中国全科医学 ›› 2021, Vol. 24 ›› Issue (30): 3905-3908.DOI: 10.12114/j.issn.1007-9572.2021.00.453

• 专题研究 • 上一篇    

车祸复合伤并低钠血症致可逆性后部白质脑病综合征一例报道并文献复习

毛振林,杨灿洪*,蔡梓博,谢文艺,吕田明   

  1. 510630 广东省广州市,南方医科大学第三附属医院神经内科
    *通信作者:杨灿洪,主治医师;E-mail:daocaorenych@163.com
  • 出版日期:2021-10-20 发布日期:2021-10-20
  • 基金资助:
    广东省医学科学技术研究项目(A2018061);广州市科技计划项目(201803010010);南方医科大学第三附属医院青年科研启动项目(2019Q014)

Reversible Posterior Leukoencephalopathy Syndrome Due to Hyponatremia and Combined Injuries Caused by a Traffic Accident:a Case Report and Literature Review 

MAO Zhenlin,YANG Canhong*,CAI Zibo,XIE Wenyi,LYU Tianming   

  1. Department of Neurology,the Third Affiliated Hospital of Southern Medical University,Guangzhou 510630,China
    *Corresponding author:YANG Canhong,Attending physician;E-mail:daocaorenych@163.com
  • Published:2021-10-20 Online:2021-10-20

摘要: 可逆性后部白质脑病综合征(RPLS)是一组临床少见的急性或亚急性起病的神经影像学综合征,主要临床表现包括头痛、头晕、恶心、呕吐、癫痫发作、视觉障碍、意识障碍及精神行为异常等,典型影像学表现为可逆的对称性大脑后部白质病变。本文报道了1例车祸复合伤并低钠血症所致RPLS患者,并进行了文献复习,提示低钠血症是导致RPLS的少见原因。临床上遇到各种原因导致的低钠血症患者时应警惕RPLS的发生,而RPLS通常是可逆的,早期识别和治疗对防止永久性神经系统后遗症的发生至关重要。

关键词: 可逆性后部白质脑病综合征, 多处创伤, 低钠血症, 复合伤, 病例报告, 典型病例, 历史文献

Abstract: Reversible posterior leukoencephalopathy syndrom(RPLS),a group of rare neuroimaging syndrome with acute or subacute onset,mainly manifested as headache,dizziness,nausea,vomiting,seizure,visual abnormality,consciousness impairment and disturbance of mental behavior. The typical imaging fingdings of PRLS are reversible and symmetric lesions in white matter of the posterior brain areas. A case of RPLS caused by hyponatremia combined with traffic accident injuries was reported and related literatures were reviewed in this paper,indicating that hyponatremia may be a rare cause of RPLS. Therefore the occurrence of RPLS should be concerned when the hyponatremia caused by various reasons occurred in clinical practice,and early identification and treatment of are essential to prevent permanent neurological sequelae because of the reversibility of RPLS.

Key words: Reversible posterior leukoencephalopathy syndrome, Multiple trauma, Hyponatremia, Combined injuries, Case reports, Typical cases, Historical article