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Analysis of Epidemiological Characteristics of Hypospadias in Shaanxi Area from 2000 to 2015
- XU Guo-shun, WANG An-hui, NI Jian-xin, ZHU Yue-hua, ZHENG Yu, YU Lei
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2016, 19(33):
4110-4114.
DOI: 10.3969/j.issn.1007-9572.2016.33.018
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Background Nearly 20 to 40 years,the morbidity of hypospadias worldwide increases year by year,and the epidemiological survey and research in Shaanxi area is lacking domestically.Objective To understand the epidemiological characteristics of hypospadias in Shaanxi,and to provide reference for the prevention of hypospadias in this region.Methods 429 hospitalized patients with hypospadias in Department of Urology of Xijing Hospital from September 2000 to December 2015 were retrospectively selected as research objects.The clinical data of patients were analyzed,and the admission age distribution of the patients,the year of birth-number of cases distribution,the years of hospitalization-number of cases distribution,distribution of urban and rural areas,geographical distribution,clinical classification distribution and other combination of malformations situation were described.Results The admission age of patients was（1.33-36.75）,the average admission age was（8.50±6.17）;P25=4.08,P50=6.08,P75=11.50.Among the 429 patients,the birth year was from 1971 to 2012,only 1 case was born in 1971,and the number of cases that born before 1991 every year was below 10,of which no patient was born between 1972 and 1978,and in 1981，1985;since 1992,the number of cases had a wave-like increasing,reached its peak in 2005,and then began to decline gradually;in 2000,there were 3 hospitalized cases,the number of hospitalized cases per year from 2000 to 2015 was in a wave-like rising tendency,and reached its peak in 2015,and then began to decline gradually.Of the 429 patients,145（33.8%） were in urban area and 284（66.2%） in rural area;and 289（67.4%） in Guanzhong area,including 129（44.6%） in Xi’an,73（25.3%） in Weinan,63（21.8%） in Xianyang,21（7.3%） in Baoji,and 3（1.0%） in Tongchuan;and 72（16.8%） in northern Shaanxi,including 38（52.8%） in Yulin and 34（47.2%） in Yan’an;and 68（15.8%） in southern Shaanxi,including 26（38.2%） in Hanzhong,23（33.8%） in Shaangluo and 19（28.0%） in Ankang.429 cases were treated with traditional clinical classification:367 cases（85.5%） of body of penis type,50（11.7%） of balanic type,9（2.1%） of scrotal type and 3（0.7%） of perineum type;clinical classification of DUCKETT:50（11.6%） cases of anterior segment type,of which 41（82.0%） with coronal sulcus type and 9（18.0%） with balanic type;217 cases（50.6%） of middle segment type;and 162 cases（37.8%） of posterior segment type,of which 151（93.2%） of penis-scrotum type,8（4.9%） of scrotal type and 3（1.9%） of perineal type.Of the 429 patients,379（88.3%） had simple hypospadias and 50（11.7%） had combination of other malformations;of which 40（80.0%） were combined with one kind of deformity,8（16.0%） were combined with two kinds of deformities,2（4.0%） were combined with three kinds of deformities;38（76.0%） were combined with genitourinary abnormalities 〔of which 34 cases（89.5%） with cryptorchidism deformity〕,9（18.0%） were combined with cardiovascular malformation,4（8.0%） were combined with musculoskeletal malformation and 7（14.0%） with other diseases.Conclusion The morbidity rate of hypospadias in Shaanxi area is in an increasing tendency from 2000 to 2015,the morbidity rate in rural area is higher than that in urban area,and the morbidity rate in Guanzhong area is relatively high.The most common type of hypospadias is body of penis type,small part of hypospadias patients are combined with other malformations,and the most common is the combination with genitourinary system malformations,especially cryptorchidism malformation,and congenital heart disease is the most common one in the combination with cardiovascular system malformations.
