Exploring the Best Sleep Duration for Undergraduates from the Perspective of TCM Constitution by Using Restricted Cubic Spline Model

doi:10.12114/j.issn.1007-9572.2022.0401

Chinese General Practice ›› 2023, Vol. 26 ›› Issue (06): 718-724.DOI: 10.12114/j.issn.1007-9572.2022.0401

Special Issue: 睡眠研究最新文章合辑；中医最新文章合辑；睡眠问题专题研究

• Population Health Research • Previous Articles Next Articles

Exploring the Best Sleep Duration for Undergraduates from the Perspective of TCM Constitution by Using Restricted Cubic Spline Model

1. School of Management, Beijing University of Chinese Medicine, Beijing 102488, China
2. School of Traditional Chinese Medicine, Beijing University of Chinese Medicine, Beijing 102488, China

Received:2022-05-06 Revised:2022-09-20 Published:2023-02-20 Online:2022-10-27
Contact: ZHU Yanbo
About author:
MA F H, ZHU Y B, LIU W Q, et al. Exploring the best sleep duration for undergraduates from the perspective of TCM constitution by using restricted cubic spline model[J]. Chinese General Practice, 2023, 26 (6) : 718-724, 733.

基于限制性立方样条模型从中医体质角度探讨大学生最佳睡眠时长的研究

1．102488　北京市，北京中医药大学管理学院
2．102488　北京市，北京中医药大学中医学院

通讯作者: 朱燕波
作者简介:
马方晖，朱燕波，刘雯琼，等.基于限制性立方样条模型从中医体质角度探讨大学生最佳睡眠时长的研究[J].中国全科医学，2023，26（6）：718-724，733. [www.chinagp.net] 作者贡献：马方晖、朱燕波进行文章的构思设计，撰写论文，对论文进行修订；朱燕波组织数据录入和核查；马方晖进行统计学处理，对结果进行分析和解释；马方晖、朱燕波、刘雯琼、吴新瑞、张千、赵心源、李玉琼、龙利群、陈皮皮对论文进行讨论修改；朱燕波负责文章的质量控制及审校、对文章整体负责，监督管理。
基金资助:
北京中医药大学重点攻关项目(2020-JYB-ZDGG-073); 北京中医药大学成果转化专项课题(2019-XJ-CGZH-018); 科技部基础性工作专项(2013FY114400-5)

Abstract

Abstract:

Background

Sleep duration of the undergraduates are closely related to their health, but there is no conclusion about the best sleep duration for undergraduates. And there is a lack of research about the dose-response relationship between sleep duration and Traditional Chinese Medicine (TCM) constitution.

Objective

To explore the relationship between sleep duration and TCM constitution for undergraduates, and to provide reference for their health education about sleep duration.

Methods

This study used a combination of purposeful sampling and snowball sampling methods to conduct on-site questionnaire survey on students from 143 universities including Beijing University of Chinese Medicine, Harbin Institute of Technology (Weihai), Peking University, Northwestern Polytechnical University from January to June 2019. We used the Constitution in Chinese Medicine Questionnaire of 41-item (CCMQ-41) to assess the TCM constitution of undergraduates, and used a self-designed questionnaire to measure socio-demographic information and lifestyle behaviors. This study used the restricted cubic spline fitting multiple linear regression model to analyze the dose-response relationship between sleep duration and TCM constitution with taking sleep duration as the independent variable and TCM constitution score as the dependent variable, and controlling for related confounding variables.

Results

This study collected 1 003 valid questionnaires. The response rate was 98.2%. Pearson correlation analysis showed that the sleep duration was negatively correlated with the score of qi depression (r=-0.067, P=0.034). After controlling for confounders, multiple linear regression analysis showed that there was no linear relationship between sleep duration and TCM constitution scores (P>0.05). The dose-response relationship analysis showed that the highest point of gentleness score and the lowest point of biased constitutions score (except specific diathesis) had a sleep duration of about 8 h. When the sleep duration was >8.5 h, the gentleness score showed a tendency to decrease, and the scores of qi deficiency and qi depression had a tendency to increase (P<0.05) .

Conclusion

Considering the health status of TCM constitutions, the best daily sleep duration for undergraduates is about 8 h. The sleep duration should be restricted to be less than 8.5 h to prevent the possibility of biased constitution.

Key words: TCM constitution, Sleep, Best sleep duration, Undergraduates, Health status

摘要：

背景

睡眠时长与大学生健康密切相关，但关于大学生最佳睡眠时长尚无定论，同时缺乏睡眠时长与中医体质的量效关系研究。

目的

探究大学生睡眠时长与中医体质的关系，为大学生睡眠时长的健康教育提供参考。

方法

2019年1—6月，采用立意抽样结合滚雪球抽样法对北京中医药大学、哈尔滨工业大学（威海）、北京大学、西北工业大学等143所高校在读生进行现场问卷调查。采用中医体质量表-41条目简短版（CCMQ-41）评估大学生中医体质状况，自行设计的一般情况调查表测查大学生的社会人口学信息和生活行为方式。以睡眠时长为自变量，中医体质得分为因变量，控制相关混杂变量，采用限制性立方样条模型拟合多元线性回归模型分析睡眠时长与中医体质状况的剂量-反应关系。

结果

本次调查共收集有效问卷1 003份，有效回收率为98.2%。Pearson相关分析结果显示，睡眠时长与气郁质得分呈负相关（r=-0.067，P=0.034）。控制混杂因素后的多元线性回归分析结果显示，睡眠时长与9种中医体质得分之间不存在线性相关关系（P>0.05）。剂量-反应关系结果显示，平和质得分最高点、偏颇体质得分（特禀质除外）最低点的睡眠时长约为8 h；当睡眠时长>8.5 h时，平和质得分呈现降低趋势，气虚质、气郁质得分有增加趋势（P值均<0.05）。

结论

综合考虑体质整体健康状况，大学生每日最佳睡眠时长约为8 h；同时应控制睡眠时长不大于8.5 h，以防增加偏颇体质发生的可能。

关键词: 中医体质, 睡眠, 最佳睡眠时长, 大学生, 健康状况

MA Fanghui,ZHU Yanbo,LIU Wenqiong, et al. Exploring the Best Sleep Duration for Undergraduates from the Perspective of TCM Constitution by Using Restricted Cubic Spline Model[J]. Chinese General Practice, 2023, 26(06): 718-724. DOI: 10.12114/j.issn.1007-9572.2022.0401.
马方晖,朱燕波,刘雯琼等. 基于限制性立方样条模型从中医体质角度探讨大学生最佳睡眠时长的研究[J]. 中国全科医学, 2023, 26(06): 718-724. DOI: 10.12114/j.issn.1007-9572.2022.0401.

Figures/Tables 3

References 60

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项目	平和质	气虚质	阳虚质	阴虚质	痰湿质	湿热质	血瘀质	气郁质	特禀质
r值	0.035	-0.021	-0.033	-0.052	-0.042	-0.034	-0.049	-0.067	-0.030
P值	0.275	0.497	0.302	0.097	0.180	0.286	0.119	0.034	0.343

项目	平和质	气虚质	阳虚质	阴虚质	痰湿质	湿热质	血瘀质	气郁质	特禀质
r值	0.035	-0.021	-0.033	-0.052	-0.042	-0.034	-0.049	-0.067	-0.030
P值	0.275	0.497	0.302	0.097	0.180	0.286	0.119	0.034	0.343

因变量	β	SE	β'	t值	P值
平和质	0.319	0.515	0.019	0.618	0.537
气虚质	-0.159	0.518	-0.009	-0.306	0.760
阳虚质	-0.411	0.693	-0.018	-0.593	0.553
阴虚质	-0.706	0.552	-0.040	-1.278	0.202
痰湿质	-0.488	0.548	-0.027	-0.890	0.374
湿热质	-0.442	0.567	-0.024	-0.780	0.435
血瘀质	-0.522	0.555	-0.029	-0.941	0.347
气郁质	-0.996	0.553	-0.056	-1.801	0.072
特禀质	-0.432	0.573	-0.024	-0.755	0.451

因变量	β	SE	β'	t值	P值
平和质	0.319	0.515	0.019	0.618	0.537
气虚质	-0.159	0.518	-0.009	-0.306	0.760
阳虚质	-0.411	0.693	-0.018	-0.593	0.553
阴虚质	-0.706	0.552	-0.040	-1.278	0.202
痰湿质	-0.488	0.548	-0.027	-0.890	0.374
湿热质	-0.442	0.567	-0.024	-0.780	0.435
血瘀质	-0.522	0.555	-0.029	-0.941	0.347
气郁质	-0.996	0.553	-0.056	-1.801	0.072
特禀质	-0.432	0.573	-0.024	-0.755	0.451

Exploring the Best Sleep Duration for Undergraduates from the Perspective of TCM Constitution by Using Restricted Cubic Spline Model

基于限制性立方样条模型从中医体质角度探讨大学生最佳睡眠时长的研究

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