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    Statin Use for the Primary Prevention of Cardiovascular Disease in Adults: Interpretation of the U.S. Preventive Services Task Force Recommendation Statement
    SHI Weili, LI Mingyan, DUAN Hongyan
    Chinese General Practice    2024, 27 (12): 1405-1412.   DOI: 10.12114/j.issn.1007-9572.2023.0849
    Abstract460)   HTML22)    PDF(pc) (1475KB)(504)       Save

    Cardiovascular disease (CVD) is the leading cause of death. It is well known that statins can reduce the risk of CVD and CVD-related death through lipid-lowering, anti-inflammatory, and plaque-stabilizing effects. In August 2022, the U.S. Preventive Services Task Force (USPSTF) conducted an updated recommendations statement on statins for primary prevention of CVD based on new evidence on the benefits and potential harms of statins in reducing CVD morbidity/mortality and all-cause mortality. The USPSTF recommends statins for the primary prevention of CVD for adults aged 40 to 75 years with 1 or more CVD risk factors and an estimated 10-year CVD risk of 10% or greater (B recommendation). The USPSTF recommends that clinicians selectively offer statins for the primary prevention of CVD in adults aged 40 to 75 years who have 1 or more of CVD risk factors and an estimated 10-year CVD risk of 7.5% to less than 10% (C recommendation). The USPSTF concludes that the current evidence is insufficient to assess the balance of benefits and harms of using statins for primary prevention of CVD events and mortality in adults aged 76 years and above (I statement). This article interprets the latest recommendations in the context of China to provide reference for the use of statins for the primary prevention of CVD in China.

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    Obstructive Sleep Apnea in Adults Screening: Interpretation of the U.S. Preventive Services Task Force Recommendation Statement
    ZENG Lingfeng, ZHANG Hui, LEI Si, ZHUO Hui, YE Yun, XU Yan, LUO Yingquan
    Chinese General Practice    2024, 27 (12): 1412-1416.   DOI: 10.12114/j.issn.1007-9572.2023.0850
    Abstract591)   HTML27)    PDF(pc) (1377KB)(383)       Save

    Obstructive sleep apnea hypopnea syndrome (OSAHS) in adults is a common sleep-breathing disorder closely associated with hypertension, diabetes, cardiovascular diseases, and other health concerns. Despite its widespread impact on global health, the screening and diagnosis of OSAHS is still not widely available in clinical practice. In this context, the U.S. Preventive Services Task Force (USPSTF) has recently released updated recommendations for adult OSAHS screening to help more people identify and treat potential sleep-breathing disorders. This article interprets the latest recommendations and consider the practical situation in China, providing reference for OSAHS screening of adults in China.

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