Abstract:

Chronic obstructive pulmonary disease (COPD) is a common, chronic heterogeneous airway disease. Although recent years have witnessed growing advances in both COPD research and management, there are still many difficulties need to be solved urgently. In view of this, the Lancet published Towards the Elimination of Chronic Obstructive Pulmonary Disease in September 2022, a document in which new ideas on the recognition, diagnosis, assessment and individualized treatment of COPD and relevant clinical guidance were proposed. This article focuses on the introduction and interpretation of the classification, diagnostic criteria and diagnostic recommendations of COPD in this document, the acute exacerbation of COPD and the move towards elimination of COPD, hoping to provide insights into COPD research and management conducted by Chinese clinical workers.

Key words: Pulmonary disease, chronic obstructive, Acute exacerbation, Smoking, Classification, Diagnosis, Therapy, Disease management, Interpretation

摘要：

慢性阻塞性肺疾病（以下简称慢阻肺）是一种常见的慢性气道异质性疾病。近年来，尽管国内外慢阻肺相关研究不断深入，管理日趋完善，但仍有许多难点亟待解决。2022年9月，《柳叶刀》杂志发布《消除慢阻肺之路》，该文件针对慢阻肺的认识、诊断、评估和个体化治疗等方面提出了新理念并提供临床诊疗指导。本文重点对该文件中慢阻肺的分类、诊断标准及诊断建议、慢阻肺的急性加重和迈向消除慢阻肺5个方面进行介绍和解读，以期为我国临床工作者开展慢阻肺相关研究和管理提供一定的参考及启示。

关键词: 肺疾病, 慢性阻塞性, 急性加重期, 吸烟, 分类, 诊断, 治疗, 疾病管理, 解读