Chinese General Practice ›› 2023, Vol. 26 ›› Issue (06): 659-664.DOI: 10.12114/j.issn.1007-9572.2022.0564
Special Issue: 心血管最新文章合集
• Original Research • Previous Articles Next Articles
Received:
2022-07-05
Revised:
2022-09-02
Published:
2023-02-20
Online:
2022-09-22
Contact:
ZHANG Jing
About author:
通讯作者:
张晶
作者简介:
基金资助:
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URL: https://www.chinagp.net/EN/10.12114/j.issn.1007-9572.2022.0564
组别 | 例数 | 男性〔n(%)〕 | 年龄〔M(P25,P75),岁〕 | 吸烟史〔n(%)〕 | 饮酒史〔n(%)〕 | 高血压史〔n(%)〕 | 糖尿病史〔n(%)〕 | BMI〔M(P25,P75),kg/m2〕 |
---|---|---|---|---|---|---|---|---|
非AMI组 | 574 | 362(63.07) | 37.0(33.0,41.0) | 218(37.98) | 114(19.86) | 232(40.42) | 108(18.82) | 24.6(21.6,27.9) |
AMI组 | 627 | 468(74.64) | 37.0(33.2,41.0) | 404(64.43) | 153(24.40) | 299(47.69) | 138(22.01) | 24.0(21.6,27.4) |
Z(χ2)值 | 18.807a | -0.471 | 83.996a | 3.575a | 6.420a | 1.877a | -1.224 | |
P值 | <0.001 | 0.638 | <0.001 | 0.059 | 0.011 | 0.171 | 0.221 | |
组别 | TG〔M(P25,P75),mmol/L〕 | TC〔M(P25,P75),mmol/L〕 | HDL-C〔M(P25,P75),mmol/L〕 | LDL-C〔M(P25,P75),mmol/L〕 | RLP-C〔M(P25,P75),mmol/L〕 | AIP〔M(P25,P75)〕 | ||
非AMI组 | 1.28(1.02,1.90) | 4.10(3.55,4.75) | 1.20(1.00,1.40) | 2.40(1.95,2.93) | 0.40(0.24,0.59) | 0.04(-0.09,0.22) | ||
AMI组 | 1.94(1.43,2.92) | 4.50(3.81,5.34) | 0.85(0.73,1.00) | 2.69(2.11,3.36) | 0.85(0.63,1.20) | 0.36(0.20,0.56) | ||
Z(χ2)值 | -13.083 | -7.098 | -21.306 | -5.293 | -21.044 | -18.746 | ||
P值 | <0.001 | <0.001 | <0.001 | <0.001 | <0.001 | <0.001 |
Table 1 Comparison of general data and serum lipid levels between young coronary heart disease patients with and without first-time acute myocardial infarction
组别 | 例数 | 男性〔n(%)〕 | 年龄〔M(P25,P75),岁〕 | 吸烟史〔n(%)〕 | 饮酒史〔n(%)〕 | 高血压史〔n(%)〕 | 糖尿病史〔n(%)〕 | BMI〔M(P25,P75),kg/m2〕 |
---|---|---|---|---|---|---|---|---|
非AMI组 | 574 | 362(63.07) | 37.0(33.0,41.0) | 218(37.98) | 114(19.86) | 232(40.42) | 108(18.82) | 24.6(21.6,27.9) |
AMI组 | 627 | 468(74.64) | 37.0(33.2,41.0) | 404(64.43) | 153(24.40) | 299(47.69) | 138(22.01) | 24.0(21.6,27.4) |
Z(χ2)值 | 18.807a | -0.471 | 83.996a | 3.575a | 6.420a | 1.877a | -1.224 | |
P值 | <0.001 | 0.638 | <0.001 | 0.059 | 0.011 | 0.171 | 0.221 | |
组别 | TG〔M(P25,P75),mmol/L〕 | TC〔M(P25,P75),mmol/L〕 | HDL-C〔M(P25,P75),mmol/L〕 | LDL-C〔M(P25,P75),mmol/L〕 | RLP-C〔M(P25,P75),mmol/L〕 | AIP〔M(P25,P75)〕 | ||
非AMI组 | 1.28(1.02,1.90) | 4.10(3.55,4.75) | 1.20(1.00,1.40) | 2.40(1.95,2.93) | 0.40(0.24,0.59) | 0.04(-0.09,0.22) | ||
AMI组 | 1.94(1.43,2.92) | 4.50(3.81,5.34) | 0.85(0.73,1.00) | 2.69(2.11,3.36) | 0.85(0.63,1.20) | 0.36(0.20,0.56) | ||
Z(χ2)值 | -13.083 | -7.098 | -21.306 | -5.293 | -21.044 | -18.746 | ||
P值 | <0.001 | <0.001 | <0.001 | <0.001 | <0.001 | <0.001 |
变量 | β | SE | Wald χ2值 | P值 | OR(95%CI) |
---|---|---|---|---|---|
男性 | 0.545 | 0.126 | 18.641 | <0.001 | 1.724(1.346,2.207) |
高血压史 | 0.296 | 0.117 | 6.408 | 0.011 | 1.344(1.069,1.689) |
吸烟史 | 1.085 | 0.120 | 81.955 | <0.001 | 2.958(2.339,3.742) |
TG≥1.7 mmol/L | 1.342 | 0.123 | 119.309 | <0.001 | 3.826(3.007,4.868) |
TC≥5.17 mmol/L | 1.101 | 0.153 | 51.725 | <0.001 | 3.009(2.228,4.062) |
HDL-C≥1.19 mmol/L | -3.670 | 0.303 | 146.345 | <0.001 | 0.025(0.014,0.046) |
LDL-C≥3.37 mmol/L | 0.790 | 0.155 | 26.153 | <0.001 | 2.204(1.628,2.983) |
RLP-C≥0.6 mmol/L | 2.240 | 0.138 | 262.122 | <0.001 | 9.389(7.159,12.313) |
AIP≥0.2 | 2.135 | 0.132 | 260.196 | <0.001 | 8.458(6.525,10.963) |
Table 2 Univariate Logistic regression analysis of factors associated with first-time acute myocardial infarction in young adults with coronary heart disease
变量 | β | SE | Wald χ2值 | P值 | OR(95%CI) |
---|---|---|---|---|---|
男性 | 0.545 | 0.126 | 18.641 | <0.001 | 1.724(1.346,2.207) |
高血压史 | 0.296 | 0.117 | 6.408 | 0.011 | 1.344(1.069,1.689) |
吸烟史 | 1.085 | 0.120 | 81.955 | <0.001 | 2.958(2.339,3.742) |
TG≥1.7 mmol/L | 1.342 | 0.123 | 119.309 | <0.001 | 3.826(3.007,4.868) |
TC≥5.17 mmol/L | 1.101 | 0.153 | 51.725 | <0.001 | 3.009(2.228,4.062) |
HDL-C≥1.19 mmol/L | -3.670 | 0.303 | 146.345 | <0.001 | 0.025(0.014,0.046) |
LDL-C≥3.37 mmol/L | 0.790 | 0.155 | 26.153 | <0.001 | 2.204(1.628,2.983) |
RLP-C≥0.6 mmol/L | 2.240 | 0.138 | 262.122 | <0.001 | 9.389(7.159,12.313) |
AIP≥0.2 | 2.135 | 0.132 | 260.196 | <0.001 | 8.458(6.525,10.963) |
变量 | β | SE | Wald χ2值 | P值 | OR(95%CI) |
---|---|---|---|---|---|
吸烟史 | 0.932 | 0.169 | 30.453 | <0.001 | 2.541(1.824,3.538) |
TC≥5.17 mmol/L | 1.025 | 0.350 | 8.593 | 0.003 | 2.787(1.405,5.531) |
HDL-C≥1.19 mmol/L | -3.024 | 0.329 | 84.390 | <0.001 | 0.049(0.025,0.093) |
RLP-C≥0.6 mmol/L | 1.331 | 0.182 | 53.293 | <0.001 | 3.786(2.648,5.413) |
AIP≥0.2 | 1.232 | 0.248 | 24.592 | <0.001 | 3.427(2.106,5.576) |
Table 3 Multivariate Logistic regression analysis of factors associated with first-time acute myocardial infarction in young adults with coronary heart disease
变量 | β | SE | Wald χ2值 | P值 | OR(95%CI) |
---|---|---|---|---|---|
吸烟史 | 0.932 | 0.169 | 30.453 | <0.001 | 2.541(1.824,3.538) |
TC≥5.17 mmol/L | 1.025 | 0.350 | 8.593 | 0.003 | 2.787(1.405,5.531) |
HDL-C≥1.19 mmol/L | -3.024 | 0.329 | 84.390 | <0.001 | 0.049(0.025,0.093) |
RLP-C≥0.6 mmol/L | 1.331 | 0.182 | 53.293 | <0.001 | 3.786(2.648,5.413) |
AIP≥0.2 | 1.232 | 0.248 | 24.592 | <0.001 | 3.427(2.106,5.576) |
指标 | 约登指数 | AUC(95%CI) | 灵敏度 | 特异度 | 最佳截断值 | P值 |
---|---|---|---|---|---|---|
RLP-C | 0.547 | 0.851(0.830,0.873) | 0.848 | 0.699 | 0.535 mmol/L | <0.001 |
AIP | 0.544 | 0.813(0.789,0.837) | 0.852 | 0.660 | 0.122 | <0.001 |
Table 4 Comparison of AUC,sensitivity and specificity of RLP-C and AIP in predicting first-time acute myocardial infarction in young adults with coronary heart disease
指标 | 约登指数 | AUC(95%CI) | 灵敏度 | 特异度 | 最佳截断值 | P值 |
---|---|---|---|---|---|---|
RLP-C | 0.547 | 0.851(0.830,0.873) | 0.848 | 0.699 | 0.535 mmol/L | <0.001 |
AIP | 0.544 | 0.813(0.789,0.837) | 0.852 | 0.660 | 0.122 | <0.001 |
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