New Advances in the Value of the Normal Urinary Albumin as a Predictor of Multiple Diseases

doi:10.12114/j.issn.1007-9572.2022.0240

Abstract

Abstract:

The association of the normal range of urinary albumin and its associated diseases (mainly including diabetic kidney diseases, diabetic retinopathy, cardiovascular disease, and metabolic syndrome) has been an increasing concern, and the range of normal urinary albumin has been questioned by a growing number of scholars. We reviewed the association of the normal range of urinary albumin with the aforementioned diseases and the possible mechanism of actions, to assess the value of normal-range urinary albumin as a predictor of the diseases, and to provide a basis for future redefinition of the threshold for the normal range of urine albumin.

Key words: Albuminuria, Diabetic kidney diseases, Diabetic retinopathy, Cardiovascular diseases, Metabolic syndrome, Review

摘要：

目前，关于正常尿白蛋白水平与相关疾病（包括糖尿病肾病、糖尿病视网膜病变、心血管疾病、代谢综合征等）之间的关系已被逐渐重视，越来越多的研究者也对正常尿白蛋白的范围提出了质疑。本文对正常尿白蛋白水平与不同疾病之间的关系及其可能的机制做一综述，旨在探讨正常尿白蛋白作为疾病预测因子的价值，并为今后正常尿白蛋白阈值的重新界定提供依据。

关键词: 白蛋白尿, 糖尿病肾病, 糖尿病视网膜病变, 心血管疾病, 代谢综合征, 综述

SUN Zhenzhen,LIU Huanhuan,CHEN Kaining, et al. New Advances in the Value of the Normal Urinary Albumin as a Predictor of Multiple Diseases[J]. Chinese General Practice, 2022, 25(33): 4191-4195. DOI: 10.12114/j.issn.1007-9572.2022.0240.
孙珍珍,刘欢欢,陈开宁等. 正常尿白蛋白水平在多种疾病预测中的研究进展[J]. 中国全科医学, 2022, 25(33): 4191-4195. DOI: 10.12114/j.issn.1007-9572.2022.0240.

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