Chinese General Practice ›› 2022, Vol. 25 ›› Issue (09): 1123-1129.DOI: 10.12114/j.issn.1007-9572.2021.02.079
Special Issue: 神经系统疾病最新文章合集; 精神卫生最新文章合集
• Article·Brain Health • Previous Articles Next Articles
Brain White Matter Fiber Bundle Alterations and Severity of Depression in Patients with Post-stroke Depression
1.Department of Neurology,the First Affiliated Hospital of Jinzhou Medical University,Jinzhou 121000,China
2.Nursing School,Jinzhou Medical University,Jinzhou 121000,China
*Corresponding author:SUI Rubo,Professor,Chief physician;E-mail:srb7246@163.com
Received:
2021-08-16
Revised:
2021-11-29
Published:
2022-03-20
Online:
2022-03-01
通讯作者:
隋汝波
基金资助:
CLC Number:
QI Jie, ZHANG Lei, DENG Lijun, DUAN Xiaodi, DONG Binbin, SUI Rubo.
Brain White Matter Fiber Bundle Alterations and Severity of Depression in Patients with Post-stroke Depression [J]. Chinese General Practice, 2022, 25(09): 1123-1129.
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URL: https://www.chinagp.net/EN/10.12114/j.issn.1007-9572.2021.02.079
组别 | 例数 | 性别(男/女) | 年龄(±s,岁) | 受教育年限(±s,年) | 冠心病〔n(%)〕 | LDL(±s,mmol/L) | HDL(±s,mmol/L) | 血糖(±s,mmol/L) | NIHSS评分(±s,分) |
---|---|---|---|---|---|---|---|---|---|
正常对照组 | 20 | 10/10 | 53.8±8.4 | 9.3±3.2 | 10(50.0) | 3.06±1.12 | 1.13±0.34 | 7.4±1.7 | - |
非PSD组 | 20 | 10/10 | 55.1±8.8 | 8.8±3.2 | 10(50.0) | 3.11±1.01 | 1.28±0.32 | 7.4±1.8 | 6.8±3.0 |
PSD组 | 20 | 10/10 | 54.6±7.5 | 9.1±3.2 | 9(45.0) | 3.03±1.06 | 1.20±0.24 | 7.4±2.1 | 6.9±4.3 |
检验统计量值 | 0a | 0.182 | 0.130 | 0.133 | 0.033 | 1.138 | 0.012 | 0.016b | |
P值 | 1.00 | 0.83 | 0.88 | 0.94 | 0.97 | 0.33 | 0.99 | 0.90 |
Table 1 Comparison of general information among first-episode ischemic stroke inpatients with and without post-stroke depression,and healthy physical examinees
组别 | 例数 | 性别(男/女) | 年龄(±s,岁) | 受教育年限(±s,年) | 冠心病〔n(%)〕 | LDL(±s,mmol/L) | HDL(±s,mmol/L) | 血糖(±s,mmol/L) | NIHSS评分(±s,分) |
---|---|---|---|---|---|---|---|---|---|
正常对照组 | 20 | 10/10 | 53.8±8.4 | 9.3±3.2 | 10(50.0) | 3.06±1.12 | 1.13±0.34 | 7.4±1.7 | - |
非PSD组 | 20 | 10/10 | 55.1±8.8 | 8.8±3.2 | 10(50.0) | 3.11±1.01 | 1.28±0.32 | 7.4±1.8 | 6.8±3.0 |
PSD组 | 20 | 10/10 | 54.6±7.5 | 9.1±3.2 | 9(45.0) | 3.03±1.06 | 1.20±0.24 | 7.4±2.1 | 6.9±4.3 |
检验统计量值 | 0a | 0.182 | 0.130 | 0.133 | 0.033 | 1.138 | 0.012 | 0.016b | |
P值 | 1.00 | 0.83 | 0.88 | 0.94 | 0.97 | 0.33 | 0.99 | 0.90 |
组别 | 例数 | SDS标准分 | HAMD-24评分 |
---|---|---|---|
正常对照组 | 20 | 26.80±7.47a | 2.45±1.50a |
非PSD组 | 20 | 29.20±10.74a | 2.60±1.39a |
PSD组 | 20 | 57.85±5.04 | 17.65±4.37 |
F值 | 92.085 | 194.912 | |
P值 | <0.01 | <0.01 |
Table 2 Comparison of standard score of SDS and HAMD-24 score among first-episode ischemic stroke inpatients with and without post-stroke depression,and healthy physical examinees
组别 | 例数 | SDS标准分 | HAMD-24评分 |
---|---|---|---|
正常对照组 | 20 | 26.80±7.47a | 2.45±1.50a |
非PSD组 | 20 | 29.20±10.74a | 2.60±1.39a |
PSD组 | 20 | 57.85±5.04 | 17.65±4.37 |
F值 | 92.085 | 194.912 | |
P值 | <0.01 | <0.01 |
组别 | 例数 | 下额枕束 | 皮质脊髓束 | ||||||
---|---|---|---|---|---|---|---|---|---|
病灶侧 | 病灶对侧 | t配对值 | P值 | 病灶侧 | 病灶对侧 | t配对值 | P值 | ||
正常对照组 | 20 | 0.574±0.059a | 0.583±0.067 | 1.156 | 0.26 | 0.575±0.049a | 0.573±0.052 | 0.322 | 0.75 |
非PSD组 | 20 | 0.575±0.047a | 0.578±0.049 | 0.993 | 0.33 | 0.565±0.033a | 0.571±0.039 | 1.602 | 0.13 |
PSD组 | 20 | 0.475±0.055 | 0.572±0.071 | -8.622 | <0.01 | 0.459±0.038 | 0.576±0.077 | -6.153 | <0.01 |
F(χ2)值 | 22.868 | 0.165 | 50.404 | 0.035 | |||||
P值 | <0.01 | 0.85 | <0.01 | 0.97 |
Table 3 Comparison of fractional anisotropy in regions of interest among first-episode ischemic stroke inpatients with and without post-stroke depression,and healthy physical examinees
组别 | 例数 | 下额枕束 | 皮质脊髓束 | ||||||
---|---|---|---|---|---|---|---|---|---|
病灶侧 | 病灶对侧 | t配对值 | P值 | 病灶侧 | 病灶对侧 | t配对值 | P值 | ||
正常对照组 | 20 | 0.574±0.059a | 0.583±0.067 | 1.156 | 0.26 | 0.575±0.049a | 0.573±0.052 | 0.322 | 0.75 |
非PSD组 | 20 | 0.575±0.047a | 0.578±0.049 | 0.993 | 0.33 | 0.565±0.033a | 0.571±0.039 | 1.602 | 0.13 |
PSD组 | 20 | 0.475±0.055 | 0.572±0.071 | -8.622 | <0.01 | 0.459±0.038 | 0.576±0.077 | -6.153 | <0.01 |
F(χ2)值 | 22.868 | 0.165 | 50.404 | 0.035 | |||||
P值 | <0.01 | 0.85 | <0.01 | 0.97 |
组别 | 例数 | 下额枕束 | 皮质脊髓束 | ||||||
---|---|---|---|---|---|---|---|---|---|
病灶侧 | 病灶对侧 | t配对值 | P值 | 病灶侧 | 病灶对侧 | t配对值 | P值 | ||
正常对照组 | 20 | 1 235.90±207.09a | 1 246.95±213.17 | 1.381 | 0.18 | 1 348.85±152.50a | 1 376.65±108.78 | 1.391 | 0.18 |
非PSD组 | 20 | 1 162.00±217.06a | 1 173.25±219.02 | 1.093 | 0.29 | 1 347.15±218.66a | 1 357.15±215.53 | 1.900 | 0.07 |
PSD组 | 20 | 888.75±144.07 | 1 297.40±157.94 | 10.812 | <0.01 | 946.15±210.66 | 1 379.65±152.42 | 8.270 | <0.01 |
F(χ2)值 | 18.115 | 1.976 | 27.976 | 0.110 | |||||
P值 | <0.01 | 0.15 | <0.01 | 0.90 |
Table 4 Comparison of number of fiber bundles in regions of interest among first-episode ischemic stroke inpatients with and without post-stroke depression,and healthy physical examinees
组别 | 例数 | 下额枕束 | 皮质脊髓束 | ||||||
---|---|---|---|---|---|---|---|---|---|
病灶侧 | 病灶对侧 | t配对值 | P值 | 病灶侧 | 病灶对侧 | t配对值 | P值 | ||
正常对照组 | 20 | 1 235.90±207.09a | 1 246.95±213.17 | 1.381 | 0.18 | 1 348.85±152.50a | 1 376.65±108.78 | 1.391 | 0.18 |
非PSD组 | 20 | 1 162.00±217.06a | 1 173.25±219.02 | 1.093 | 0.29 | 1 347.15±218.66a | 1 357.15±215.53 | 1.900 | 0.07 |
PSD组 | 20 | 888.75±144.07 | 1 297.40±157.94 | 10.812 | <0.01 | 946.15±210.66 | 1 379.65±152.42 | 8.270 | <0.01 |
F(χ2)值 | 18.115 | 1.976 | 27.976 | 0.110 | |||||
P值 | <0.01 | 0.15 | <0.01 | 0.90 |
Figure 1 Correlation of fiber bundles on the side of stroke with HAMD-24 score in first-episode ischemic stroke inpatients with post-stroke depression
Figure 2 Correlation between number of fiber bundles on the side of stroke and HAMD-24 score in first-episode ischemic stroke inpatients with post-stroke depression
Figure 3 Diffusion tensor tractography imaging of inferior fronto-occipital fasciculus of a first-episode ischemic stroke inpatient with post-stroke depression
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