Chinese General Practice ›› 2023, Vol. 26 ›› Issue (24): 3033-3041.DOI: 10.12114/j.issn.1007-9572.2022.0828
Special Issue: 消化系统疾病最新文章合辑; 脑健康最新研究合辑
• Original Research • Previous Articles Next Articles
Received:
2022-09-05
Revised:
2023-01-14
Published:
2023-08-20
Online:
2022-12-20
Contact:
WANG Xiaodong
通讯作者:
王晓东
作者简介:
基金资助:
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URL: https://www.chinagp.net/EN/10.12114/j.issn.1007-9572.2022.0828
扫描序列 | 3D-T1 BRAVO | BOLD-fMRI |
---|---|---|
重复时间(ms) | 7.7 | 2 000 |
回波时间(ms) | 3.1 | 30 |
翻转角 | 12° | 90° |
视野(mm) | 240×240 | 250×250 |
矩阵 | 256×256 | 64×64 |
层厚(mm) | 1.2 | 3.6 |
层数 | 136 | 35 |
扫描时间(s) | 215 | 360 |
Table 1 Data acquisition parameters of 3D-T1 BRAVO and BOLD-fMRI
扫描序列 | 3D-T1 BRAVO | BOLD-fMRI |
---|---|---|
重复时间(ms) | 7.7 | 2 000 |
回波时间(ms) | 3.1 | 30 |
翻转角 | 12° | 90° |
视野(mm) | 240×240 | 250×250 |
矩阵 | 256×256 | 64×64 |
层厚(mm) | 1.2 | 3.6 |
层数 | 136 | 35 |
扫描时间(s) | 215 | 360 |
组别 | 例数 | 性别(男/女) | 年龄( | 受教育年限( | NCT-A评分( | DST评分( | MoCA评分( |
---|---|---|---|---|---|---|---|
健康对照组 | 34 | 24/10 | 44.6±7.1 | 7.9±1.6 | 36.3±8.4b | 46.3±9.6b | 26.6±1.8b |
肝硬化组 | 30 | 18/12 | 46.9±9.2 | 8.1±1.5 | 38.4±13.4b | 43.2±5.0b | 26.2±1.8b |
MHE组 | 28 | 19/9 | 47.0±9.3 | 7.8±1.6 | 70.0±14.0 | 21.1±5.0 | 20.3±3.6 |
F(χ2)值 | 0.843a | 0.801 | 0.952 | 72.473 | 117.516 | 59.567 | |
P值 | 0.656 | 0.452 | 0.392 | <0.001 | <0.001 | <0.001 |
Table 2 Comparison of clinical data among healthy control,cirrhosis and MHE groups
组别 | 例数 | 性别(男/女) | 年龄( | 受教育年限( | NCT-A评分( | DST评分( | MoCA评分( |
---|---|---|---|---|---|---|---|
健康对照组 | 34 | 24/10 | 44.6±7.1 | 7.9±1.6 | 36.3±8.4b | 46.3±9.6b | 26.6±1.8b |
肝硬化组 | 30 | 18/12 | 46.9±9.2 | 8.1±1.5 | 38.4±13.4b | 43.2±5.0b | 26.2±1.8b |
MHE组 | 28 | 19/9 | 47.0±9.3 | 7.8±1.6 | 70.0±14.0 | 21.1±5.0 | 20.3±3.6 |
F(χ2)值 | 0.843a | 0.801 | 0.952 | 72.473 | 117.516 | 59.567 | |
P值 | 0.656 | 0.452 | 0.392 | <0.001 | <0.001 | <0.001 |
相关脑区 | 位置 | 体素簇 | MNI坐标 | t值 | ||
---|---|---|---|---|---|---|
X | Y | Z | ||||
MHE组与健康对照组 | ||||||
额中回(升高) | 右 | 27 | 33 | 0 | 48 | 3.760 |
颞中回(升高) | 左 | 37 | -39 | -57 | 21 | -3.901 |
顶下小叶(升高) | 右 | 43 | 51 | -36 | 21 | 3.530 |
枕中回(降低) | 右 | 33 | 26 | -92 | 12 | -3.918 |
角回(降低) | 左 | 27 | -40 | -52 | 22 | -3.900 |
中央前回(降低) | 右 | 25 | 2 | -27 | 57 | -3.968 |
肝硬化组与健康对照组 | ||||||
颞中回(升高) | 左 | 51 | -57 | -60 | -6 | 3.973 |
颞中回(升高) | 右 | 121 | 66 | -51 | -9 | 5.117 |
角回(降低) | 左 | 19 | -44 | -55 | 20 | -3.331 |
MHE组与肝硬化组 | ||||||
楔前叶(降低) | 左 | 22 | -13 | -71 | 26 | -3.464 |
颞中回(降低) | 右 | 25 | 59 | -56 | -3 | -3.870 |
Table 3 Comparison of DC values in brain regions among the healthy control,cirrhosis and MHE groups
相关脑区 | 位置 | 体素簇 | MNI坐标 | t值 | ||
---|---|---|---|---|---|---|
X | Y | Z | ||||
MHE组与健康对照组 | ||||||
额中回(升高) | 右 | 27 | 33 | 0 | 48 | 3.760 |
颞中回(升高) | 左 | 37 | -39 | -57 | 21 | -3.901 |
顶下小叶(升高) | 右 | 43 | 51 | -36 | 21 | 3.530 |
枕中回(降低) | 右 | 33 | 26 | -92 | 12 | -3.918 |
角回(降低) | 左 | 27 | -40 | -52 | 22 | -3.900 |
中央前回(降低) | 右 | 25 | 2 | -27 | 57 | -3.968 |
肝硬化组与健康对照组 | ||||||
颞中回(升高) | 左 | 51 | -57 | -60 | -6 | 3.973 |
颞中回(升高) | 右 | 121 | 66 | -51 | -9 | 5.117 |
角回(降低) | 左 | 19 | -44 | -55 | 20 | -3.331 |
MHE组与肝硬化组 | ||||||
楔前叶(降低) | 左 | 22 | -13 | -71 | 26 | -3.464 |
颞中回(降低) | 右 | 25 | 59 | -56 | -3 | -3.870 |
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