
Chinese General Practice ›› 2026, Vol. 29 ›› Issue (16): 2198-2204.DOI: 10.12114/j.issn.1007-9572.2025.0420
Special Issue: 内分泌代谢性疾病最新文章合辑; 社区卫生服务最新研究合辑
• Original Research • Previous Articles Next Articles
Received:2025-08-14
Revised:2026-01-10
Published:2026-06-05
Online:2026-05-21
Contact:
XU Ying
通讯作者:
徐英
作者简介:作者贡献:
徐萍负责数据收集、采集、清洗、统计学分析、绘制图表和论文起草;马艳、黄莉、何梅亮负责动员、组织、协调研究对象和调查实施;侯云凤、王德旺、孙盼盼、刘峥负责数据收集、采集、样品转运;郭艳芳负责项目点现场协调;徐英负责文章的质量控制与审查,对文章整体负责,监督管理。
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| 组别 | 例数 | 年龄( | 年龄[例(%)] | 性别[例(%)] | 民族[例(%)] | 婚姻状况[例(%)] | |||||
|---|---|---|---|---|---|---|---|---|---|---|---|
| <45岁 | ≥45岁 | 男 | 女 | 汉族 | 其他 | 未婚 | 已婚/同居 | 丧偶/离异/分居 | |||
| Q1组 | 466 | 33.4±8.0 | 427(91.63) | 39(8.37) | 142(30.47) | 324(69.53) | 430(92.27) | 36(7.73) | 188(40.34) | 259(55.58) | 19(4.08) |
| Q2组 | 460 | 39.1±9.6 | 346(75.22) | 114(24.78) | 224(48.70) | 236(51.30) | 437(95.00) | 23(5.00) | 97(21.09) | 345(75.00) | 18(3.91) |
| Q3组 | 462 | 43.4±10.7 | 270(58.44) | 192(41.56) | 309(66.88) | 153(33.12) | 443(95.89) | 19(4.11) | 68(14.72) | 370(80.09) | 24(5.19) |
| Q4组 | 458 | 51.3±11.2 | 140(30.57) | 318(69.43) | 248(54.15) | 210(45.85) | 439(94.75) | 19(5.25) | 19(4.15) | 411(89.74) | 28(6.11) |
| χ2(F)值 | 550.78a | 408.34 | 127.22 | 8.11 | 200.77 | ||||||
| P值 | <0.001 | <0.001 | <0.001 | 0.044 | <0.001 | ||||||
| 组别 | 文化程度[例(%)] | 参加医疗保险[例(%)] | 年收入[例(%)] | ||||||||
| 小学及以下 | 初中 | 高中/中专/技校 | 大专 | 本科及以上 | 是 | 否 | <12.0万元 | 12.0万~24.9万元 | ≥25.0万元 | ||
| Q1组 | 9(1.93) | 64(13.73) | 101(21.67) | 166(35.62) | 126(27.04) | 451(96.78) | 15(3.22) | 189(40.56) | 183(39.27) | 94(20.17) | |
| Q2组 | 21(4.57) | 100(21.74) | 108(23.48) | 129(28.04) | 102(22.17) | 439(95.43) | 21(4.57) | 160(34.78) | 180(39.13) | 120(26.09) | |
| Q3组 | 45(9.74) | 117(25.32) | 122(26.41) | 97(21.00) | 81(17.53) | 446(96.54) | 16(3.46) | 201(43.51) | 155(33.55) | 106(22.94) | |
| Q4组 | 96(20.96) | 152(33.19) | 103(22.49) | 65(14.19) | 42(9.17) | 436(95.20) | 22(4.80) | 206(44.98) | 149(32.53) | 103(22.49) | |
| χ2(F)值 | 236.42 | 2.24 | 15.34 | ||||||||
| P值 | <0.001 | 0.525 | 0.018 | ||||||||
| 组别 | 吸烟[例(%)] | 饮酒[例(%)] | 中高强度活动[例(%)] | BMI ( | WC ( | ||||||
| 是 | 过去吸烟 | 从不吸烟 | 是 | 否 | 有 | 无 | |||||
| Q1组 | 57(12.23) | 11(2.36) | 398(85.41) | 246(52.79) | 220(47.21) | 396(84.98) | 70(15.02) | 21.77±2.91 | 70.48±6.79 | ||
| Q2组 | 89(19.35) | 19(4.13) | 352(76.52) | 268(58.26) | 192(41.74) | 381(82.83) | 79(17.17) | 23.78±3.27 | 78.78±7.68 | ||
| Q3组 | 125(27.06) | 32(6.93) | 305(66.02) | 262(56.71) | 200(43.29) | 390(84.42) | 72(15.58) | 25.28±3.19 | 85.90±8.23 | ||
| Q4组 | 129(28.17) | 28(6.11) | 301(65.72) | 230(50.22) | 228(49.78) | 387(84.50) | 71(15.50) | 26.46±3.37 | 91.14±8.66 | ||
| χ2(F)值 | 64.26 | 7.47 | 0.91 | 488.14a | 950.75a | ||||||
| P值 | <0.001 | 0.058 | 0.823 | <0.001 | <0.001 | ||||||
| 组别 | Cr ( | UA ( | 高血压[例(%)] | 糖尿病[例(%)] | 血脂异常[例(%)] | "三高"共病[例(%)] | |||||
| 是 | 否 | 是 | 否 | 是 | 否 | 是 | 否 | ||||
| Q1组 | 66.67±14.22 | 342.02±86.95 | 23(4.94) | 443(95.06) | 4(0.86) | 462(99.14) | 71(15.24) | 395(84.76) | 10(2.15) | 456(97.85) | |
| Q2组 | 70.00±16.14 | 378.43±106.27 | 88(19.13) | 372(80.87) | 16(3.48) | 444(96.52) | 134(29.13) | 326(70.87) | 40(8.70) | 420(91.30) | |
| Q3组 | 77.34±63.21 | 415.76±109.19 | 138(29.87) | 324(70.13) | 38(8.23) | 424(91.77) | 220(47.62) | 242(52.38) | 96(20.78) | 366(79.22) | |
| Q4组 | 71.16±15.92 | 401.53±101.31 | 235(51.31) | 223(48.69) | 95(20.74) | 363(79.26) | 236(51.53) | 222(48.47) | 169(36.90) | 289(63.10) | |
| χ2(F)值 | 65.83a | 141.78a | 273.31 | 141.30 | 172.00 | 227.88 | |||||
| P值 | <0.001 | <0.001 | <0.001 | <0.001 | <0.001 | <0.001 | |||||
Table 1 Comparison of baseline characteristics of study participants stratified by WWI
| 组别 | 例数 | 年龄( | 年龄[例(%)] | 性别[例(%)] | 民族[例(%)] | 婚姻状况[例(%)] | |||||
|---|---|---|---|---|---|---|---|---|---|---|---|
| <45岁 | ≥45岁 | 男 | 女 | 汉族 | 其他 | 未婚 | 已婚/同居 | 丧偶/离异/分居 | |||
| Q1组 | 466 | 33.4±8.0 | 427(91.63) | 39(8.37) | 142(30.47) | 324(69.53) | 430(92.27) | 36(7.73) | 188(40.34) | 259(55.58) | 19(4.08) |
| Q2组 | 460 | 39.1±9.6 | 346(75.22) | 114(24.78) | 224(48.70) | 236(51.30) | 437(95.00) | 23(5.00) | 97(21.09) | 345(75.00) | 18(3.91) |
| Q3组 | 462 | 43.4±10.7 | 270(58.44) | 192(41.56) | 309(66.88) | 153(33.12) | 443(95.89) | 19(4.11) | 68(14.72) | 370(80.09) | 24(5.19) |
| Q4组 | 458 | 51.3±11.2 | 140(30.57) | 318(69.43) | 248(54.15) | 210(45.85) | 439(94.75) | 19(5.25) | 19(4.15) | 411(89.74) | 28(6.11) |
| χ2(F)值 | 550.78a | 408.34 | 127.22 | 8.11 | 200.77 | ||||||
| P值 | <0.001 | <0.001 | <0.001 | 0.044 | <0.001 | ||||||
| 组别 | 文化程度[例(%)] | 参加医疗保险[例(%)] | 年收入[例(%)] | ||||||||
| 小学及以下 | 初中 | 高中/中专/技校 | 大专 | 本科及以上 | 是 | 否 | <12.0万元 | 12.0万~24.9万元 | ≥25.0万元 | ||
| Q1组 | 9(1.93) | 64(13.73) | 101(21.67) | 166(35.62) | 126(27.04) | 451(96.78) | 15(3.22) | 189(40.56) | 183(39.27) | 94(20.17) | |
| Q2组 | 21(4.57) | 100(21.74) | 108(23.48) | 129(28.04) | 102(22.17) | 439(95.43) | 21(4.57) | 160(34.78) | 180(39.13) | 120(26.09) | |
| Q3组 | 45(9.74) | 117(25.32) | 122(26.41) | 97(21.00) | 81(17.53) | 446(96.54) | 16(3.46) | 201(43.51) | 155(33.55) | 106(22.94) | |
| Q4组 | 96(20.96) | 152(33.19) | 103(22.49) | 65(14.19) | 42(9.17) | 436(95.20) | 22(4.80) | 206(44.98) | 149(32.53) | 103(22.49) | |
| χ2(F)值 | 236.42 | 2.24 | 15.34 | ||||||||
| P值 | <0.001 | 0.525 | 0.018 | ||||||||
| 组别 | 吸烟[例(%)] | 饮酒[例(%)] | 中高强度活动[例(%)] | BMI ( | WC ( | ||||||
| 是 | 过去吸烟 | 从不吸烟 | 是 | 否 | 有 | 无 | |||||
| Q1组 | 57(12.23) | 11(2.36) | 398(85.41) | 246(52.79) | 220(47.21) | 396(84.98) | 70(15.02) | 21.77±2.91 | 70.48±6.79 | ||
| Q2组 | 89(19.35) | 19(4.13) | 352(76.52) | 268(58.26) | 192(41.74) | 381(82.83) | 79(17.17) | 23.78±3.27 | 78.78±7.68 | ||
| Q3组 | 125(27.06) | 32(6.93) | 305(66.02) | 262(56.71) | 200(43.29) | 390(84.42) | 72(15.58) | 25.28±3.19 | 85.90±8.23 | ||
| Q4组 | 129(28.17) | 28(6.11) | 301(65.72) | 230(50.22) | 228(49.78) | 387(84.50) | 71(15.50) | 26.46±3.37 | 91.14±8.66 | ||
| χ2(F)值 | 64.26 | 7.47 | 0.91 | 488.14a | 950.75a | ||||||
| P值 | <0.001 | 0.058 | 0.823 | <0.001 | <0.001 | ||||||
| 组别 | Cr ( | UA ( | 高血压[例(%)] | 糖尿病[例(%)] | 血脂异常[例(%)] | "三高"共病[例(%)] | |||||
| 是 | 否 | 是 | 否 | 是 | 否 | 是 | 否 | ||||
| Q1组 | 66.67±14.22 | 342.02±86.95 | 23(4.94) | 443(95.06) | 4(0.86) | 462(99.14) | 71(15.24) | 395(84.76) | 10(2.15) | 456(97.85) | |
| Q2组 | 70.00±16.14 | 378.43±106.27 | 88(19.13) | 372(80.87) | 16(3.48) | 444(96.52) | 134(29.13) | 326(70.87) | 40(8.70) | 420(91.30) | |
| Q3组 | 77.34±63.21 | 415.76±109.19 | 138(29.87) | 324(70.13) | 38(8.23) | 424(91.77) | 220(47.62) | 242(52.38) | 96(20.78) | 366(79.22) | |
| Q4组 | 71.16±15.92 | 401.53±101.31 | 235(51.31) | 223(48.69) | 95(20.74) | 363(79.26) | 236(51.53) | 222(48.47) | 169(36.90) | 289(63.10) | |
| χ2(F)值 | 65.83a | 141.78a | 273.31 | 141.30 | 172.00 | 227.88 | |||||
| P值 | <0.001 | <0.001 | <0.001 | <0.001 | <0.001 | <0.001 | |||||
| 变量 | 模型1 | 模型2 | 模型3 | |||
|---|---|---|---|---|---|---|
| OR(95%CI) | P值 | OR(95%CI) | P值 | OR(95%CI) | P值 | |
| WWI(以实测值纳入) | 4.69(3.78~5.83) | <0.001 | 3.15(2.43~4.08) | <0.001 | 2.74(2.08~3.59) | <0.001 |
| WWI四分位组 | ||||||
| Q1组 | 1.00 | 1.00 | 1.00 | |||
| Q2组 | 4.34(2.14~8.79) | <0.001 | 2.81(1.37~5.75) | 0.005 | 2.62(1.26~5.42) | 0.010 |
| Q3组 | 11.96(6.15~23.27) | <0.001 | 5.52(2.77~11.00) | <0.001 | 4.68(2.31~9.48) | <0.001 |
| Q4组 | 26.67(13.86~51.32) | <0.001 | 10.11(5.05~20.23) | <0.001 | 8.09(3.95~16.56) | <0.001 |
Table 2 Logistic regression analysis of the association between WWI and comorbidity of hypertension, diabetes and dyslipidemia in community-dwelling adults
| 变量 | 模型1 | 模型2 | 模型3 | |||
|---|---|---|---|---|---|---|
| OR(95%CI) | P值 | OR(95%CI) | P值 | OR(95%CI) | P值 | |
| WWI(以实测值纳入) | 4.69(3.78~5.83) | <0.001 | 3.15(2.43~4.08) | <0.001 | 2.74(2.08~3.59) | <0.001 |
| WWI四分位组 | ||||||
| Q1组 | 1.00 | 1.00 | 1.00 | |||
| Q2组 | 4.34(2.14~8.79) | <0.001 | 2.81(1.37~5.75) | 0.005 | 2.62(1.26~5.42) | 0.010 |
| Q3组 | 11.96(6.15~23.27) | <0.001 | 5.52(2.77~11.00) | <0.001 | 4.68(2.31~9.48) | <0.001 |
| Q4组 | 26.67(13.86~51.32) | <0.001 | 10.11(5.05~20.23) | <0.001 | 8.09(3.95~16.56) | <0.001 |
| 变量 | Q1组 | Q2组 | Q3组 | Q4组 | P交互值 | |||
|---|---|---|---|---|---|---|---|---|
| OR(95%CI) | P值 | OR(95%CI) | P值 | OR(95%CI) | P值 | |||
| 性别 | 0.359 | |||||||
| 男 | 1.00 | 2.07(0.86~4.98) | 0.106 | 3.81(1.65~8.81) | 0.002 | 8.24(3.50~19.48) | <0.001 | |
| 女 | 1.00 | 4.10(1.05~15.97) | 0.042 | 7.93(1.98~31.72) | 0.003 | 8.57(2.08~35.27) | 0.003 | |
| 年龄 | 0.003 | |||||||
| <45岁 | 1.00 | 4.14(1.49~11.57) | 0.007 | 7.68(2.84~20.76) | <0.001 | 26.26(9.39~73.46) | <0.001 | |
| ≥45岁 | 1.00 | 1.10(0.37~3.27) | 0.864 | 2.07(0.74~5.77) | 0.164 | 3.16(1.16~8.62) | 0.024 | |
| BMI | 0.506 | |||||||
| <24.00 kg/m2 | 1.00 | 1.77(0.59~5.33) | 0.311 | 3.32(1.09~10.17) | 0.035 | 2.67(0.79~8.99) | 0.112 | |
| ≥24.00 kg/m2 | 1.00 | 2.08(0.75~5.78) | 0.159 | 2.71(1.01~7.25) | 0.048 | 5.10(1.89~13.77) | 0.001 | |
Table 3 Subgroup analysis of the association between WWI and comorbidity of hypertension, diabetes and dyslipidemia in community-dwelling adults
| 变量 | Q1组 | Q2组 | Q3组 | Q4组 | P交互值 | |||
|---|---|---|---|---|---|---|---|---|
| OR(95%CI) | P值 | OR(95%CI) | P值 | OR(95%CI) | P值 | |||
| 性别 | 0.359 | |||||||
| 男 | 1.00 | 2.07(0.86~4.98) | 0.106 | 3.81(1.65~8.81) | 0.002 | 8.24(3.50~19.48) | <0.001 | |
| 女 | 1.00 | 4.10(1.05~15.97) | 0.042 | 7.93(1.98~31.72) | 0.003 | 8.57(2.08~35.27) | 0.003 | |
| 年龄 | 0.003 | |||||||
| <45岁 | 1.00 | 4.14(1.49~11.57) | 0.007 | 7.68(2.84~20.76) | <0.001 | 26.26(9.39~73.46) | <0.001 | |
| ≥45岁 | 1.00 | 1.10(0.37~3.27) | 0.864 | 2.07(0.74~5.77) | 0.164 | 3.16(1.16~8.62) | 0.024 | |
| BMI | 0.506 | |||||||
| <24.00 kg/m2 | 1.00 | 1.77(0.59~5.33) | 0.311 | 3.32(1.09~10.17) | 0.035 | 2.67(0.79~8.99) | 0.112 | |
| ≥24.00 kg/m2 | 1.00 | 2.08(0.75~5.78) | 0.159 | 2.71(1.01~7.25) | 0.048 | 5.10(1.89~13.77) | 0.001 | |
Figure 2 Comparative ROC curves of WWI, BMI and WC for predicting comorbidity of hypertension, diabetes and dyslipidemia by sex in community-dwelling adults
| 肥胖指标 | AUC(95%CI) | 最佳截断值(cm/ | 特异度 | 灵敏度 | Z值 | P值 |
|---|---|---|---|---|---|---|
| 男 | ||||||
| WWI | 0.742(0.705~0.778) | 10.549 | 0.733 | 0.633 | ||
| BMI | 0.705(0.667~0.742) | 24.362 | 0.476 | 0.823 | -1.812 | 0.070 |
| WC | 0.738(0.702~0.774) | 88.200 | 0.640 | 0.735 | -0.226 | 0.821 |
| 女 | ||||||
| WWI | 0.806(0.768~0.844) | 10.342 | 0.724 | 0.790 | ||
| BMI | 0.717(0.669~0.765) | 23.987 | 0.657 | 0.670 | -3.134 | 0.002 |
| WC | 0.804(0.766~0.842) | 75.475 | 0.578 | 0.900 | -0.118 | 0.906 |
Table 4 The predictive role of WWI, BMI and WC for comorbidity of hypertension, diabetes and dyslipidemia in community-dwelling adults
| 肥胖指标 | AUC(95%CI) | 最佳截断值(cm/ | 特异度 | 灵敏度 | Z值 | P值 |
|---|---|---|---|---|---|---|
| 男 | ||||||
| WWI | 0.742(0.705~0.778) | 10.549 | 0.733 | 0.633 | ||
| BMI | 0.705(0.667~0.742) | 24.362 | 0.476 | 0.823 | -1.812 | 0.070 |
| WC | 0.738(0.702~0.774) | 88.200 | 0.640 | 0.735 | -0.226 | 0.821 |
| 女 | ||||||
| WWI | 0.806(0.768~0.844) | 10.342 | 0.724 | 0.790 | ||
| BMI | 0.717(0.669~0.765) | 23.987 | 0.657 | 0.670 | -3.134 | 0.002 |
| WC | 0.804(0.766~0.842) | 75.475 | 0.578 | 0.900 | -0.118 | 0.906 |
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