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Sexual Dysfunction Status and Influencing Factors of Female Patients with Systemic Lupus Erythematosus
- QIN Yi, GU Zhi-feng, LI Li-ren, SANG Yan
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2016, 19(34):
4187-4195.
DOI: 10.3969/j.issn.1007-9572.2016.34.008
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Objective To investigate sexual dysfunction status of Chinese female patients with systemic lupus erythematosus（SLE） and its influencing factors.Methods Eighty female SLE patients from Affiliated Hospital of Nantong University from October 2014 and October 2015 were enrolled to conduct questionnaire investigation.The questionnaires included General Information Questionnaire,Female Sexual Function Index（FSFI） in Chinese Version,Systemic Lupus Erythematosus Disease Activity Index（SLEDAI）,and 36-item Short-Form Health Survey Questionnaire（SF-36） in Chinese version.A total of 85 questionnaires were sent out and 80 were recovered with a response rate of 94.1%.Results There were 61 patients（76.2%） with sexual dysfunction,including 58（72.5%） loss of libido and 54（67.5%） had difficulties in sexual arousal.The FSFI total scores of patients were correlated with age,years of marriage,age at menarche,menopause or not,combining with heart disease,taking nonsteroidal antiinflammatory drugs,presence of vasculitis and pyuria,dimensional scores of physical function,physical role function and emotional function in SF-36（P<0.05）;the scores of sexual desire were correlated with age,years of marriage,menopause or not,combining with heart disease,presence of vasculitis,dimensional scores of physical function and physical role function in SF-36（P<0.05）;the scores of sexual arousal were correlated with age,years of marriage,menopause or not,combining with heart disease,presence of vasculitis and pyuria,dimensional scores of physical function,physical role function and emotional function in SF-36（P<0.05）;the scores of vaginal lubrication degree were correlated with age,years of marriage,age at menarche,menopause or not,number of pregnancy,combining with heart disease,taking nonsteroidal antiinflammatory drugs,presence of vasculitis,pyuria and mucosal ulcer,dimensional scores of physical function,physical role function and emotional function in SF-36（P<0.05）;the scores of orgasm were correlated with age,years of marriage,menopause or not,combining with heart disease,taking nonsteroidal antiinflammatory drugs,presence of vasculitis and pyuria,physical function,dimensional scores of physical function,physical role function and emotional function in SF-36（P<0.05）;the scores of satisfaction degree of sexual life were correlated with age,years of marriage,menopause or not,age at menopause,combining with heart disease,presence of vasculitis and pleurisy,dimensional scores of physical function,physical role function and emotional function in SF-36（P<0.05）;the scores of dyspareunia were correlated with age,years of marriage,age at menarche,menopause or not,combining with heart disease,taking nonsteroidal antiinflammatory drugs,presence of vasculitis and pyuria,the dimensional scores of physical function,physical role function,body pain and emotional function（P<0.05）.Multiple linear regression analysis results showed that combining with heart disease was the influencing factor of scores of sexual desire,sexual arousal,vaginal lubrication and dyspareunia in FSFI among female SLE patients;presence of vasculitis was the influencing factor of total score and scores of sexual arousal,vaginal lubrication,orgasm and dyspareunia in FSFI;the dimensional score of physical role function was the influencing factor of scores of sexual arousal;mucosal ulcer was the influencing factor of scores of vaginal lubrication（P<0.05）.Conclusion The Chinese female SLE patients present a high incidence of sexual dysfunction,and its main types are loss of libido and difficulties in sexual arousal,and combining with heart disease,presence of vasculitis and mucosal ulcers,and lacking in physical role function are the influencing factors.
