中国全科医学

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生活行为因素与抑郁症的关系:社区人群的横断面研究

赵紫淇, 刘明月, 王楠, 罗政豪, 陈新洋, 李峥, 张尚明珠, 张皓若, 陈嘉琦, 郑一展, 武建辉, 张秀军   

  1. 华北理工大学, 中国
    河北省煤矿卫生与安全重点实验室, 中国
  • 收稿日期:2024-10-31 修回日期:2024-12-02 接受日期:2024-12-17
  • 通讯作者: 武建辉
  • 基金资助:
    科技创新2030-“脑科学与类脑研究”重大项目(2030-2021ZD0200700)

The Relationship Between Lifestyle Factors and Depression: a Cross-sectional Study of Community Populations 

  • Received:2024-10-31 Revised:2024-12-02 Accepted:2024-12-17
  • Supported by:
    STI2030-Major Projects(2030-2021ZD0200700)(2030-2021ZD0200700)
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摘要: 背景:抑郁症是全球范围内日益严重的公共卫生问题,目前根据《精神障碍诊断与统计手册(第五版)》使用人格障碍定式访谈诊断的生活行为因素与抑郁症之间的关系尚不明确。目的:探讨社区人群生活行为因素与抑郁症的关系。方法:于2022-2023年在唐山市开滦马家沟社区进行调查,通过问卷调查和体格检查收集相关信息。采用单因素,分层调整的Logistic回归模型分析生活行为因素与抑郁症的关系,使用XGBoost模型与SHapley加性解释对变量贡献值进行分析,通过亚组分析进一步分析生活行为因素与抑郁症的关系。结果:本研究共纳入2189人,其中患抑郁症312人(14.25%),未患抑郁症1877人(85.75%)。在调整了潜在混杂因素后,发现重度失眠(OR=10.516, 95% CI=6.385~17.320)、每个星期至少喝酒1次(OR=2.100, 95% CI=1.292~3.412)、每天使用手机时间≥12小时(OR=9.279, 95% CI=6.182~13.929)与抑郁症患病风险升高有关,养宠物(OR=0.632, 95% CI=0.475~0.842)、几乎每天锻炼身体(OR=0.257, 95% CI=0.162~0.407)与抑郁症患病风险降低有关,并在亚组分析中得出一致结论。XGBoost模型与SHapley加性解释分析得到各变量贡献值分别为失眠情况(SHAP value=0.051)、锻炼身体情况(SHAP value=0.034)、饮酒情况(SHAP value=0.024)、每天手机使用时长(SHAP value=0.018)、是否养宠物(SHAP value=0.013)。结论:失眠情况是生活行为因素中对抑郁症影响最重要的变量,其次分别是锻炼身体情况、饮酒情况、每天手机使用时长、是否养宠物。

关键词: 生活行为因素, 抑郁症, 横断面研究, 社区人群

Abstract: Background Depression is an increasingly serious public health problem worldwide, and the relationship between lifestyle factors diagnosed using personality disorder formulaic interviews according to the Diagnostic and Statistical Manual of Mental Disorders (Fifth Edition) and depression is currently unclear. Objective To explore the relationship between lifestyle behavior factors and depression in community populations. Method A survey was conducted in Majiagou Community, Kailuan, Tangshan City from 2022 to 2023, and relevant information was collected through questionnaire surveys and physical examinations. Adopting a single factor, stratified adjusted logistic regression model to analyze the relationship between lifestyle factors and depression, using the XGBoost model and SHapley additive interpretation to analyze the contribution values of variables, and further analyzing the relationship between lifestyle factors and depression through subgroup analysis. Result A total of 2189 people were included in this study, including 312 people (14.25%) with depression and 1877 people (85.75%) without depression. After adjusting for potential confounding factors, it was found that severe insomnia (OR=10.516, 95% CI=6.385~17.320), drinking alcohol at least once a week (OR=2.100, 95% CI=1.292~3.412), and using mobile phones for≥12 hours a day (OR=9.279, 95% CI=6.182~13.929) were associated with an increased risk of depression. Keeping pets (OR=0.632, 95% CI=0.475~0.842) and exercising almost every day (OR=0.257, 95% CI=0.162~0.407) were associated with a reduced risk of depression, and consistent conclusions were drawn in subgroup analysis. The XGBoost model and SHapley additive explanatory analysis obtained the contribution values of each variable as insomnia (SHAP value=0.051), physical exercise (SHAP value=0.034), alcohol consumption (SHAP value=0.024), daily mobile phone usage duration (SHAP value=0.018), and whether or not pets are kept (SHAP value=0.013). Conclusion Insomnia is the most important variable affecting depression among lifestyle factors, followed by physical exercise, alcohol consumption, daily mobile phone usage, and whether or not pets are kept.

Key words: lifestyle behavior factors, depression, cross-sectional study, community populations