Abstract: Background　The prevalence of hyperuricemia（HUA） and gout in China has been increasing annually in recent years.Their distribution varies across regions.Investigating the disease characteristics and risk factors in a local area can guide the corresponding prevention and treatment services in community practice.There is no statistical analysis of HUA and gout prevalence and the distribution of such patients in Xujiahui Subdistrict，Shanghai.Objective　To investigate the epidemiological characteristics and associated factors of HUA and gout in community-dwelling elderly people aged 65 and over from Xuhui Subdistrict，Shanghai.Methods　From Xujiahui Subdistrict Community Health Center，we enrolled a total of 2 047 elderly physical examinees，some of whom were recruited between April 19 and October 27，2016，and others were recruited between September 4 and October 31，2017.We analyzed the prevalence，and sex and age distributions of HUA，asymptomatic HUA and gout in the participants，and determined the associated factors of HUA by using stepwise multiple Logistic regression.Results　The prevalence of HUA，asymptomatic HUA，and gout was 24.33%（498/2 047），23.35%（478/2 047） and 5.13%（105/2 047），respectively.Higher gout prevalence and lower asymptomatic HUA prevalence were found in male patients than in female patients（P<0.05）．No significant difference was found for HUA between males and females（P>0.05）.The HUA prevalence showed an increase with age（P<0.05） in female patients.Regression analysis indicated older age，overweight and obesity，high TG（≥1.70 mmol/L），and high ALT（>40 U/L） were independent risk factors for HUA（P<0.05）.The prevalence of hypertension，diabetes，cerebrovascular disease，coronary heart disease and osteoporosis in gout patients was much higher than in those with normal uric acid but without gout or in those with asymptomatic HUA（P<0.016 7）.Conclusion　The prevalence of HUA and gout in community-dwelling elderly people in Xujiahui Subdistrict is high，with similar HUA associated factors as found in previous studies，and the prevalence of chronic comorbidity of gout is also high，demanding for increased community-based risk management among high-risk residents，as well as prevention and treatment of comorbidity for gout patients.

Key words: Hyperuricemia, Gout, Community health services, Prevalence, Risk factors, Shanghai

摘要： 背景　我国高尿酸血症（HUA）和痛风患病率逐年上升，HUA和痛风的患病分布具有地域性，分析辖区内居民的患病特征和影响因素可以指导社区防治，但上海市徐家汇街道尚未对辖区内居民的HUA和痛风患病率、患病人口分布等进行统计分析。目的　了解上海市徐家汇街道老年人（≥65岁）的HUA和痛风患病状况，并探讨老年人患HUA的影响因素。方法　以2016-04-19至2016-10-27、2017-09-04至2017-10-31在徐家汇街道社区卫生服务中心完成体检的2 047例老年人为研究对象。统计社区老年人的HUA、无症状HUA、痛风患病率，并分析其性别、年龄分布情况；采用多元逐步Logistic回归分析老年人患HUA的影响因素。结果　老年人的HUA、无症状HUA、痛风患病率分别为24.33%（498/2 047）、23.35%（478/2 047）、5.13%（105/2 047）。男性的痛风患病率高于女性，无症状HUA患病率低于女性（P<0.05）；男性、女性的HUA患病率比较，差异无统计学意义（P>0.05）。女性的HUA患病率随年龄增长而增加（P<0.05）。多元逐步Logistic回归分析结果显示，高龄、超重和肥胖、高三酰甘油血症（≥1.70 mmol/L）、高ALT（>40 U/L）是老年人患HUA的危险因素（P<0.05）。痛风患者的高血压、糖尿病、脑血管病、冠心病、骨质疏松发生率高于血尿酸正常且无痛风者和无症状HUA患者（P<0.016 7）。结论　徐家汇街道老年人的HUA和痛风患病率较高，患HUA的影响因素与既往研究类似。痛风患者的慢性合并症患病率较高，社区应加强对高危居民的管理及对痛风患者合并症的防治。

关键词: 高尿酸血症, 痛风, 社区卫生服务, 患病率, 危险因素, 上海