Chinese General Practice ›› 2023, Vol. 26 ›› Issue (24): 3022-3027.DOI: 10.12114/j.issn.1007-9572.2023.0113
• Original Research • Previous Articles Next Articles
Received:
2023-02-28
Revised:
2023-03-31
Published:
2023-08-20
Online:
2023-04-13
Contact:
DAI Huihua, SUN Ying
通讯作者:
戴辉华, 孙莹
作者简介:
基金资助:
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URL: https://www.chinagp.net/EN/10.12114/j.issn.1007-9572.2023.0113
组别 | 例数 | 因体检首次发现 | 腹痛 | 腹部增大 | 腹胀 | 尿频 | 腹部扪及包块 | 月经异常 |
---|---|---|---|---|---|---|---|---|
MCA组 | 305 | 226(74.1) | 39(12.8) | 12 (3.9) | 14 (4.6) | 4(1.3) | 7(2.3) | 3(1.0) |
MBT组 | 79 | 39(49.4) | 18(22.8) | 5 (6.3) | 11(13.9) | 1(1.3) | 0 | 5(6.3) |
MC组 | 30 | 12(40.0) | 5(16.7) | 5(16.7) | 5(16.7) | 0 | 2(6.7) | 1(3.3) |
合计 | 414 | 277(66.9) | 62(15.0) | 22 (5.3) | 30 (7.2) | 5(1.2) | 9(2.2) | 9(2.2) |
Table 1 Clinical features of three groups
组别 | 例数 | 因体检首次发现 | 腹痛 | 腹部增大 | 腹胀 | 尿频 | 腹部扪及包块 | 月经异常 |
---|---|---|---|---|---|---|---|---|
MCA组 | 305 | 226(74.1) | 39(12.8) | 12 (3.9) | 14 (4.6) | 4(1.3) | 7(2.3) | 3(1.0) |
MBT组 | 79 | 39(49.4) | 18(22.8) | 5 (6.3) | 11(13.9) | 1(1.3) | 0 | 5(6.3) |
MC组 | 30 | 12(40.0) | 5(16.7) | 5(16.7) | 5(16.7) | 0 | 2(6.7) | 1(3.3) |
合计 | 414 | 277(66.9) | 62(15.0) | 22 (5.3) | 30 (7.2) | 5(1.2) | 9(2.2) | 9(2.2) |
组别 | 例数 | B超表现 | 血清学指标 | ||||||||
---|---|---|---|---|---|---|---|---|---|---|---|
卵巢肿瘤最大径≥10 cm | 肿瘤内有实性成分 | 肿瘤内有乳头 | 肿瘤内有血流信号 | 肿瘤表现为多房 | CEA ≥4.7 μg/L | CA125 ≥35.0 U/mL | CA724 ≥6.9 U/mL | CA199 ≥39.0 U/mL | DD2 ≥0.55 U/mL | ||
MCA组 | 305 | 118(37.8) | 14 (4.6) | 31(10.2) | 49(16.1) | 122(40.0) | 8 (2.6) | 23 (7.5) | 34(11.1) | 27 (8.9) | 13 (4.3) |
MBT组 | 79 | 55(69.6)a | 30(38.0)a | 26(32.9)a | 22(27.8)a | 59(74.7)a | 5 (6.3) | 26(32.9)a | 11(13.9) | 23(29.1)a | 9(11.4)a |
MC组 | 30 | 21(70.0)a | 16(53.3)a | 6(20.0) | 8(26.7) | 18(60.0) | 11(36.7)ab | 19(60.0)ab | 14(46.7)ab | 13(43.3)a | 6(20.0)a |
χ2值 | 31.064 | 95.807 | 25.739 | 6.847 | 32.083 | 33.363 | 75.553 | 28.207 | 39.783 | 14.046 | |
P值 | <0.001 | <0.001 | <0.001 | 0.033 | <0.001 | <0.001 | <0.001 | <0.001 | <0.001 | 0.001 |
Table 2 B-mode ultrasound manifestations and levels of serum tumor markers between three groups
组别 | 例数 | B超表现 | 血清学指标 | ||||||||
---|---|---|---|---|---|---|---|---|---|---|---|
卵巢肿瘤最大径≥10 cm | 肿瘤内有实性成分 | 肿瘤内有乳头 | 肿瘤内有血流信号 | 肿瘤表现为多房 | CEA ≥4.7 μg/L | CA125 ≥35.0 U/mL | CA724 ≥6.9 U/mL | CA199 ≥39.0 U/mL | DD2 ≥0.55 U/mL | ||
MCA组 | 305 | 118(37.8) | 14 (4.6) | 31(10.2) | 49(16.1) | 122(40.0) | 8 (2.6) | 23 (7.5) | 34(11.1) | 27 (8.9) | 13 (4.3) |
MBT组 | 79 | 55(69.6)a | 30(38.0)a | 26(32.9)a | 22(27.8)a | 59(74.7)a | 5 (6.3) | 26(32.9)a | 11(13.9) | 23(29.1)a | 9(11.4)a |
MC组 | 30 | 21(70.0)a | 16(53.3)a | 6(20.0) | 8(26.7) | 18(60.0) | 11(36.7)ab | 19(60.0)ab | 14(46.7)ab | 13(43.3)a | 6(20.0)a |
χ2值 | 31.064 | 95.807 | 25.739 | 6.847 | 32.083 | 33.363 | 75.553 | 28.207 | 39.783 | 14.046 | |
P值 | <0.001 | <0.001 | <0.001 | 0.033 | <0.001 | <0.001 | <0.001 | <0.001 | <0.001 | 0.001 |
自变量 | β | SE | Wald χ2值 | P值 | OR值 | 95%CI |
---|---|---|---|---|---|---|
卵巢肿瘤最大径≥10 cm | 0.666 | 0.307 | 4.704 | 0.030 | 1.947 | (1.066,3.556) |
肿瘤内有实性成分 | 2.289 | 0.404 | 32.045 | <0.001 | 9.862 | (4.465,21.782) |
肿瘤内有乳头 | 0.842 | 0.381 | 4.887 | 0.027 | 2.320 | (1.100,4.893) |
肿瘤内有血流信号 | 0.828 | 0.372 | 4.954 | 0.026 | 2.289 | (1.104,4.747) |
肿瘤表现为多房 | 1.744 | 0.324 | 29.053 | <0.001 | 5.722 | (3.034,10.789) |
CA125≥35.0 U/mL | 1.460 | 0.401 | 13.261 | <0.001 | 4.307 | (1.963,9.452) |
CA199≥39.0 U/mL | 0.801 | 0.394 | 4.138 | 0.042 | 2.227 | (1.030,4.816) |
Table 3 Multivariate Logistic regression analysis of the risk factors of malignant transformation of MOTs
自变量 | β | SE | Wald χ2值 | P值 | OR值 | 95%CI |
---|---|---|---|---|---|---|
卵巢肿瘤最大径≥10 cm | 0.666 | 0.307 | 4.704 | 0.030 | 1.947 | (1.066,3.556) |
肿瘤内有实性成分 | 2.289 | 0.404 | 32.045 | <0.001 | 9.862 | (4.465,21.782) |
肿瘤内有乳头 | 0.842 | 0.381 | 4.887 | 0.027 | 2.320 | (1.100,4.893) |
肿瘤内有血流信号 | 0.828 | 0.372 | 4.954 | 0.026 | 2.289 | (1.104,4.747) |
肿瘤表现为多房 | 1.744 | 0.324 | 29.053 | <0.001 | 5.722 | (3.034,10.789) |
CA125≥35.0 U/mL | 1.460 | 0.401 | 13.261 | <0.001 | 4.307 | (1.963,9.452) |
CA199≥39.0 U/mL | 0.801 | 0.394 | 4.138 | 0.042 | 2.227 | (1.030,4.816) |
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