Latest Developments in the Effects of
Intermittent Fasting on Weight Loss and Glycolipid Metabolism

doi:10.12114/j.issn.1007-9572.2021.00.329

Abstract

Abstract:

Dietary intervention is an important approach to treating obesity. Intermittent fasting (IF) is a eating pattern alternating between eating and energy-restricted fasting or fasting periods, whose types mainly include alternate-day fasting, periodic fasting, time-restricted fasting, Ramadan fasting and so on. Available research has shown that IF manages obesity and obesity-related metabolic disorders to improve health through a variety of mechanisms, but there is no conclusive evidence as to which IF regimen is more sustainable and effective. To provide evidence for in-depth promotion of the application of IF, we introduced several common IF regimens, and reviewed the latest developments in the effects and safety of IF in losing weight, and improving blood glucose and lipids, and found that IF is beneficial to weight loss, blood glucose and lipids reduction, as well as insulin resistance decrease with relatively high safety, but attentions should be paid to individual differences during the actual implementation of IF.

Key words: Intermittent fasting, Obesity, Weight loss, Glucose metabolism, Lipid metabolism

摘要：

饮食干预是治疗肥胖的重要措施。间歇性禁食（IF）是一种正常能量和能量限制（或完全禁食）交替进行的膳食模式，主要类型包括隔日禁食、周期性禁食、限时禁食、斋月禁食等。现有研究表明，IF可通过多种机制改善肥胖及相关代谢紊乱，并促进健康。然而，何种IF方案对肥胖及相关代谢紊乱的干预效果更佳目前尚无定论。本文在介绍IF常见方案的基础上，针对IF在减轻体质量，改善血糖、血脂等方面发挥的作用及IF疗法的安全性进行综述，旨在为IF的深度推广、运用提供依据。本研究发现，IF不仅对减重有益，还有助于降低血糖和体脂，改善血脂谱，减轻胰岛素抵抗。同时IF具有较高的安全性，但在实施时仍需关注个体差异，结合个体实际。

关键词: 间歇性禁食, 肥胖, 减重, 糖代谢, 脂代谢

CLC Number:

R163R459.3

BA Tao, WANG Xiaoli, CHANG Xiangyun.

Latest Developments in the Effects of Intermittent Fasting on Weight Loss and Glycolipid Metabolism [J]. Chinese General Practice, 2022, 25(01): 122-126.

巴涛,王晓丽,常向云. 间歇性禁食对减重和糖脂代谢作用的研究进展[J]. 中国全科医学, 2022, 25(01): 122-126. DOI: 10.12114/j.issn.1007-9572.2021.00.329.

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Latest Developments in the Effects of Intermittent Fasting on Weight Loss and Glycolipid Metabolism

间歇性禁食对减重和糖脂代谢作用的研究进展

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