋银华，刘玉双，杨青，等. 老年人主观认知下降与慢性病共病的相关性分析[J]. 中国全科医学，2023，26（10）：1241-1249. DOI：10.12114/j.issn.1007-9572.2022.0800.
[29]	PODLESEK A，KOMIDAR L，KAVCIC V. The relationship between perceived stress and subjective cognitive decline during the COVID-19 epidemic[J]. Front Psychol，2021，12：647971. DOI：10.3389/fpsyg.2021.647971.
[30]	COSTA A N，MCCRAE C S，COWAN N，et al. Paradoxical relationship between subjective and objective cognition：the role of sleep[J]. J Clin Sleep Med，2022，18（8）：2009-2022. DOI：10.5664/jcsm.10070.
[31]	LAURIOLA M，ESPOSITO R，DE ZAMBOTTI M，et al. O₂-04-04：disrupted sleep in subjective cognitive decline[J]. Alzheimers Dement，2016，12（7S_Part_4）. DOI：10.1016/j.jalz.2016.06.414.
[32]	HU Q，SONG Y H，WANG S B，et al. Association of subjective cognitive complaints with poor sleep quality：a cross-sectional study among Chinese elderly[J]. Int J Geriatr Psychiatry，2023，38（6）：e5956. DOI：10.1002/gps.5956.
[33]	LENG Y，KNUTSON K，CARNETHON M R，et al. Association between sleep quantity and quality in early adulthood with cognitive function in midlife[J]. Neurology，2024，102（2）：e208056. DOI：10.1212/WNL.0000000000208056.
[34]	RATTANABANNAKIT C，KUENDEE S，TUNGWACHARAPONG P，et al. Subjective cognitive complaints and objective cognitive impairment in patients suspected of obstructive sleep apnea who underwent polysomnography[J]. Int J Geriatr Psychiatry，2024，39（1）：e6055. DOI：10.1002/gps.6055.
[35]	覃丽霞，钟清清，陆怡安，等. 老年阻塞性睡眠呼吸暂停合并认知功能障碍患者睡眠及脑功能状态特点[J]. 中国临床新医学，2024，17（1）：12-18. DOI：10.3969/j.issn.1674-3806.2024.01.03.
[36]	LINSSEN B，BERGMAN E，KLARENBEEK P，et al. Prevalence of obstructive sleep apnea at an outpatient memory clinic[J]. Health Sci Rep，2021，4（1）：e228. DOI：10.1002/hsr2.228.
[37]	GAGNON K，BARIL A A，MONTPLAISIR J，et al. Disconnection between self-reported and objective cognitive impairment in obstructive sleep apnea[J]. J Clin Sleep Med，2019，15（3）：409-415. DOI：10.5664/jcsm.7664.
[38]	ANDRÉ C，TOMADESSO C，DE FLORES R，et al. Brain and cognitive correlates of sleep fragmentation in elderly subjects with and without cognitive deficits[J]. Alzheimers Dement，2019，11：142-150. DOI：10.1016/j.dadm.2018.12.009.
[39]	LAM A K F，CARRICK J，KAO C H，et al. EEG slowing during REM sleep in older adults with subjective cognitive impairment and mild cognitive impairment[J]. Sleep，2024：zsae051. DOI：10.1093/sleep/zsae051.
[40]	FLORES-TORRES M H，BJORNEVIK K，HUNG A Y，et al. Subjective cognitive decline in women with features suggestive of prodromal Parkinson's disease[J]. Mov Disord，2023，38（8）：1473-1482. DOI：10.1002/mds.29503.
[41]	HU M T. REM sleep behavior disorder（RBD）[J]. Neurobiol Dis，2020，143：104996. DOI：10.1016/j.nbd.2020.104996.
[42]	LANE J M，QIAN J Y，MIGNOT E，et al. Genetics of circadian rhythms and sleep in human health and disease[J]. Nat Rev Genet，2023，24（1）：4-20. DOI：10.1038/s41576-022-00519-z.
[43]	JOZWIAK N，POSTUMA R B，MONTPLAISIR J，et al. REM sleep behavior disorder and cognitive impairment in Parkinson's disease[J]. Sleep，2017，40（8）：zsx101. DOI：10.1093/sleep/zsx101.
[44]	CHAVDA V，CHAURASIA B，UMANA G E，et al. Narcolepsy-a neuropathological obscure sleep disorder：a narrative review of current literature[J]. Brain Sci，2022，12（11）：1473. DOI：10.3390/brainsci12111473.
[45]	BHALSING K，SURESH K，MUTHANE U B，et al. Prevalence and profile of Restless Legs Syndrome in Parkinson's disease and other neurodegenerative disorders：a case-control study[J]. Parkinsonism Relat Disord，2013，19（4）：426-430. DOI：10.1016/j.parkreldis.2012.12.005.
[46]	FERESHTEHNEJAD S M，RAHMANI A，SHAFIEESABET M，et al. Prevalence and associated comorbidities of restless legs syndrome（RLS）：data from a large population-based door-to-door survey on 19176 adults in Tehran，Iran[J]. PLoS One，2017，12（2）：e0172593. DOI：10.1371/journal.pone.0172593.
[47]	MEDRANO-MARTÍNEZ P，GÓMEZ-SACRISTAN Á，PERAITA-ADRADOS R. Is memory impaired in narcolepsy type 1?[J]. J Sleep Res，2022，31（5）：e13593. DOI：10.1111/jsr.13593.
[48]	BESSI V，GIACOMUCCI G，MAZZEO S，et al. PER2 C111G polymorphism，cognitive reserve and cognition in subjective cognitive decline and mild cognitive impairment：a 10-year follow-up study[J]. Eur J Neurol，2021，28（1）：56-65. DOI：10.1111/ene.14518.
[49]	LAFRENIÈRE A，LINA J M，HERNANDEZ J，et al. Sleep slow waves' negative-to-positive-phase transition：a marker of cognitive and apneic status in aging[J]. Sleep，2023，46（1）：zsac246. DOI：10.1093/sleep/zsac246.
[50]	TONONI G，CIRELLI C. Sleep function and synaptic homeostasis[J]. Sleep Med Rev，2006，10（1）：49-62. DOI：10.1016/j.smrv.2005.05.002.
[51]	ZAVECZ Z，SHAH V D，MURILLO O G，et al. NREM sleep as a novel protective cognitive reserve factor in the face of Alzheimer's disease pathology[J]. BMC Med，2023，21（1）：156. DOI：10.1186/s12916-023-02811-z.
[52]	TAILLARD J，SAGASPE P，BERTHOMIER C，et al. Non-REM sleep characteristics predict early cognitive impairment in an aging population[J]. Front Neurol，2019，10：197. DOI：10.3389/fneur.2019.00197.
[53]	JO K J，HO S，HONG Y J，et al. Relationship between amyloid positivity and sleep characteristics in the elderly with subjective cognitive decline. dement neurocogn disord[J]. 2024，23（1）：22-29. DOI：10.12779/dnd.2024.23.1.22.
[54]	LI M F，SUN Z R，SUN H R，et al. Paroxysmal slow wave events are associated with cognitive impairment in patients with obstructive sleep apnea[J]. Alzheimers Res Ther，2022，14（1）：200. DOI：10.1186/s13195-022-01153-x.
[55]	朱麒霖，韩菲，王婧，等. 睡眠纺锤波密度对阻塞性睡眠呼吸暂停低通气综合征患者记忆功能的影响[J]. 中华结核和呼吸杂志，2023，46（5）：466-473. DOI：10.3760/cma.j.cn112147-20220924-00779.
[56]	HOLTH J K，FRITSCHI S K，WANG C，et al. The sleep-wake cycle regulates brain interstitial fluid tau in mice and CSF tau in humans[J]. Science，2019，363（6429）：880-884. DOI：10.1126/science.aav2546.
[57]	BA L，HUANG L F，HE Z Y，et al. Does chronic sleep fragmentation lead to Alzheimer's disease in young wild-type mice?[J]. Front Aging Neurosci，2021，13：759983. DOI：10.3389/fnagi.2021.759983.
[58]	KANESHWARAN K，OLAH M，TASAKI S，et al. Sleep fragmentation，microglial aging，and cognitive impairment in adults with and without Alzheimer's dementia[J]. Sci Adv，2019，5（12）：eaax7331. DOI：10.1126/sciadv.aax7331.
[59]	SANG D，LIN K T，YANG Y N，et al. Prolonged sleep deprivation induces a cytokine-storm-like syndrome in mammals[J]. Cell，2023，186（25）：5500-5516.e21. DOI：10.1016/j.cell.2023.10.025.
[60]	LI N，TAN S W，WANG Y，et al. Akkermansia muciniphila supplementation prevents cognitive impairment in sleep-deprived mice by modulating microglial engulfment of synapses[J]. Gut Microbes，2023，15（2）：2252764. DOI：10.1080/19490976.2023.2252764.
[61]	VACCARO A，KAPLAN DOR Y，NAMBARA K，et al. Sleep loss can cause death through accumulation of reactive oxygen species in the gut[J]. Cell，2020，181（6）：1307-1328.e15. DOI：10.1016/j.cell.2020.04.049.
[62]	IRWIN M R. Sleep and inflammation：partners in sickness and in health[J]. Nat Rev Immunol，2019，19（11）：702-715. DOI：10.1038/s41577-019-0190-z.
[63]	ZHAO B Y，LIU P，WEI M，et al. Chronic sleep restriction induces aβ accumulation by disrupting the balance of aβ production and clearance in rats[J]. Neurochem Res，2019，44（4）：859-873. DOI：10.1007/s11064-019-02719-2.
[64]	KANG J E，LIM M M，BATEMAN R J，et al. Amyloid-beta dynamics are regulated by orexin and the sleep-wake cycle[J]. Science，2009，326（5955）：1005-1007. DOI：10.1126/science.1180962.
[65]	HABLITZ L M，PLÁ V，GIANNETTO M，et al. Circadian control of brain glymphatic and lymphatic fluid flow[J]. Nat Commun，2020，11（1）：4411. DOI：10.1038/s41467-020-18115-2.
[66]	XIE L L，KANG H Y，XU Q W，et al. Sleep drives metabolite clearance from the adult brain[J]. Science，2013，342（6156）：373-377. DOI：10.1126/science.1241224.
[67]	ZHANG J，ZHU Y，ZHAN G X，et al. Extended wakefulness：compromised metabolics in and degeneration of locus ceruleus neurons[J]. J Neurosci，2014，34（12）：4418-4431. DOI：10.1523/JNEUROSCI.5025-12.2014.
[68]	YUAN R K，LOPEZ M R，RAMOS-ALVAREZ M M，et al. Differential effect of sleep deprivation on place cell representations，sleep architecture，and memory in young and old mice[J]. Cell Rep，2021，35（11）：109234. DOI：10.1016/j.celrep.2021.109234.
[69]	中华医学会神经病学分会睡眠障碍学组，中国医师协会神经内科分会睡眠障碍专业委员会，中国睡眠研究会睡眠障碍专业委员会. 认知功能损害患者睡眠障碍评估和管理的专家共识[J]. 中华医学杂志，2018，98（33）：2619-2627. DOI：10.3760/cma.j.issn.0376-2491.2018.33.002.
[70]	韩芳. 健康中国视域下睡眠呼吸障碍性疾病的诊疗与管理策略[J]. 中国临床新医学，2024，17（1）：1-5. DOI：10.3969/j.issn.1674-3806.2024.01.01.
[71]	MARTIN J L，SONG Y，HUGHES J，et al. A four-session sleep intervention program improves sleep for older adult day health care participants：results of a randomized controlled trial[J]. Sleep，2017，40（8）：zsx079. DOI：10.1093/sleep/zsx079.
[72]	陈军君，李凡，赵文瑞，等. 远程失眠认知行为治疗慢性失眠障碍的疗效研究[J]. 中国临床新医学，2024，17（1）：30-34. DOI：10.3969/j.issn.1674-3806.2024.01.06.
[73]	INNES K E，SELFE T K，BRUNDAGE K，et al. Effects of meditation and music-listening on blood biomarkers of cellular aging and Alzheimer's disease in adults with subjective cognitive decline：an exploratory randomized clinical trial[J]. J Alzheimers Dis，2018，66（3）：947-970. DOI：10.3233/JAD-180164.
[74]	ZHANG Y J，GRUBER R. Can slow-wave sleep enhancement improve memory? A review of current approaches and cognitive outcomes[J]. Yale J Biol Med，2019，92（1）：63-80.
[75]	LANZA G，FISICARO F，CANTONE M，et al. Repetitive transcranial magnetic stimulation in primary sleep disorders[J]. Sleep Med Rev，2023，67：101735. DOI：10.1016/j.smrv.2022.101735.
[76]	JUDA M，LIU-AMBROSE T，FELDMAN F，et al. Light in the senior home：effects of dynamic and individual light exposure on sleep，cognition，and well-being[J]. Clocks Sleep，2020，2（4）：557-576. DOI：10.3390/clockssleep2040040.
[77]	ZHAO X，DU W Y，JIANG J H，et al. Brain photobiomodulation improves sleep quality in subjective cognitive decline：a randomized，sham-controlled study[J]. J Alzheimers Dis，2022，87（4）：1581-1589. DOI：10.3233/JAD-215715.
[78]	TROUSSIÈRE A C，CHARLEY C M，SALLERON J，et al. Treatment of sleep apnoea syndrome decreases cognitive decline in patients with Alzheimer's disease[J]. J Neurol Neurosurg Psychiatry，2014，85（12）：1405-1408. DOI：10.1136/jnnp-2013-307544.
[79]	CHAPPEL-FARLEY M G，MANDER B A，NEIKRUG A B，et al. Symptoms of obstructive sleep apnea are associated with less frequent exercise and worse subjective cognitive function across adulthood[J]. Sleep，2022，45（3）：zsab240. DOI：10.1093/sleep/zsab240.
[80]	DYER A H，MURPHY C，LAWLOR B，et al. Cognitive outcomes of long-term benzodiazepine and related drug（BDZR）use in people living with mild to moderate Alzheimer's disease：results from NILVAD[J]. J Am Med Dir Assoc，2020，21（2）：194-200. DOI：10.1016/j.jamda.2019.08.006.
[81]	HERRING W J，CONNOR K M，IVGY-MAY N，et al. Suvorexant in patients with insomnia：results from two 3-month randomized controlled clinical trials[J]. Biol Psychiatry，2016，79（2）：136-148. DOI：10.1016/j.biopsych.2014.10.003.
[82]	JEAN-LOUIS G，VON GIZYCKI H，ZIZI F. Melatonin effects on sleep，mood，and cognition in elderly with mild cognitive impairment[J]. J Pineal Res，1998，25（3）：177-183. DOI：10.1111/j.1600-079x.1998.tb00557.x.

Advances in the Study of Sleep-related Subjective Cognitive Decline

睡眠相关主观认知下降的研究新进展

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