Chinese General Practice ›› 2022, Vol. 25 ›› Issue (27): 3414-3421.DOI: 10.12114/j.issn.1007-9572.2022.0317
Special Issue: 睡眠问题专题研究
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Received:
2022-06-07
Revised:
2022-06-24
Published:
2022-09-20
Online:
2022-07-14
Contact:
Peipei WANG
About author:
通讯作者:
王配配
作者简介:
基金资助:
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URL: https://www.chinagp.net/EN/10.12114/j.issn.1007-9572.2022.0317
项目 | 接受滴定组(n=157) | 拒绝滴定组(n=245) | 检验统计量值 | P值 | |
---|---|---|---|---|---|
年龄〔n(%)〕 | -0.61c | 0.542 | |||
青年组(18~44岁) | 55(35.0) | 87(35.5) | |||
中年组(45~59岁) | 63(40.1) | 83(33.9) | |||
老年组(≥60岁) | 39(24.9) | 75(30.6) | |||
性别〔n(%)〕 | 0.54a | 0.463 | |||
男 | 118(75.2) | 176(71.8) | |||
女 | 39(24.8) | 69(28.2) | |||
民族〔n(%)〕 | 0.15b | 0.697 | |||
汉族 | 155(98.7) | 244(99.6) | |||
少数民族 | 2(1.3) | 1(0.4) | |||
文化程度〔n(%)〕 | 4.37a | 0.113 | |||
小学及以下 | 54(34.4) | 62(25.3) | |||
初中-高中 | 62(39.5) | 102(41.6) | |||
大学及以上 | 41(26.1) | 81(33.1) | |||
合并症〔n(%)〕 | 27(17.2) | 43(17.6) | 0.01a | 0.927 | |
夜间失眠易醒〔n(%)〕 | 66(42.0) | 112(45.7) | 0.52a | 0.469 | |
夜间憋醒〔n(%)〕 | 49(31.2) | 66(26.9) | 0.86a | 0.355 | |
日间嗜睡〔n(%)〕 | 77(49.0) | 108(44.1) | 0.95a | 0.330 | |
颈围〔M(P25,P75),㎝〕 | 40.0(37.0,42.0) | 39.0(37.0,41.0) | -0.94c | 0.347 | |
腹围〔M(P25,P75),㎝〕 | 95.0(88.5,102.0) | 94.0(89.0,101.0) | -0.22c | 0.825 | |
臀围〔M(P25,P75),㎝〕 | 101.0(97.0,105.5) | 97.0(97.0,105.0) | -0.42c | 0.674 | |
BMI〔M(P25,P75),kg/m2〕 | 26.2(23.2,28.9) | 25.8(23.8,29.2) | -0.25c | 0.807 | |
ESS〔M(P25,P75),分〕 | 9.0(5.0,12.0) | 7.0(4.0,12.0) | -1.64c | 0.101 | |
OSAHS严重程度〔n(%)〕 | -1.09c | 0.278 | |||
轻度 | 23(14.6) | 35(14.3) | |||
中度 | 48(30.6) | 93(38.0) | |||
重度 | 86(54.8) | 117(47.7) | |||
平均SPO2〔M(P25,P75),%〕 | 94.0(92.5,95.2) | 93.9(92.4,95.2) | -0.16c | 0.873 | |
LSPO2〔M(P25,P75),%〕 | 80.0(70.0,85.0) | 81.0(73.0,85.0) | -1.25c | 0.211 | |
T90〔M(P25,P75),/30min〕 | 0.6(0.1,2.0) | 0.4(0.1,1.9) | -0.97c | 0.332 |
Table 1 Comparison of demographic and clinical characteristics between acceptors and rejecters of NPPV titration
项目 | 接受滴定组(n=157) | 拒绝滴定组(n=245) | 检验统计量值 | P值 | |
---|---|---|---|---|---|
年龄〔n(%)〕 | -0.61c | 0.542 | |||
青年组(18~44岁) | 55(35.0) | 87(35.5) | |||
中年组(45~59岁) | 63(40.1) | 83(33.9) | |||
老年组(≥60岁) | 39(24.9) | 75(30.6) | |||
性别〔n(%)〕 | 0.54a | 0.463 | |||
男 | 118(75.2) | 176(71.8) | |||
女 | 39(24.8) | 69(28.2) | |||
民族〔n(%)〕 | 0.15b | 0.697 | |||
汉族 | 155(98.7) | 244(99.6) | |||
少数民族 | 2(1.3) | 1(0.4) | |||
文化程度〔n(%)〕 | 4.37a | 0.113 | |||
小学及以下 | 54(34.4) | 62(25.3) | |||
初中-高中 | 62(39.5) | 102(41.6) | |||
大学及以上 | 41(26.1) | 81(33.1) | |||
合并症〔n(%)〕 | 27(17.2) | 43(17.6) | 0.01a | 0.927 | |
夜间失眠易醒〔n(%)〕 | 66(42.0) | 112(45.7) | 0.52a | 0.469 | |
夜间憋醒〔n(%)〕 | 49(31.2) | 66(26.9) | 0.86a | 0.355 | |
日间嗜睡〔n(%)〕 | 77(49.0) | 108(44.1) | 0.95a | 0.330 | |
颈围〔M(P25,P75),㎝〕 | 40.0(37.0,42.0) | 39.0(37.0,41.0) | -0.94c | 0.347 | |
腹围〔M(P25,P75),㎝〕 | 95.0(88.5,102.0) | 94.0(89.0,101.0) | -0.22c | 0.825 | |
臀围〔M(P25,P75),㎝〕 | 101.0(97.0,105.5) | 97.0(97.0,105.0) | -0.42c | 0.674 | |
BMI〔M(P25,P75),kg/m2〕 | 26.2(23.2,28.9) | 25.8(23.8,29.2) | -0.25c | 0.807 | |
ESS〔M(P25,P75),分〕 | 9.0(5.0,12.0) | 7.0(4.0,12.0) | -1.64c | 0.101 | |
OSAHS严重程度〔n(%)〕 | -1.09c | 0.278 | |||
轻度 | 23(14.6) | 35(14.3) | |||
中度 | 48(30.6) | 93(38.0) | |||
重度 | 86(54.8) | 117(47.7) | |||
平均SPO2〔M(P25,P75),%〕 | 94.0(92.5,95.2) | 93.9(92.4,95.2) | -0.16c | 0.873 | |
LSPO2〔M(P25,P75),%〕 | 80.0(70.0,85.0) | 81.0(73.0,85.0) | -1.25c | 0.211 | |
T90〔M(P25,P75),/30min〕 | 0.6(0.1,2.0) | 0.4(0.1,1.9) | -0.97c | 0.332 |
影响因素 | β | SE | Wald χ2值 | OR(95%CI) | P值 | |
---|---|---|---|---|---|---|
常数项 | 0.762 | 1.228 | 0.385 | 2.142 | 0.535 | |
年龄〔以青年组(18~44岁)为参照〕 | ||||||
中年组(45~59岁) | 0.200 | 0.263 | 0.580 | 1.222(0.729,2.047) | 0.446 | |
老年组(≥60岁) | -0.210 | 0.296 | 0.502 | 0.811(0.454,1.448) | 0.479 | |
性别(以男性为参照) | ||||||
女性 | -0.038 | 0.274 | 0.020 | 0.962(0.562,1.648) | 0.889 | |
合并症(以否为参照) | ||||||
是 | 0.021 | 0.285 | 0.005 | 1.021(0.584,1.785) | 0.942 | |
夜间失眠易醒(以否为参照) | ||||||
是 | -0.163 | 0.230 | 0.505 | 0.849(0.542,1.332) | 0.477 | |
夜间憋醒(以否为参照) | ||||||
是 | -0.005 | 0.247 | 0.000 | 0.995(0.613,1.614) | 0.983 | |
日间嗜睡(以否为参照) | ||||||
是 | 0.054 | 0.230 | 0.054 | 1.055(0.672,1.658) | 0.816 | |
颈围 | -0.009 | 0.031 | 0.093 | 0.991(0.933,1.052) | 0.761 | |
BMI | -0.039 | 0.032 | 1.505 | 0.962(0.904,1.023) | 0.220 | |
ESS | 0.030 | 0.024 | 1.590 | 1.031(0.983,1.080) | 0.207 | |
OSAHS严重程度(以轻度为参照) | ||||||
中度 | -0.301 | 0.336 | 0.801 | 0.740(0.383,1.431) | 0.371 | |
重度 | -0.077 | 0.345 | 0.050 | 0.926(0.471,1.819) | 0.823 | |
T90 | 0.067 | 0.053 | 1.606 | 1.070(0.964,1.187) | 0.205 |
Table 2 Multivariate Logistic regression analysis of factors associated with NPPV titration acceptance
影响因素 | β | SE | Wald χ2值 | OR(95%CI) | P值 | |
---|---|---|---|---|---|---|
常数项 | 0.762 | 1.228 | 0.385 | 2.142 | 0.535 | |
年龄〔以青年组(18~44岁)为参照〕 | ||||||
中年组(45~59岁) | 0.200 | 0.263 | 0.580 | 1.222(0.729,2.047) | 0.446 | |
老年组(≥60岁) | -0.210 | 0.296 | 0.502 | 0.811(0.454,1.448) | 0.479 | |
性别(以男性为参照) | ||||||
女性 | -0.038 | 0.274 | 0.020 | 0.962(0.562,1.648) | 0.889 | |
合并症(以否为参照) | ||||||
是 | 0.021 | 0.285 | 0.005 | 1.021(0.584,1.785) | 0.942 | |
夜间失眠易醒(以否为参照) | ||||||
是 | -0.163 | 0.230 | 0.505 | 0.849(0.542,1.332) | 0.477 | |
夜间憋醒(以否为参照) | ||||||
是 | -0.005 | 0.247 | 0.000 | 0.995(0.613,1.614) | 0.983 | |
日间嗜睡(以否为参照) | ||||||
是 | 0.054 | 0.230 | 0.054 | 1.055(0.672,1.658) | 0.816 | |
颈围 | -0.009 | 0.031 | 0.093 | 0.991(0.933,1.052) | 0.761 | |
BMI | -0.039 | 0.032 | 1.505 | 0.962(0.904,1.023) | 0.220 | |
ESS | 0.030 | 0.024 | 1.590 | 1.031(0.983,1.080) | 0.207 | |
OSAHS严重程度(以轻度为参照) | ||||||
中度 | -0.301 | 0.336 | 0.801 | 0.740(0.383,1.431) | 0.371 | |
重度 | -0.077 | 0.345 | 0.050 | 0.926(0.471,1.819) | 0.823 | |
T90 | 0.067 | 0.053 | 1.606 | 1.070(0.964,1.187) | 0.205 |
项目 | 接受治疗组(n=75) | 拒绝治疗组(n=327) | 检验统计量值 | P值 | |
---|---|---|---|---|---|
年龄〔n(%)〕 | -2.29c | 0.022 | |||
青年组(18~44岁) | 29(38.7) | 113(34.6) | |||
中年组(45~59岁) | 37(49.3) | 109(33.3) | |||
老年组(≥60岁) | 9(12.0) | 105(32.1) | |||
性别〔n(%)〕 | 0.83a | 0.363 | |||
男 | 58(77.3) | 236(72.2) | |||
女 | 17(22.7) | 91(27.8) | |||
民族〔n(%)〕 | 1.96b | 0.162 | |||
汉族 | 73(97.3) | 326(99.7) | |||
少数民族 | 2(2.7) | 1(0.3) | |||
文化程度〔n(%)〕 | 3.56a | 0.169 | |||
小学及以下 | 15(20.0) | 101(30.9) | |||
初中-高中 | 35(46.7) | 129(39.4) | |||
大学及以上 | 25(33.3) | 97(29.7) | |||
合并症〔n(%)〕 | 11(14.7) | 59(18.0) | 0.48a | 0.487 | |
夜间失眠易醒〔n(%)〕 | 30(40.0) | 148(45.3) | 0.68a | 0.408 | |
夜间憋醒〔n(%)〕 | 29(38.7) | 86(26.3) | 4.57a | 0.033 | |
日间嗜睡〔n(%)〕 | 38(50.7) | 147(45.0) | 0.80a | 0.371 | |
颈围〔M(P25,P75),㎝〕 | 40.0(37.0,42.0) | 39.0(37.0,41.0) | -0.97c | 0.330 | |
腹围〔M(P25,P75),㎝〕 | 97.0(89.0,103.0) | 94.0(89.0,101.0) | -1.23c | 0.210 | |
臀围〔M(P25,P75),㎝〕 | 101.0(98.0,106.0) | 101.0(97.0,105.0) | -0.62c | 0.538 | |
BMI〔M(P25,P75),kg/m2〕 | 26.6(24.0,29.3) | 25.8(23.6,29.0) | -1.01c | 0.313 | |
ESS〔M(P25,P75),分〕 | 10.0(6.0,12.0) | 8.0(5.0,12.0) | -1.56c | 0.119 | |
OSAHS严重程度〔n(%)〕 | -2.57c | 0.010 | |||
轻度 | 7(9.3) | 51(15.6) | |||
中度 | 20(26.7) | 121(37.0) | |||
重度 | 48(64.0) | 155(47.4) | |||
平均SPO2〔M(P25,P75),%〕 | 93.3(91.9,94.9) | 94.1(92.6,95.3) | -2.10c | 0.035 | |
LSPO2〔M(P25,P75),%〕 | 78.0(67.0,84.0) | 81.0(73.0,85.0) | -2.53c | 0.011 | |
T90〔M(P25,P75),/30 min〕 | 0.9(0.2,2.6) | 0.4(0.1,1.8) | -2.68c | 0.007 |
Table 3 Comparison of demographic and clinical characteristics between acceptors and rejecters of NPPV
项目 | 接受治疗组(n=75) | 拒绝治疗组(n=327) | 检验统计量值 | P值 | |
---|---|---|---|---|---|
年龄〔n(%)〕 | -2.29c | 0.022 | |||
青年组(18~44岁) | 29(38.7) | 113(34.6) | |||
中年组(45~59岁) | 37(49.3) | 109(33.3) | |||
老年组(≥60岁) | 9(12.0) | 105(32.1) | |||
性别〔n(%)〕 | 0.83a | 0.363 | |||
男 | 58(77.3) | 236(72.2) | |||
女 | 17(22.7) | 91(27.8) | |||
民族〔n(%)〕 | 1.96b | 0.162 | |||
汉族 | 73(97.3) | 326(99.7) | |||
少数民族 | 2(2.7) | 1(0.3) | |||
文化程度〔n(%)〕 | 3.56a | 0.169 | |||
小学及以下 | 15(20.0) | 101(30.9) | |||
初中-高中 | 35(46.7) | 129(39.4) | |||
大学及以上 | 25(33.3) | 97(29.7) | |||
合并症〔n(%)〕 | 11(14.7) | 59(18.0) | 0.48a | 0.487 | |
夜间失眠易醒〔n(%)〕 | 30(40.0) | 148(45.3) | 0.68a | 0.408 | |
夜间憋醒〔n(%)〕 | 29(38.7) | 86(26.3) | 4.57a | 0.033 | |
日间嗜睡〔n(%)〕 | 38(50.7) | 147(45.0) | 0.80a | 0.371 | |
颈围〔M(P25,P75),㎝〕 | 40.0(37.0,42.0) | 39.0(37.0,41.0) | -0.97c | 0.330 | |
腹围〔M(P25,P75),㎝〕 | 97.0(89.0,103.0) | 94.0(89.0,101.0) | -1.23c | 0.210 | |
臀围〔M(P25,P75),㎝〕 | 101.0(98.0,106.0) | 101.0(97.0,105.0) | -0.62c | 0.538 | |
BMI〔M(P25,P75),kg/m2〕 | 26.6(24.0,29.3) | 25.8(23.6,29.0) | -1.01c | 0.313 | |
ESS〔M(P25,P75),分〕 | 10.0(6.0,12.0) | 8.0(5.0,12.0) | -1.56c | 0.119 | |
OSAHS严重程度〔n(%)〕 | -2.57c | 0.010 | |||
轻度 | 7(9.3) | 51(15.6) | |||
中度 | 20(26.7) | 121(37.0) | |||
重度 | 48(64.0) | 155(47.4) | |||
平均SPO2〔M(P25,P75),%〕 | 93.3(91.9,94.9) | 94.1(92.6,95.3) | -2.10c | 0.035 | |
LSPO2〔M(P25,P75),%〕 | 78.0(67.0,84.0) | 81.0(73.0,85.0) | -2.53c | 0.011 | |
T90〔M(P25,P75),/30 min〕 | 0.9(0.2,2.6) | 0.4(0.1,1.8) | -2.68c | 0.007 |
影响因素 | β | SE | Wald χ2值 | OR(95%CI) | P值 | |
---|---|---|---|---|---|---|
常数项 | 0.118 | 1.915 | 0.004 | 1.125 | 0.951 | |
年龄〔以青年组(18~44岁)为参照〕 | ||||||
中年组(45~59岁) | 0.391 | 0.317 | 1.522 | 1.479(0.794,2.775) | 0.217 | |
老年组(≥60岁) | -0.947 | 0.444 | 4.545 | 0.388(0.162,0.926) | 0.033 | |
性别(以男性为参照) | ||||||
女性 | 0.055 | 0.393 | 0.020 | 1.056(0.489,2.282) | 0.889 | |
合并症(以否为参照) | ||||||
是 | -0.298 | 0.376 | 0.625 | 0.743(0.355,1.553) | 0.429 | |
夜间失眠易醒(以否为参照) | ||||||
是 | -0.146 | 0.298 | 0.240 | 0.864(0.482,1.549) | 0.624 | |
夜间憋醒(以否为参照) | ||||||
是 | 0.280 | 0.308 | 0.828 | 1.324(0.724,2.421) | 0.363 | |
日间嗜睡(以否为参照) | ||||||
是 | -0.022 | 0.300 | 0.005 | 0.978(0.543,1.762) | 0.942 | |
颈围 | -0.044 | 0.055 | 0.647 | 0.957(0.860,1.065) | 0.421 | |
BMI | -0.012 | 0.042 | 0.080 | 0.988(0.909,1.074) | 0.778 | |
ESS | 0.002 | 0.031 | 0.005 | 1.002(0.942,1.066) | 0.946 | |
OSAHS严重程度(以轻度为参照) | ||||||
中度 | 0.018 | 0.489 | 0.001 | 1.018(0.390,2.656) | 0.971 | |
重度 | 0.452 | 0.493 | 0.842 | 1.572(0.598,4.130) | 0.359 | |
T90 | 0.134 | 0.062 | 4.693 | 1.143(1.013,1.291) | 0.030 |
Table 4 Multivariate Logistic regression analysis of factors associated with NPPV acceptance
影响因素 | β | SE | Wald χ2值 | OR(95%CI) | P值 | |
---|---|---|---|---|---|---|
常数项 | 0.118 | 1.915 | 0.004 | 1.125 | 0.951 | |
年龄〔以青年组(18~44岁)为参照〕 | ||||||
中年组(45~59岁) | 0.391 | 0.317 | 1.522 | 1.479(0.794,2.775) | 0.217 | |
老年组(≥60岁) | -0.947 | 0.444 | 4.545 | 0.388(0.162,0.926) | 0.033 | |
性别(以男性为参照) | ||||||
女性 | 0.055 | 0.393 | 0.020 | 1.056(0.489,2.282) | 0.889 | |
合并症(以否为参照) | ||||||
是 | -0.298 | 0.376 | 0.625 | 0.743(0.355,1.553) | 0.429 | |
夜间失眠易醒(以否为参照) | ||||||
是 | -0.146 | 0.298 | 0.240 | 0.864(0.482,1.549) | 0.624 | |
夜间憋醒(以否为参照) | ||||||
是 | 0.280 | 0.308 | 0.828 | 1.324(0.724,2.421) | 0.363 | |
日间嗜睡(以否为参照) | ||||||
是 | -0.022 | 0.300 | 0.005 | 0.978(0.543,1.762) | 0.942 | |
颈围 | -0.044 | 0.055 | 0.647 | 0.957(0.860,1.065) | 0.421 | |
BMI | -0.012 | 0.042 | 0.080 | 0.988(0.909,1.074) | 0.778 | |
ESS | 0.002 | 0.031 | 0.005 | 1.002(0.942,1.066) | 0.946 | |
OSAHS严重程度(以轻度为参照) | ||||||
中度 | 0.018 | 0.489 | 0.001 | 1.018(0.390,2.656) | 0.971 | |
重度 | 0.452 | 0.493 | 0.842 | 1.572(0.598,4.130) | 0.359 | |
T90 | 0.134 | 0.062 | 4.693 | 1.143(1.013,1.291) | 0.030 |
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