Risk Factors and Protective Factors for the Progression of Mild Cognitive Impairment Towards Dementia

doi:10.12114/j.issn.1007-9572.2018.33.022

Abstract

Abstract: As the aging of the community population has progressed，the prevalence of dementia has increased every year.Because of the poor treatment efficacy for dementia in the middle and late stages，early recognition of cognitive dysfunction has become a focus of research in the field of gerontology.Previous studies on the causes of cognitive dysfunction have primarily focused on mild cognitive impairment （MCI） or dementia.This article focuses on the progression of MCI towards dementia and explores possible cognitive risks and protective factors in the advanced stages，to provide strategies to prevent or slow the progression of cognitive disorders.

Key words: Mild cognitive impairment, Dementia, Risk factors, Protective factors

摘要： 随着社会人口老龄化的进展，痴呆的患病率逐年增加。由于痴呆中晚期治疗效果欠佳，早期识别认知功能障碍已成为老年医学领域研究的焦点。既往认知功能障碍归因学研究多集中于轻度认知功能障碍（MCI）阶段或痴呆阶段，本文聚焦MCI向痴呆进展阶段，探索进展期可能的认知功能危险性因素及其保护性因素，以期为阻止或减缓认知功能障碍的进展提供公共预防策略。

关键词: 轻度认知障碍, 痴呆, 危险因素, 保护因素

ZHOU Yuanyuan,ZHOU Xianglian,WANG Jie, et al. Risk Factors and Protective Factors for the Progression of Mild Cognitive Impairment Towards Dementia[J]. Chinese General Practice, 2018, 21(33): 4149-4156. DOI: 10.12114/j.issn.1007-9572.2018.33.022.
周媛媛,周香莲,王杰等. 轻度认知功能障碍向痴呆进展的危险因素及保护因素研究[J]. 中国全科医学, 2018, 21(33): 4149-4156. DOI: 10.12114/j.issn.1007-9572.2018.33.022.

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