Research Progress on the Influence of Nervous System Diseases and Related Therapeutic Drugs on Osteoporosis

doi:10.12114/j.issn.1007-9572.2024.0198

Abstract

Abstract:

Patients with osteoporosis (OP) often suffer from a variety of diseases. In addition to general risk factors such as age, gender, race, comorbidities and related treatments can affect bone metabolism. At present, there are relatively few studies on the association between neurological disorders and OP. Therefore, this article intends to review the epidemiological characteristics, bone loss feature, related pathogenesis and progress of diagnosis and treatment, in order to provide reference for the mechanism of bone damage, OP prevention and anti-osteoporosis treatment in patients with nervous system diseases.

Key words: Osteoporosis, Secondary osteoporosis, Stroke, Spinal cord injury, Multiple sclerosis, Parkinson's disease, Alzheimer's disease, Epilepsy, Treatment, Review

摘要：

骨质疏松症（OP）患者常共患多种疾病，除了年龄、性别、种族等一般致OP危险因素外，共患疾病及其相关治疗均可对骨代谢产生影响。目前关于神经系统疾病合并OP相关研究较为缺乏，本文拟从流行病学特征、骨量流失特点、相关发病机制及诊疗进展4个方面进行综述，以期为神经系统疾病患者骨损害机制、OP预防及抗骨质疏松治疗等提供参考。

关键词: 骨质疏松, 继发性骨质疏松症, 脑卒中, 脊髓损伤, 多发性硬化, 帕金森病, 阿尔茨海默病, 癫痫, 治疗, 综述

CLC Number:

R 681

TAN Wenbin,LI Jia,LIU Mingyu, et al. Research Progress on the Influence of Nervous System Diseases and Related Therapeutic Drugs on Osteoporosis[J]. Chinese General Practice, 2025, 28(17): 2092-2100. DOI: 10.12114/j.issn.1007-9572.2024.0198.
谭文彬,李佳,刘明玉等. 神经系统疾病及相关治疗药物对骨质疏松症影响的研究进展[J]. 中国全科医学, 2025, 28(17): 2092-2100. DOI: 10.12114/j.issn.1007-9572.2024.0198.

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