
Chinese General Practice ›› 2024, Vol. 27 ›› Issue (06): 711-716.DOI: 10.12114/j.issn.1007-9572.2023.0333
Special Issue: 老年问题最新文章合辑; 远程医疗最新文章合辑; 疾病康复与健康最新文章合辑; 呼吸疾病文章合辑; 数智医疗最新文章合辑; 老年人群健康最新文章合辑
• Original Research • Previous Articles Next Articles
Received:2023-05-10
Revised:2023-08-20
Published:2024-02-20
Online:2023-11-21
Contact:
LU Haiying
通讯作者:
陆海英
作者简介:基金资助:
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URL: https://www.chinagp.net/EN/10.12114/j.issn.1007-9572.2023.0333
| 组别 | 例数 | 性别(男/女) | 年龄(岁) | FEV1%pred | FEV1/FVC(%) |
|---|---|---|---|---|---|
| 对照组 | 72 | 41/31 | 75.2±5.9 | 33.10±10.50 | 58.31±15.20 |
| 试验组 | 73 | 44/29 | 74.6±6.1 | 32.30±11.40 | 59.23±16.10 |
| t(χ2)值 | 0.166a | 0.850 | 0.620 | 0.499 | |
| P值 | 0.684 | 0.396 | 0.536 | 0.618 |
Table 1 Comparison of baseline data between the two groups of patients
| 组别 | 例数 | 性别(男/女) | 年龄(岁) | FEV1%pred | FEV1/FVC(%) |
|---|---|---|---|---|---|
| 对照组 | 72 | 41/31 | 75.2±5.9 | 33.10±10.50 | 58.31±15.20 |
| 试验组 | 73 | 44/29 | 74.6±6.1 | 32.30±11.40 | 59.23±16.10 |
| t(χ2)值 | 0.166a | 0.850 | 0.620 | 0.499 | |
| P值 | 0.684 | 0.396 | 0.536 | 0.618 |
| 组别 | 例数 | FEV1% | FEV1/FVC(%) | ||||||
|---|---|---|---|---|---|---|---|---|---|
| 入组前 | 1个月后 | 3个月后 | 6个月后 | 入组前 | 1个月后 | 3个月后 | 6个月后 | ||
| 对照组 | 72 | 33.07±11.13 | 34.22±10.81 | 34.89±11.41 | 33.91±11.78 | 56.31±15.04 | 57.67±14.67 | 57.96±15.54 | 57.29±15.78 |
| 试验组 | 73 | 32.35±12.12 | 35.68±12.00a | 39.44±11.40ab | 40.30±12.25ab | 59.27±16.05 | 66.57±15.31a | 64.74±16.18ab | 67.20±14.85ab |
| 整体分析 | HF系数=1.013 | HF系数=1.005 | |||||||
| F值 | F组间=19.406,F时间=9.360,F交互=5.240 | F组间=63.079,F时间=5.259,F交互=2.833 | |||||||
| P值 | P组间<0.001,P时间<0.001,P交互=0.001 | P组间<0.001,P时间=0.001,P交互=0.037 | |||||||
Table 2 Comparison of pulmonary function test results between the two groups of patients before and at 1,3,and 6 months after intervention
| 组别 | 例数 | FEV1% | FEV1/FVC(%) | ||||||
|---|---|---|---|---|---|---|---|---|---|
| 入组前 | 1个月后 | 3个月后 | 6个月后 | 入组前 | 1个月后 | 3个月后 | 6个月后 | ||
| 对照组 | 72 | 33.07±11.13 | 34.22±10.81 | 34.89±11.41 | 33.91±11.78 | 56.31±15.04 | 57.67±14.67 | 57.96±15.54 | 57.29±15.78 |
| 试验组 | 73 | 32.35±12.12 | 35.68±12.00a | 39.44±11.40ab | 40.30±12.25ab | 59.27±16.05 | 66.57±15.31a | 64.74±16.18ab | 67.20±14.85ab |
| 整体分析 | HF系数=1.013 | HF系数=1.005 | |||||||
| F值 | F组间=19.406,F时间=9.360,F交互=5.240 | F组间=63.079,F时间=5.259,F交互=2.833 | |||||||
| P值 | P组间<0.001,P时间<0.001,P交互=0.001 | P组间<0.001,P时间=0.001,P交互=0.037 | |||||||
| 组别 | 例数 | Borg评分(分) | 6MWT(m) | ||||||
|---|---|---|---|---|---|---|---|---|---|
| 入组前 | 1个月后 | 3个月后 | 6个月后 | 入组前 | 1个月后 | 3个月后 | 6个月后 | ||
| 对照组 | 72 | 4.22±1.93 | 3.93±2.01 | 3.89±1.88 | 3.96±1.97 | 263.5±50.8 | 278.2±51.1 | 275.9±50.0 | 269.8±51.0 |
| 试验组 | 73 | 4.11±2.13 | 3.24±1.89a | 3.16±2.01ab | 3.09±1.98ab | 263.1±51.3 | 316.8±48.9a | 330.9±50.4ab | 345.5±51.6ab |
| 整体分析 | HF系数=1.003 | HF系数=1.013 | |||||||
| F值 | F组间=24.830,F时间=7.406,F交互=2.146 | F组间=206.407,F时间=45.428,F交互=28.927 | |||||||
| P值 | P组间<0.001,P时间<0.001,P交互=0.093 | P组间<0.001,P时间<0.001,P交互<0.001 | |||||||
Table 3 Comparison of pulmonary function test results between the two groups of patients before test and after 1,3,and 6 months intervention
| 组别 | 例数 | Borg评分(分) | 6MWT(m) | ||||||
|---|---|---|---|---|---|---|---|---|---|
| 入组前 | 1个月后 | 3个月后 | 6个月后 | 入组前 | 1个月后 | 3个月后 | 6个月后 | ||
| 对照组 | 72 | 4.22±1.93 | 3.93±2.01 | 3.89±1.88 | 3.96±1.97 | 263.5±50.8 | 278.2±51.1 | 275.9±50.0 | 269.8±51.0 |
| 试验组 | 73 | 4.11±2.13 | 3.24±1.89a | 3.16±2.01ab | 3.09±1.98ab | 263.1±51.3 | 316.8±48.9a | 330.9±50.4ab | 345.5±51.6ab |
| 整体分析 | HF系数=1.003 | HF系数=1.013 | |||||||
| F值 | F组间=24.830,F时间=7.406,F交互=2.146 | F组间=206.407,F时间=45.428,F交互=28.927 | |||||||
| P值 | P组间<0.001,P时间<0.001,P交互=0.093 | P组间<0.001,P时间<0.001,P交互<0.001 | |||||||
| 组别 | 例数 | 呼吸困难 | 活动能力 | ||||||
|---|---|---|---|---|---|---|---|---|---|
| 入组前 | 1个月后 | 3个月后 | 6个月后 | 入组前 | 1个月后 | 3个月后 | 6个月后 | ||
| 对照组 | 72 | 39.9±17.3 | 39.0±17.9 | 41.0±19.1 | 38.9±18.2 | 45.1±21.2 | 42.9±19.3 | 44.9±20.5 | 43.9±20.2 |
| 试验组 | 73 | 41.1±19.0 | 33.0±22.1a | 32.0±24.5ab | 31.9±22.9ab | 46.0±23.3 | 47.1±23.0a | 51.1±24.6ab | 50.9±24.6ab |
| 整体分析 | HF系数=0.980 | HF系数=1.004 | |||||||
| F值 | F组间=19.427,F时间=3.711,F交互=3.378 | F组间=13.883,F时间=1.177,F交互=1.053 | |||||||
| P值 | P组间<0.001,P时间=0.025,P交互=0.035 | P组间<0.001,P时间=0.317,P交互=0.368 | |||||||
Table 4 Comparison of QOL dyspnea,mobility scores at 1,3,and 6 months between the two groups of patients
| 组别 | 例数 | 呼吸困难 | 活动能力 | ||||||
|---|---|---|---|---|---|---|---|---|---|
| 入组前 | 1个月后 | 3个月后 | 6个月后 | 入组前 | 1个月后 | 3个月后 | 6个月后 | ||
| 对照组 | 72 | 39.9±17.3 | 39.0±17.9 | 41.0±19.1 | 38.9±18.2 | 45.1±21.2 | 42.9±19.3 | 44.9±20.5 | 43.9±20.2 |
| 试验组 | 73 | 41.1±19.0 | 33.0±22.1a | 32.0±24.5ab | 31.9±22.9ab | 46.0±23.3 | 47.1±23.0a | 51.1±24.6ab | 50.9±24.6ab |
| 整体分析 | HF系数=0.980 | HF系数=1.004 | |||||||
| F值 | F组间=19.427,F时间=3.711,F交互=3.378 | F组间=13.883,F时间=1.177,F交互=1.053 | |||||||
| P值 | P组间<0.001,P时间=0.025,P交互=0.035 | P组间<0.001,P时间=0.317,P交互=0.368 | |||||||
| 组别 | 例数 | 情绪 | 家务工作 | 食欲 | |||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 入组前 | 1个月后 | 3个月后 | 6个月后 | 入组前 | 1个月后 | 3个月后 | 6个月后 | 入组前 | 1个月后 | 3个月后 | 6个月后 | ||
| 对照组 | 72 | 54.1±21.3 | 56.1±20.7 | 55.7±21.0 | 56.0±20.1 | 51.1±28.3 | 51.2±28.1 | 51.9±27.9 | 51.6±28.9 | 52.0±29.1 | 53.0±27.8 | 55.0±26.6 | 53.1±27.8b |
| 试验组 | 73 | 55.2±20.2 | 61.3±17.9a | 67.6±18.3ab | 67.3±17.8ab | 52.0±31.0 | 56.0±30.9a | 58.5±33.4ab | 60.3±32.8ab | 53.0±29.1 | 59.1±26.3a | 58.0±27.5b | 60.1±25.2ab |
| 整体分析 | HF系数=1.016 | HF系数=1.010 | HF系数=0.996 | ||||||||||
| F值 | F组间=46.102,F时间=7.783,F交互=4.645 | F组间=7.626,F时间=1.259,F交互=0.885 | F组间=7.305,F时间=1.449,F交互=0.718 | ||||||||||
| P值 | P组间<0.001,P时间<0.001,P交互=0.003 | P组间=0.006,P时间=0.287,P交互=0.449 | P组间=0.007,P时间=0.235,P交互=0.488 | ||||||||||
Table 5 Comparison of QOL mood,housework,and appetite scores at 1,3,and 6 months between the two groups of patients
| 组别 | 例数 | 情绪 | 家务工作 | 食欲 | |||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 入组前 | 1个月后 | 3个月后 | 6个月后 | 入组前 | 1个月后 | 3个月后 | 6个月后 | 入组前 | 1个月后 | 3个月后 | 6个月后 | ||
| 对照组 | 72 | 54.1±21.3 | 56.1±20.7 | 55.7±21.0 | 56.0±20.1 | 51.1±28.3 | 51.2±28.1 | 51.9±27.9 | 51.6±28.9 | 52.0±29.1 | 53.0±27.8 | 55.0±26.6 | 53.1±27.8b |
| 试验组 | 73 | 55.2±20.2 | 61.3±17.9a | 67.6±18.3ab | 67.3±17.8ab | 52.0±31.0 | 56.0±30.9a | 58.5±33.4ab | 60.3±32.8ab | 53.0±29.1 | 59.1±26.3a | 58.0±27.5b | 60.1±25.2ab |
| 整体分析 | HF系数=1.016 | HF系数=1.010 | HF系数=0.996 | ||||||||||
| F值 | F组间=46.102,F时间=7.783,F交互=4.645 | F组间=7.626,F时间=1.259,F交互=0.885 | F组间=7.305,F时间=1.449,F交互=0.718 | ||||||||||
| P值 | P组间<0.001,P时间<0.001,P交互=0.003 | P组间=0.006,P时间=0.287,P交互=0.449 | P组间=0.007,P时间=0.235,P交互=0.488 | ||||||||||
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