Revascularization in Renal Artery Stenosis: Current Treatments and Outlook

doi:10.12114/j.issn.1007-9572.2022.0507

Abstract

Abstract:

Renal artery stenosis (RAS) refers to the reduction of lumen diameter of one or both renal arteries, which can cause multiple systemic lesions such as renovascular hypertension, ischemic nephropathy and flash pulmonary oedema. RAS has been attached importance with the improvement of diagnostic level. However, there are still no precise treatments for RAS. As for revascularization, its effect on RAS needs to be evaluated further, and it is also a hot research area. We analyzed the causes and mechanisms regarding the suboptimal effect of renal artery revascularization in some studies, summarized the strategies and neoadjuvant therapies that recently used to improve the effect of renal artery revascularization, with highlights on the importance of selection of patients for the treatment, providing evidence for guiding renal artery revascularization, and for choosing directions in research on patient selection for the treatment and the improvement of treatment effectiveness.

Key words: Renal artery, Renal artery stenosis, Percutaneous renal angioplasty, Renal artery revascularization, Review

摘要：

肾动脉狭窄（RAS）为一侧或双侧肾动脉管腔直径减小，可引起肾血管性高血压、缺血性肾病、闪烁性肺水肿等多个系统病变，随诊断水平的提高其越来越受到重视。近年来对于RAS的治疗方法仍不甚明确，血运重建效果有待考量且为相关学科研究热点。本文分析了血运重建在部分研究中效果欠佳的原因和机制，归纳了近年来改善血运重建效果不佳的策略及该领域的新兴辅助治疗方法，强调了患者筛选的重要性，旨在为肾动脉血运重建治疗提供更多的参考资料，为未来临床患者的筛选及治疗有效性的提高提供未来可研究的方向。

关键词: 肾动脉, 肾动脉狭窄, 经皮腔内肾血管成形术, 经皮肾血管重建术, 综述

MENG Yaqi,LIU Yanyang,TIAN Haiping, et al. Revascularization in Renal Artery Stenosis: Current Treatments and Outlook[J]. Chinese General Practice, 2023, 26(11): 1404-1410. DOI: 10.12114/j.issn.1007-9572.2022.0507.
孟雅琪,刘艳阳,田海萍等. 肾动脉狭窄血运重建的治疗现状及发展趋势[J]. 中国全科医学, 2023, 26(11): 1404-1410. DOI: 10.12114/j.issn.1007-9572.2022.0507.

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