Chinese General Practice ›› 2020, Vol. 23 ›› Issue (18): 2270-2274.DOI: 10.12114/j.issn.1007-9572.2020.00.248

• Monographic Research • Previous Articles     Next Articles

Efficacy of Enhanced External Counterpulsation in Patients with Coronary Heart Disease Complicated with Cardiac Dysfunction during the Cardiac Rehabilitation Training 

  

  1. Cardiovascular Department,the Second Affiliated Hospital of Zhengzhou University,Zhengzhou 450014,China
    *Corresponding author:ZHANG Hui,Chief physician;E-mail:zzzjs@163.com
  • Published:2020-06-20 Online:2020-06-20

增强型体外反搏在冠心病合并心功能不全患者心脏康复训练治疗中的应用价值研究

  

  1. 450014河南省郑州市,郑州大学第二附属医院心血管内科
    *通信作者:张辉,主任医师;E-mail:zzzjs@163.com
  • 基金资助:
    基金项目:河南省医学科技攻关计划普通项目(201303088);河南省医学科技攻关计划省部共建项目(201601008)

Abstract: Background In recent years,a large number of studies at home and abroad on the enhanced external counterpulsation(EECP),a type of "passive" exercise,have shown that EECP can improve exercise tolerance and cardiac function in patients with stable and unstable angina pectoris and mild to moderate cardiac insufficiency.Yet few reports have covered whether additional gain can be achieved in EECP in combination with active exercises like cardiac rehabilitation training.Objective To explore the efficacy of EECP in cardiac rehabilitation for patients with coronary heart disease and cardiac dysfunction.Methods A total of 100 patients with coronary heart disease and cardiac insufficiency who were hospitalized in Cardiovascular Department,the Second Affiliated Hospital of Zhengzhou University from March 2018 to April 2019 were recruited voluntarily.They were randomly and equally divided into two groups,namely,the control group(receiving conventional medication+cardiac rehabilitation training)and the counterpulsation group(receiving conventional medication+cardiac rehabilitation training+EECP)with the adoption of random number tables.Then,the anaerobic threshold(AT),6-minute walking distance(6MWD),left ventricular ejection fraction(LVEF),and serum brain natriuretic peptide(BNP)before and after treatment in the two groups were measured and recorded.Results The counterpulsation group,after the treatment,had higher mean levels of AT,6MWD and LVEF,and lower mean level of BNP than the control group(P<0.05).Both groups had significantly increased mean levels of AT,6MWD,and LVEF,as well as significantly lowered mean level of BNP after treatment(P<0.05).Conclusion EECP may significantly enhance exercise tolerance,6MWD,heart pump function and heart failure related indices in patients with coronary heart disease and cardiac insufficiency and cardiac rehabilitation training.Its efficacy is better than that of medication treatment or cardiac rehabilitation training alone.Therefore,EECP is highly worthy of clinical promotion.

Key words: Coronary disease, Cardiac dysfunction, Enhanced external counterpulsation, Cardiac rehabilitation, Treatment outcome

摘要: 背景 增强型体外反搏(EECP)是一种“被动”运动,近年来国内外大量研究表明EECP可改善稳定型心绞痛及不稳定型心绞痛、轻中度心功能不全患者的运动耐量及心功能。而心脏康复训练是主动运动,二者联合治疗是否可使患者额外增益,目前还鲜有报道。目的 探讨EECP在冠心病合并心功能不全患者心脏康复训练治疗中的应用价值。方法 选取2018年3月—2019年4月在郑州大学第二附属医院心血管内科住院的自愿参与本研究的冠心病合并心功能不全患者100例为研究对象。采用随机数字表法将患者分为对照组(接受常规药物治疗+心脏康复训练)和反搏组(接受常规药物治疗+心脏康复训练+EECP治疗),各50例。观察两组患者治疗前、后无氧阈值(AT)、6 min步行距离(6MWD)、左心室射血分数(LVEF)及血清脑钠肽(BNP)。结果 反搏组治疗后AT、6MWD、LVEF大于对照组,BNP低于对照组(P<0.05)。对照组、反搏组治疗后AT、6MWD、LVEF均大于本组治疗前,BNP均低于本组治疗前(P<0.05)。结论 EECP能够明显改善已接受心脏康复训练的冠心病合并心功能不全患者的运动耐量、步行距离、心脏泵功能及心力衰竭相关指标,效果优于单纯应用药物及心脏康复训练治疗,值得临床推广。

关键词: 冠心病, 心功能不全, 增强型体外反搏, 心脏康复, 治疗结果