Chinese General Practice ›› 2026, Vol. 29 ›› Issue (27): 3969-3975.DOI: 10.12114/j.issn.1007-9572.2025.0416

• Article • Previous Articles     Next Articles

Analysis of Prevalence and Influencing Factors of Cardiovascular-kidney-metabolic Syndrome among Adults in Haidian District, Beijing

  

  1. Haidian District Center for Disease Control and Prevention, Beijing 100094, China
  • Received:2025-11-25 Revised:2026-03-30 Published:2026-09-20 Online:2026-08-11
  • Contact: CAO Wendong

北京市海淀区成人心血管-肾脏-代谢综合征的患病情况及影响因素研究

  

  1. 100094 北京市海淀区疾病预防控制中心
  • 通讯作者: 曹文栋
  • 作者简介:

    作者贡献:

    刘振宇负责文章的构思与设计、统计学处理、结果的分析与解释、论文撰写;姚清、王江敏负责数据收集、整理;刘振宇、王文东负责论文的修订;曹文栋负责文章的质量控制及审校。

  • 基金资助:
    北京高层次创新创业人才支持计划"医疗卫生"青年骨干(G202533342); 北京市卫生健康和科技成果适宜技术推广项目(BHTPP2024043); 海淀区公共卫生体系建设示范项目(HDPHS2025-10); 北京慢性病防治与健康教育研究会2025年"青苗行动"基层专项课题(MBZX202501-0080)

Abstract:

Background

With the changes in modern lifestyles and the acceleration of population aging, the incidence of obesity, cardiovascular diseases, chronic kidney disease, and metabolic syndrome has increased rapidly. However, research on cardiovascular-kidney-metabolic (CKM) syndrome remains relatively limited. There is an urgent need for regionally representative epidemiological studies to obtain evidence, providing data support and a theoretical basis for formulating strategies and measures for chronic disease prevention and control.

Objective

To investigate the prevalence and influencing factors of CKM syndrome in Haidian District, Beijing.

Methods

A total of 8 130 respondents from the 2024 Haidian District Adult Chronic Disease and Related Risk Factors Surveillance Program were included. Baseline data, physical examination results, and laboratory indicators were collected. Estimated glomerular filtration rate (eGFR), BMI, and urine albumin-to-creatinine ratio (UACR) were calculated. A multivariate Logistic regression model was constructed to explore the influencing factors of advanced CKM syndrome.

Results

In the overall population, the prevalence of CKM syndrome stages 0, 1, 2, 3, 4, and advanced CKM syndrome were 17.0% (95%CI=15.8%-18.3%), 22.2% (95%CI=20.8%-23.6%), 54.4% (95%CI=52.9%-55.9%), 2.8% (95%CI=2.3%-3.5%), 3.6% (95%CI=3.1%-4.1%), and 6.4% (95%CI=5.7%-7.2%), respectively. Multivariate Logistic regression analysis showed that in the total population, age groups 40-59 years (OR=4.52, 95%CI=2.18-9.38) and 60-79 years (OR=33.92, 95%CI=18.62-61.77), education level of junior high school (OR=2.02, 95%CI=1.20-3.42) and high school (OR=1.75, 95%CI=1.04-2.94), smoking (OR=1.82, 95%CI=1.40-2.37), and sleep duration >9 h (OR=1.36, 95%CI=1.04-1.78) were risk factors for advanced CKM syndrome (P<0.05). Being married (OR=0.59, 95%CI=0.42-0.85) and excessive red meat intake (OR=0.72, 95%CI=0.56-0.92) were protective factors (P<0.05). In the male population, age groups 40-59 years (OR=4.29, 95%CI=2.16-8.50) and 60-79 years (OR=26.75, 95%CI=14.24-50.23), education level of junior high school (OR=1.94, 95%CI=1.06-3.54), smoking (OR=1.81, 95%CI=1.35-2.43), and sleep duration<7 h (OR=1.70, 95%CI=1.08-2.69) were risk factors (P<0.05); excessive red meat intake (OR=0.70, 95%CI=0.54-0.91) was a protective factor (P<0.05). Among females, age group 60-79 years (OR=37.08, 95%CI=11.86-115.93) and sleep duration >9 h (OR=1.73, 95%CI=1.16-2.58) were risk factors (P<0.05); being married (OR=0.41, 95%CI=0.22-0.75) was a protective factor (P<0.05).

Conclusion

The prevalence of CKM syndrome is high among the adult population in Haidian District, Beijing. Future efforts should prioritize monitoring and intervention in high-risk groups, including the elderly, males, smokers, unmarried individuals, those with excessive sleep duration, and those with insufficient red meat intake, by developing and implementing more effective public health policies to reduce the disease burden of CKM syndrome.

Key words: Cardiovascular-kidney-metabolic syndrome, Risk factors, Epidemiology

摘要:

背景

随着现代生活方式的改变和人口老龄化进程的加速,肥胖、心血管疾病、慢性肾脏病和代谢综合征的发病数量迅速增加,但有关心血管-肾脏-代谢(CKM)综合征的研究较为有限,亟须通过具有地区代表性的流行病学研究获取证据,为制定慢性病防控策略和措施提供数据支持与理论依据。

目的

了解北京市海淀区CKM综合征的患病率和影响因素。

方法

纳入2024年北京市海淀区成人慢性病及其危险因素监测项目8 130名受访者为研究对象,收集受试者基线资料、体格检查结果及实验室检查指标,计算估算肾小球滤过率(eGFR)、BMI、尿白蛋白肌酐比值(UACR)。构建多因素Logistic回归模型探讨晚期CKM综合征的影响因素。

结果

在总体人群中,CKM综合征0期、1期、2期、3期、4期和晚期CKM综合征患病率分别为17.0%(95%CI=15.8%~18.3%)、22.2%(95%CI=20.8%~23.6%)、54.4%(95%CI=52.9%~55.9%)、2.8%(95%CI=2.3%~3.5%)、3.6%(95%CI=3.1%~4.1%)和6.4%(95%CI=5.7%~7.2%)。多因素Logistic回归分析结果显示,在总人群中,年龄组为40~59岁(OR=4.52,95%CI=2.18~9.38)和60~79岁(OR=33.92,95%CI=18.62~61.77)、文化程度为初中(OR=2.02,95%CI=1.20~3.42)和高中(OR=1.75,95%CI=1.04~2.94)、吸烟(OR=1.82,95%CI=1.40~2.37)、睡眠时长>9 h(OR=1.36,95%CI=1.04~1.78)为晚期CKM综合征的危险因素(P<0.05);已婚(OR=0.59,95%CI=0.42~0.85)、红肉摄入量过多(OR=0.72,95%CI=0.56~0.92)为晚期CKM综合征的保护因素(P<0.05)。男性人群中,年龄组为40~59岁(OR=4.29,95%CI=2.16~8.50)和60~79岁(OR=26.75,95%CI=14.24~50.23)、文化程度为初中(OR=1.94,95%CI=1.06~3.54)、吸烟(OR=1.81,95%CI=1.35~2.43)、睡眠时长<7 h(OR=1.70,95%CI=1.08~2.69)为晚期CKM综合征的危险因素(P<0.05);红肉摄入量过多(OR=0.70,95%CI=0.54~0.91)为晚期CKM综合征的保护因素(P<0.05)。女性人群中,年龄组为60~79岁(OR=37.08,95%CI=11.86~115.93)、睡眠时长>9 h(OR=1.73,95%CI=1.16~2.58)为晚期CKM综合征的危险因素(P<0.05);已婚(OR=0.41,95%CI=0.22~0.75)为晚期CKM综合征的保护因素(P<0.05)。

结论

北京市海淀区成年人群CKM综合征患病率较高,未来应重点关注老年人、男性、吸烟者、未婚、睡眠时间过长、红肉摄入量过少的人群,制定并推行更为有效的公共卫生政策,从而降低CKM综合征的疾病负担。

关键词: 心血管-肾脏-代谢综合征, 危险因素, 流行病学